K-Dense-AI / scientific-agent-skills
Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 190,000+ scientists worldwide. 165 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.
https://github.com/K-Dense-AI/scientific-agent-skills
Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 190,000+ scientists worldwide. 165 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.
https://github.com/K-Dense-AI/scientific-agent-skills
GitHub
GitHub - K-Dense-AI/scientific-agent-skills: Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used…
Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 190,000+ scientists worldwide. 165 ready-to-use validated skills plus 100+ scientific databases covering bio...
Citry
Fully typed frontend framework for Python with server events and Alpine.js, inspired by Vue and Livewire.
https://github.com/citry-dev/citry
Fully typed frontend framework for Python with server events and Alpine.js, inspired by Vue and Livewire.
https://github.com/citry-dev/citry
GitHub
GitHub - citry-dev/citry: Fully typed frontend framework for Python with server events and Alpine.js, inspired by Vue and Livewire.
Fully typed frontend framework for Python with server events and Alpine.js, inspired by Vue and Livewire. - citry-dev/citry
Ruff, mypy, pytest, and then what?
Structural quality in the age of AI-written Python. What the standard toolchain checks, what it does not, and what a real agent-written repository looks like when you measure it.
https://codescan.dev/blog/ruff-mypy-pytest-and-then-what
Structural quality in the age of AI-written Python. What the standard toolchain checks, what it does not, and what a real agent-written repository looks like when you measure it.
https://codescan.dev/blog/ruff-mypy-pytest-and-then-what
codescan.dev
Ruff, mypy, pytest, and then what?
Structural quality in the age of AI-written Python. What the standard toolchain checks, what it does not, and what a real agent-written repository looks like when you measure it.
TPU Inference Externalization Full Steam Ahead
The article examines Google’s push to make TPUs a first-class platform for external LLM inference, including TorchTPU, vLLM, SGLang, and a rapidly maturing open software stack. Benchmarks TPUv7 Ironwood against NVIDIA B200/B300 and dives into the kernel, memory, networking, and serving optimizations behind its performance-per-dollar gains.
https://inferencex.semianalysis.com/blog/tpu-inferencex-full-steam
The article examines Google’s push to make TPUs a first-class platform for external LLM inference, including TorchTPU, vLLM, SGLang, and a rapidly maturing open software stack. Benchmarks TPUv7 Ironwood against NVIDIA B200/B300 and dives into the kernel, memory, networking, and serving optimizations behind its performance-per-dollar gains.
https://inferencex.semianalysis.com/blog/tpu-inferencex-full-steam
Semianalysis
TPU Inference Externalization Full Steam Ahead
First third-party TPUv7 Ironwood inference results on the InferenceX Official Preview. Apples-to-apples FP8 comparisons against B200 and B300, the native TorchTPU PyTorch stack replacing TorchAX, the Pallas kernel and MXU optimizations behind the numbers…
cloud-in-a-bottle
Deploy, use, and share web apps on a server you control. Your apps, data, and infrastructure stay yours.
https://github.com/cloud-in-a-bottle/cloud-in-a-bottle
Deploy, use, and share web apps on a server you control. Your apps, data, and infrastructure stay yours.
https://github.com/cloud-in-a-bottle/cloud-in-a-bottle
GitHub
GitHub - cloud-in-a-bottle/cloud-in-a-bottle: Deploy, use, and share web apps on a server you control. Your apps, data, and infrastructure…
Deploy, use, and share web apps on a server you control. Your apps, data, and infrastructure stay yours. - cloud-in-a-bottle/cloud-in-a-bottle
Reading __dict__ once permanently deoptimizes attribute access
Since 3.11 attribute access has not been a dict lookup, and reading dict once takes the specialized path away for good
https://deadlovelll.github.io/2026-09-05-reading-dict-deoptimizes-attribute-access/
Since 3.11 attribute access has not been a dict lookup, and reading dict once takes the specialized path away for good
https://deadlovelll.github.io/2026-09-05-reading-dict-deoptimizes-attribute-access/
Timofei Ivankov
Reading __dict__ once permanently deoptimizes attribute access | Timofei Ivankov
Since 3.11 attribute access has not been a dict lookup, and reading __dict__ once takes the specialized path away for good
hip-agent
A minimal coding agent harness that fits in the prompt.
https://github.com/changjonathanc/hip-agent
A minimal coding agent harness that fits in the prompt.
https://github.com/changjonathanc/hip-agent
GitHub
GitHub - changjonathanc/hip-agent: A minimal coding agent harness that fits in the prompt
A minimal coding agent harness that fits in the prompt - changjonathanc/hip-agent
Teaching NumPy's ufuncs new tricks
The post explains how NumPy’s universal functions (ufuncs) work in C and how their internals were upgraded to support multi-output reductions, enabling the long-requested np.minmax function. It also covers ongoing work on segmented reductions for ragged data and converting existing functions into generalized ufuncs (gufuncs) for subarray processing.
https://labs.quansight.org/blog/teaching-numpys-ufuncs-new-tricks
The post explains how NumPy’s universal functions (ufuncs) work in C and how their internals were upgraded to support multi-output reductions, enabling the long-requested np.minmax function. It also covers ongoing work on segmented reductions for ragged data and converting existing functions into generalized ufuncs (gufuncs) for subarray processing.
https://labs.quansight.org/blog/teaching-numpys-ufuncs-new-tricks
AWS Lambda Functions in Python: A Practical Guide
https://middleware.io/blog/aws-lambda-functions-in-python/
https://middleware.io/blog/aws-lambda-functions-in-python/
Middleware
AWS Lambda Functions in Python: A Practical Guide
Learn how to build, deploy, and monitor AWS Lambda functions in Python, from handlers and triggers to memory tuning, cold starts, and OpenTelemetry setup.
On solving the Jane Street Reverse Engineering Challenge
Jane Street’s ASIC reverse-engineering challenge turns a raw chip-layout file into a month-long puzzle about reconstructing how the circuit works. The author uses Python, graph algorithms, Verilog, simulation, and Z3 to recover the design, solve the challenge, and even uncover a real hardware bug.
https://jestoph.com/2026/09/04/jane-street-challenge.html
Jane Street’s ASIC reverse-engineering challenge turns a raw chip-layout file into a month-long puzzle about reconstructing how the circuit works. The author uses Python, graph algorithms, Verilog, simulation, and Z3 to recover the design, solve the challenge, and even uncover a real hardware bug.
https://jestoph.com/2026/09/04/jane-street-challenge.html
jestoph’s tech blog
On solving the Jane Street Reverse Engineering Challenge
Or: Why do I always do things the hard way?
package-doctor: finds Python dependencies at a trust boundary with no one left to fix them
Flags packages that handle untrusted input and look unmaintained. Ranks advisories by real exploitation. Runs beside pip-audit.
https://github.com/binuka200/package-doctor
Flags packages that handle untrusted input and look unmaintained. Ranks advisories by real exploitation. Runs beside pip-audit.
https://github.com/binuka200/package-doctor
GitHub
GitHub - binuka200/package-doctor: Scan Python dependencies for exploited CVEs and abandoned packages that handle untrusted input…
Scan Python dependencies for exploited CVEs and abandoned packages that handle untrusted input, ranked by CISA KEV and EPSS. Runs in CI and as a Claude Code hook. - binuka200/package-doctor
Inside the megakernel serving engine for North Mini Code
A technical deep dive into how Cohere’s approach to megakernels delivers 1.58x faster LLM serving on H100 devices.
https://cohere.com/blog/megakernels
A technical deep dive into how Cohere’s approach to megakernels delivers 1.58x faster LLM serving on H100 devices.
https://cohere.com/blog/megakernels
Cohere
Cohere's North Mini Code Megakernel Serving Engine | Cohere
Cohere presents the first production-ready LLM serving system built around a decode megakernel, achieving 1.58× speedup over vLLM.
How to Stop Third-Party APIs From Ruining Your Code
The video explains the Facade pattern using a Stripe payment integration to show how it can isolate external APIs from application code. It covers reducing coupling, improving testability, and creating cleaner boundaries that are easier to maintain and evolve.
https://www.youtube.com/watch?v=vskwNNdnqMc
The video explains the Facade pattern using a Stripe payment integration to show how it can isolate external APIs from application code. It covers reducing coupling, improving testability, and creating cleaner boundaries that are easier to maintain and evolve.
https://www.youtube.com/watch?v=vskwNNdnqMc
YouTube
How to Stop Third-Party APIs From Ruining Your Code
🧱 Build software that lasts. Join the Software Design Mastery program → https://arjan.codes/mastery.
In this video, I use a Stripe payment integration to show what a Facade should really do. You'll learn how to reduce coupling, keep external APIs from leaking…
In this video, I use a Stripe payment integration to show what a Facade should really do. You'll learn how to reduce coupling, keep external APIs from leaking…
Libraries Run Rust Inside Python (With PyO3)
https://belderbos.dev/blog/how-libraries-run-rust-inside-python/
https://belderbos.dev/blog/how-libraries-run-rust-inside-python/
belderbos.dev
How Libraries Run Rust Inside Python (with PyO3)
Build a Rust JSON parser into a module Python can import with PyO3, then see what the return trip costs when Rust data becomes Python dicts and lists.
Turn SQLite Into A Vector Database For RAG
This video demonstrates how to turn SQLite into a vector database for AI applications using the sqlite-vec and sqlite-ai-vector extensions. It covers setting up both packages in Python with OpenAI embeddings, implementing similarity search and metadata filtering, and benchmarking their performance, memory efficiency, and quantization capabilities.
https://www.youtube.com/watch?v=VlEoSzkd2gQ
This video demonstrates how to turn SQLite into a vector database for AI applications using the sqlite-vec and sqlite-ai-vector extensions. It covers setting up both packages in Python with OpenAI embeddings, implementing similarity search and metadata filtering, and benchmarking their performance, memory efficiency, and quantization capabilities.
https://www.youtube.com/watch?v=VlEoSzkd2gQ
YouTube
Turn SQLite Into A Vector Database For RAG
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🐍 The Python Bible Book: https://www.neuralnine.com/books/
💻 The Algorithm Bible Book: https://www.neuralnine.com/books/
microsoft / data-formulator
🪄 Data Formulator is an interactive AI-powered data analysis system makes it easy to connect, explore and visualize data.
https://github.com/microsoft/data-formulator
🪄 Data Formulator is an interactive AI-powered data analysis system makes it easy to connect, explore and visualize data.
https://github.com/microsoft/data-formulator
GitHub
GitHub - microsoft/data-formulator: 🪄 Data Formulator is an interactive AI-powered data analysis system makes it easy to connect…
🪄 Data Formulator is an interactive AI-powered data analysis system makes it easy to connect, explore and visualize data. - microsoft/data-formulator
Qwen-Drive
An Initial Step towards a Vision-Language Foundation Model for Autonomous Driving.
https://github.com/QwenLM/Qwen-Drive-1.0
An Initial Step towards a Vision-Language Foundation Model for Autonomous Driving.
https://github.com/QwenLM/Qwen-Drive-1.0
GitHub
GitHub - QwenLM/Qwen-Drive-1.0: An Initial Step towards a Vision-Language Foundation Model for Autonomous Driving
An Initial Step towards a Vision-Language Foundation Model for Autonomous Driving - QwenLM/Qwen-Drive-1.0
Python sets and dictionaries can have quadratic-time performance
https://lemire.me/blog/2026/09/03/python-sets-and-dictionaries-can-have-quadratic-time-performance/
https://lemire.me/blog/2026/09/03/python-sets-and-dictionaries-can-have-quadratic-time-performance/
Daniel Lemire's blog
Python sets and dictionaries can have quadratic-time performance
In Python, the dict data structure is the conventional key-value structure. E.g., you might store a list of names as keys and have their phone numbers as values. Valentin Ignatev wrote this amusing post on X: It is indeed widely believed that, in the strict…