A 3-month-old infant with Down syndrome presents with poor feeding, tachypnea, and failure to thrive. Cardiac exam reveals a systolic ejection murmur at the left upper sternal border and a fixed split S2. What is the most likely diagnosis?
Anonymous Quiz
26%
Isolated atrial septal defect
10%
Tetralogy of Fallot
25%
Ventricular septal defect
10%
Patent ductus arteriosus
29%
Complete atrioventricular septal defect
newborn presents with jaundice, an enlarged tongue, and lethargy. Labs show high TSH and low free T4. What is the most likely diagnosis?
Anonymous Quiz
4%
Congenital adrenal hyperplasia
86%
Congenital hypothyroidism
5%
Neonatal sepsis
3%
Galactosemia
2%
Hypopituitarism
A newborn of a mother with poorly controlled diabetes develops tremors and jitteriness shortly after birth. What is the most common complication in infants of diabetic mothers?
Anonymous Quiz
3%
Polycythemia
9%
Hyperbilirubinemia
14%
Respiratory distress syndrome
68%
Neonatal hypoglycemia
5%
Congenital heart defects
👍2
A newborn presents with prolonged PT and aPTT. Vitamin K deficiency is suspected. Which coagulation factors are most affected?
Anonymous Quiz
6%
I, V, VIII, XIII
63%
II, VII, IX, X
18%
II, V, VII, VIII
7%
I, II, VII, X
7%
V, VII, IX, XI
❤3
A 3-year-old child with sickle cell disease presents with sudden pallor, abdominal fullness, and splenomegaly. Labs show normocytic anemia with markedly elevated reticulocyte count. What distinguishes this from an aplastic crisis?
Anonymous Quiz
60%
Presence of high reticulocyte count
17%
Low reticulocyte count
10%
Macrocytic anemia
7%
Absence of splenomegaly
6%
Elevated platelet count
❤1
A 2-year-old child presents with ptosis, miosis, and anhidrosis on the right side. Imaging reveals a cervical paravertebral mass. What is the most likely diagnosis?
Anonymous Quiz
56%
Neuroblastoma
7%
Wilms tumor
18%
Retinoblastoma
13%
Rhabdomyosarcoma
6%
Pheochromocytoma
❤1
A 5-year-old child presents with jaundice, anemia, and splenomegaly. Peripheral smear shows spherocytes. Which of the following best explains the pathophysiology?
Anonymous Quiz
7%
Defective hemoglobin synthesis causing microcytosis
11%
Iron deficiency leading to decreased RBC production
10%
Enzyme deficiency causing hemolysis
58%
Defect in RBC membrane proteins (spectrin/ankyrin) leading to decreased surface area
15%
Autoimmune destruction of RBCs
A joint is examined and found to have a distinct joint cavity filled with synovial fluid, allowing free movement between articulating bones. Which type of joint is this?
Anonymous Quiz
1%
Fibrous joint
16%
Cartilaginous joint
8%
Syndesmosis
7%
Synchondrosis
68%
Synovial joint
👍2
A newborn has cyanosis that worsens with feeding and improves with crying, but cardiac and respiratory exams are normal. Attempting to pass a catheter through the nose into the oropharynx is unsuccessful. What is the most likely diagnosis?
Anonymous Quiz
5%
Tetralogy of Fallot
10%
Laryngomalacia
17%
Tracheoesophageal fistula
64%
Choanal atresia
4%
Persistent pulmonary hypertension of the newborn
👏2
A patient with acute respiratory distress is on mechanical ventilation. Positive end-expiratory pressure (PEEP) is being considered. Which of the following statements is most accurate?
Anonymous Quiz
13%
PEEP prevents alveolar collapse and is safe in pneumothorax
68%
PEEP prevents alveolar collapse but should be avoided in pneumothorax
15%
PEEP decreases alveolar distension and improves oxygenation in pneumothorax
3%
PEEP is only used in patients with normal lungs
1%
PEEP has no effect on oxygenation or alveolar stability
A 14-year-old presents with localized bone pain and swelling. Imaging shows a diaphyseal lesion in the femur with a “onion-skin” periosteal reaction. Which of the following is the most likely diagnosis?
Anonymous Quiz
1%
Giant cell tumor
22%
Osteosarcoma
71%
Ewing sarcoma
5%
Osteochondroma
1%
Chondrosarcoma
👍3
Forwarded from Black Lion | School of Medicine 💉💊
A 16-year-old male presents with nighttime leg pain that dramatically improves with aspirin. Imaging reveals a small, radiolucent nidus in the cortex of the femur. What is the most likely diagnosis?
Anonymous Quiz
18%
Osteosarcoma
38%
Osteoid osteoma
17%
Osteoblastoma
16%
Ewing sarcoma
11%
Chondroblastoma
Forwarded from Black Lion | School of Medicine 💉💊
Black Lion | School of Medicine 💉💊
A 16-year-old male presents with nighttime leg pain that dramatically improves with aspirin. Imaging reveals a small, radiolucent nidus in the cortex of the femur. What is the most likely diagnosis?
Small, round lucency
👍3