Pediatrics Questions Channel πŸ’‰πŸ’Š
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🩺 Daily Pediatrics Q&A | Clinical Scenarios | Evidence-based Notes | For Med Students & Practitioners.

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A 5-year-old presents with painless cervical lymphadenitis. There is no systemic illness. Culture shows a slow-growing nontuberculous mycobacterium commonly found in water sources. What is the most likely causative agent?
Anonymous Quiz
10%
Mycobacterium tuberculosis
11%
Mycobacterium leprae
46%
Mycobacterium avium-intracellulare
33%
Mycobacterium scrofulaceum
A newborn presents with hearing loss. Imaging shows periventricular intracranial calcifications. Maternal history reveals a viral infection during pregnancy. Which is the most likely causative agent?
Anonymous Quiz
16%
Toxoplasma gondii
21%
Rubella virus
57%
Cytomegalovirus
4%
Herpes simplex virus
2%
Varicella-zoster virus
πŸ‘1
πŸ–Š Positive feedback loops act to increase the stimulus that triggered them.

"A Spark causes fire which releases more heat & causes more fire. You hit someone which makes them mad & makes them hit you which makes you mad & hit them back."
πŸ‘2
The Landau reflex appears at approximately:
Anonymous Quiz
21%
Birth
26%
1 month
30%
6 months
22%
3 months
A patient with SLE develops worsening nephritis. Rising titers of which antibody would most strongly correlate with disease activity?
Anonymous Quiz
15%
Anti-Smith
16%
Anti-Ro (SSA)
5%
Anti-histone
10%
Anti-phospholipid
54%
Anti-dsDNA
A 23-year-old woman presents with fatigue, joint pain, and a malar rash. Labs show anti-dsDNA antibodies and low C3/C4 levels. Urinalysis reveals proteinuria and RBC casts. Which mechanism most directly explains her renal findings?
Anonymous Quiz
8%
Direct cytotoxic T-cell–mediated podocyte injury
54%
Deposition of circulating immune complexes in glomeruli
3%
IgA deposition in mesangium
15%
Anti-GBM antibody binding to basement membrane
20%
ANCA-mediated neutrophil activation
A 22-year-old patient presents with malar rash and arthritis. Which population has the highest overall incidence of SLE?
Anonymous Quiz
7%
Prepubertal children
5%
Men over age 60
11%
Postmenopausal women
77%
Women of reproductive age
1%
Elderly men
Which genetic marker is most strongly associated with spondyloarthropathies?
Anonymous Quiz
12%
HLA-DR4
56%
HLA-B27
13%
HLA-DQ2
19%
HLA-DR3
1%
HLA-B51
A patient with psoriasis develops dactylitis and nail pitting. Which condition is most likely?
Anonymous Quiz
4%
Rheumatoid arthritis
9%
Gouty arthritis
82%
Psoriatic arthritis
4%
SLE
1%
Osteoarthritis
A 25-year-old woman presents with an erythematous rash across her cheeks and nasal bridge that worsens after sun exposure. The rash spares the nasolabial folds. What is the most likely diagnosis?
Anonymous Quiz
10%
Rosacea
10%
Seborrheic dermatitis
73%
Malar rash of SLE
3%
Dermatomyositis
3%
Contact dermatitis
A patient with chronic scaly plaques on the scalp and face develops areas of scarring alopecia. Biopsy shows interface dermatitis. Which form of lupus is most likely?
Anonymous Quiz
5%
Neonatal lupus
13%
Acute cutaneous lupus
9%
Drug-induced lupus
59%
Discoid lupus erythematosus
15%
Subacute cutaneous lupus
πŸ–Š Negative feedback loop: act to decrease the stimulus that triggered them.