A 3-year-old child with sickle cell disease presents with sudden pallor, abdominal fullness, and splenomegaly. Labs show normocytic anemia with markedly elevated reticulocyte count. What distinguishes this from an aplastic crisis?
Anonymous Quiz
60%
Presence of high reticulocyte count
17%
Low reticulocyte count
10%
Macrocytic anemia
7%
Absence of splenomegaly
6%
Elevated platelet count
❤1
A 2-year-old child presents with ptosis, miosis, and anhidrosis on the right side. Imaging reveals a cervical paravertebral mass. What is the most likely diagnosis?
Anonymous Quiz
56%
Neuroblastoma
7%
Wilms tumor
18%
Retinoblastoma
13%
Rhabdomyosarcoma
6%
Pheochromocytoma
❤1
A 5-year-old child presents with jaundice, anemia, and splenomegaly. Peripheral smear shows spherocytes. Which of the following best explains the pathophysiology?
Anonymous Quiz
7%
Defective hemoglobin synthesis causing microcytosis
11%
Iron deficiency leading to decreased RBC production
10%
Enzyme deficiency causing hemolysis
58%
Defect in RBC membrane proteins (spectrin/ankyrin) leading to decreased surface area
15%
Autoimmune destruction of RBCs
A joint is examined and found to have a distinct joint cavity filled with synovial fluid, allowing free movement between articulating bones. Which type of joint is this?
Anonymous Quiz
1%
Fibrous joint
16%
Cartilaginous joint
8%
Syndesmosis
7%
Synchondrosis
68%
Synovial joint
👍2
A newborn has cyanosis that worsens with feeding and improves with crying, but cardiac and respiratory exams are normal. Attempting to pass a catheter through the nose into the oropharynx is unsuccessful. What is the most likely diagnosis?
Anonymous Quiz
5%
Tetralogy of Fallot
10%
Laryngomalacia
17%
Tracheoesophageal fistula
64%
Choanal atresia
4%
Persistent pulmonary hypertension of the newborn
👏2
A patient with acute respiratory distress is on mechanical ventilation. Positive end-expiratory pressure (PEEP) is being considered. Which of the following statements is most accurate?
Anonymous Quiz
13%
PEEP prevents alveolar collapse and is safe in pneumothorax
68%
PEEP prevents alveolar collapse but should be avoided in pneumothorax
15%
PEEP decreases alveolar distension and improves oxygenation in pneumothorax
3%
PEEP is only used in patients with normal lungs
1%
PEEP has no effect on oxygenation or alveolar stability
A 14-year-old presents with localized bone pain and swelling. Imaging shows a diaphyseal lesion in the femur with a “onion-skin” periosteal reaction. Which of the following is the most likely diagnosis?
Anonymous Quiz
1%
Giant cell tumor
22%
Osteosarcoma
71%
Ewing sarcoma
5%
Osteochondroma
1%
Chondrosarcoma
👍3
Forwarded from Black Lion | School of Medicine 💉💊
A 16-year-old male presents with nighttime leg pain that dramatically improves with aspirin. Imaging reveals a small, radiolucent nidus in the cortex of the femur. What is the most likely diagnosis?
Anonymous Quiz
18%
Osteosarcoma
38%
Osteoid osteoma
17%
Osteoblastoma
16%
Ewing sarcoma
11%
Chondroblastoma
Forwarded from Black Lion | School of Medicine 💉💊
Black Lion | School of Medicine 💉💊
A 16-year-old male presents with nighttime leg pain that dramatically improves with aspirin. Imaging reveals a small, radiolucent nidus in the cortex of the femur. What is the most likely diagnosis?
Small, round lucency
👍3
Forwarded from Black Lion | School of Medicine 💉💊
A patient presents with urethritis, and a laboratory aims to visualize Chlamydia trachomatis under the microscope. Which stain is most appropriate?
Anonymous Quiz
21%
Gram stain
27%
Ziehl-Neelsen stain
33%
Giemsa stain
9%
India ink
10%
Silver stain
👍1
An elderly patient presents with progressive gait instability, urinary incontinence & cognitive decline. MRI shows ventriculomegaly out of proportion to cortical atrophy. Which of the following best confirms the diagnosis & predicts response to treatment?
Anonymous Quiz
14%
Elevated opening pressure on lumbar puncture
42%
High-volume lumbar puncture with transient gait improvement
22%
EEG showing diffuse slowing
13%
Serum vitamin B12 level
9%
Brain biopsy
❤3
A premature neonate has a continuous machine-like murmur and bounding pulses. Echocardiography confirms a patent ductus arteriosus (PDA). Which medication promotes closure of this lesion?
Anonymous Quiz
74%
Indomethacin
10%
Milrinone
6%
Propranolol
3%
Furosemide
8%
Alprostadil