A 28-year-old woman presents with easy bruising and mucosal bleeding. Labs show isolated thrombocytopenia with normal PT and PTT. Bone marrow biopsy reveals increased megakaryocytes. What is the most likely diagnosis?

During acute inflammation, inflammatory cells and plasma proteins migrate from the bloodstream to the primary site of injury. Into which compartment do they move?

A biopsy specimen from an acutely inflamed tissue most characteristically demonstrates which of the following findings?

Following acute tissue injury, the healing process begins during the inflammatory phase. Which of the following correctly distinguishes regeneration from repair?

Which of the following statements about dermatomyositis is correct?

What is the correct immediate postnatal management for a newborn with congenital diaphragmatic hernia?

Which of the following statements is correct regarding phimosis and paraphimosis?

A patient presents with a human bite that breaks the skin. What is the typical empiric treatment?

In a congenital or simple hydrocele, why is aspiration of fluid generally not recommended?

A newborn presents with severe hypospadias, and one testis is undescended. What is the first step in evaluation?

A 4-year-old child presents with severe intellectual disability, minimal speech, frequent inappropriate laughter, seizures, and an ataxic gait. Genetic testing shows loss of maternal gene expression at chromosome 15q11–q13. The most likely diagnosis is?

A 2-month-old infant has a soft, nontender bulge at the umbilicus that protrudes when crying and is easily reducible. The infant is otherwise healthy. What is the most appropriate management?

Teenager with progressive ataxia, absent reflexes, loss of vibration sense, and hypertrophic cardiomyopathy. GAA repeat expansion on chromosome 9. The Cause is?

A newborn has severe hypotonia and poor feeding. At age 5, he develops hyperphagia and obesity. Genetic testing reveals a deletion on chromosome 15q11–q13 inherited from his father. What is the most likely diagnosis?

A 2-year-old boy presents with abdominal distension and a palpable right upper quadrant mass. Laboratory studies show markedly elevated alpha-fetoprotein (AFP). Imaging reveals a solitary liver mass. What is the most likely diagnosis?

A 2-year-old child presents with intermittent jaundice and abdominal pain. RUQ ultrasound shows dilation of the gallbladder and a fusiform dilation of the extrahepatic biliary tree that communicates with the bile ducts. What is the most likely diagnosis?

A premature neonate with jaundice is started on intravenous antibiotics for suspected sepsis. Shortly after receiving therapy, the infant develops worsening hyperbilirubinemia. Which of the following drugs is most likely responsible?

A full-term infant is exclusively breastfed. At what age should iron supplementation typically begin to prevent iron deficiency anemia?

HbAS on electrophoresis indicates:

A 2-year-old child who is not toilet trained needs a urine culture. What is the preferred method to collect a sterile urine sample?