#NAIRG_Membership
The NAIRG is a research group that fosters the development of young and keen researchers who are interested in the nervous system and its related fields. The NAIRG provides an environment where all the members are supported and challenged by mentors who are involved in every stage of every project. The NAIRG assigns each new member an important but manageable project that suits their level of expertise. The NAIRG values mentorship, responsibility, discipline, and punctuality and strives to create a culture of learning and teaching. Members are expected to become future mentors and pass the torch to the next generation of students. This approach has enabled the NAIRG to work on many projects and publish some of them in reputable journals within a span of just over a year. The NAIRG has also become an attractive place for many students in UMSHA who want to join the group and pursue their research interests. The NAIRG owes its success to hardworking mentors, members, and ever-caring supervisors. As a community, we look forward to continually improving and delivering a better understanding of neuroscience and artificial intelligence fields in medicine to help improve people's health everywhere.
@NAIRG_Channel
The NAIRG is a research group that fosters the development of young and keen researchers who are interested in the nervous system and its related fields. The NAIRG provides an environment where all the members are supported and challenged by mentors who are involved in every stage of every project. The NAIRG assigns each new member an important but manageable project that suits their level of expertise. The NAIRG values mentorship, responsibility, discipline, and punctuality and strives to create a culture of learning and teaching. Members are expected to become future mentors and pass the torch to the next generation of students. This approach has enabled the NAIRG to work on many projects and publish some of them in reputable journals within a span of just over a year. The NAIRG has also become an attractive place for many students in UMSHA who want to join the group and pursue their research interests. The NAIRG owes its success to hardworking mentors, members, and ever-caring supervisors. As a community, we look forward to continually improving and delivering a better understanding of neuroscience and artificial intelligence fields in medicine to help improve people's health everywhere.
@NAIRG_Channel
#NAIRG_Publication🧠
This study investigated the restorative and antimicrobial effects of Scrophularia striata hydroalcoholic extract (SHE) on first- and second-grade pressure ulcers in patients with brain and spinal cord lesions
📖 PDF file of this article is available in NAIRG channel
📋 Title: The antimicrobial and healing effect of Scrophularia striata Boiss hydroalcoholic extract on first-and second-grade pressure wounds in patients with brain and spinal cord injury: a randomized clinical trial. Evidence-Based Complementary and Alternative Medicine.
📥 Link: https://www.hindawi.com/journals/ecam/2022/8522937/
📎 doi: 10.1155/2022/8522937
📎 Journal name: Evidence-based Complementary and Alternative Medicine
📎 Authors: Zahra Bagheri, Amir Larki-Harchegani, Shabnam Pourmoslemi, Amir Nili-Ahmadabadi, Ebrahim Bakhtiari, Hamid Safarpour, Ali Fathi Jouzdani, Morteza Shamsizadeh
📎 Abstract: The study investigated the restorative and antimicrobial effects of Scrophularia striata hydroalcoholic extract (SHE) on first- and second-grade pressure ulcers in patients with brain and spinal cord lesions
📎 Result:This study analyzed 140 patients, dividing them into four groups based on demographic characteristics. The patients were not significantly different in terms of gender, age, occupation, education, marriage, and residence. The study found that most patients were hospitalized due to spinal cord injury (SCI) and cerebrovascular accident (CVA), with most having grade 2 ulcers. The mean ulcer size before and ten days after intervention showed a significant difference between the four groups. The decreasing process slope of the mean ulcer size in patients of experiment group 2 was steeper compared to the control and placebo groups. By the tenth day of intervention, 63.3% of patients in experiment group 1, 100% in experimental group 2, and 26.7% in the control group had healing ulcers. No complete recovery was observed in any placebo patients during ten days of intervention. The time of complete ulcer healing patients in experiment group 2 was less than in group 1 and the control group.
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This study investigated the restorative and antimicrobial effects of Scrophularia striata hydroalcoholic extract (SHE) on first- and second-grade pressure ulcers in patients with brain and spinal cord lesions
📖 PDF file of this article is available in NAIRG channel
📋 Title: The antimicrobial and healing effect of Scrophularia striata Boiss hydroalcoholic extract on first-and second-grade pressure wounds in patients with brain and spinal cord injury: a randomized clinical trial. Evidence-Based Complementary and Alternative Medicine.
📥 Link: https://www.hindawi.com/journals/ecam/2022/8522937/
📎 doi: 10.1155/2022/8522937
📎 Journal name: Evidence-based Complementary and Alternative Medicine
📎 Authors: Zahra Bagheri, Amir Larki-Harchegani, Shabnam Pourmoslemi, Amir Nili-Ahmadabadi, Ebrahim Bakhtiari, Hamid Safarpour, Ali Fathi Jouzdani, Morteza Shamsizadeh
📎 Abstract: The study investigated the restorative and antimicrobial effects of Scrophularia striata hydroalcoholic extract (SHE) on first- and second-grade pressure ulcers in patients with brain and spinal cord lesions
📎 Result:This study analyzed 140 patients, dividing them into four groups based on demographic characteristics. The patients were not significantly different in terms of gender, age, occupation, education, marriage, and residence. The study found that most patients were hospitalized due to spinal cord injury (SCI) and cerebrovascular accident (CVA), with most having grade 2 ulcers. The mean ulcer size before and ten days after intervention showed a significant difference between the four groups. The decreasing process slope of the mean ulcer size in patients of experiment group 2 was steeper compared to the control and placebo groups. By the tenth day of intervention, 63.3% of patients in experiment group 1, 100% in experimental group 2, and 26.7% in the control group had healing ulcers. No complete recovery was observed in any placebo patients during ten days of intervention. The time of complete ulcer healing patients in experiment group 2 was less than in group 1 and the control group.
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Wiley Online Library
The Antimicrobial and Healing Effect of Scrophularia striata Boiss Hydroalcoholic Extract on First‐ and Second‐Grade Pressure Wounds…
Introduction and Objectives. Pressure wound is one of the most common problems in patients with brain and spinal cord lesions leading to complications such as severe pain, infection, and frequent hos...
📋 Title: The antimicrobial and healing effect of Scrophularia striata Boiss hydroalcoholic extract on first-and second-grade pressure wounds in patients with brain and spinal cord injury: a randomized clinical trial. Evidence-Based Complementary and Alternative Medicine.
📥 Link: https://www.hindawi.com/journals/ecam/2022/8522937/
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📥 Link: https://www.hindawi.com/journals/ecam/2022/8522937/
@NAIRG_Channel
8522937.pdf
790.2 KB
📋 Title: The antimicrobial and healing effect of Scrophularia striata Boiss hydroalcoholic extract on first-and second-grade pressure wounds in patients with brain and spinal cord injury: a randomized clinical trial. Evidence-Based Complementary and Alternative Medicine.
📥 Link: https://www.hindawi.com/journals/ecam/2022/8522937/
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📥 Link: https://www.hindawi.com/journals/ecam/2022/8522937/
@NAIRG_Channel
#NAIRG_Publication🧠
Aluminum phosphide (ALP) is among the most significant causes of brain toxicity and death in many countries. Curcumin (CUR), a major turmeric component, is a potent protective agent against many diseases, including brain toxicity. This study aimed to examine the probable protection potential of nanomicelle curcumin (nanomicelle-CUR) and its underlying mechanism in a rat model of ALP-induced brain toxicity.
📖 PDF file of this article is available in NAIRG channel
📋 Title: How can nanomicelle-curcumin modulate aluminum phosphide-induced neurotoxicity?: Role of SIRT1/FOXO3 signaling pathway
📥 Link: https://www.aimspress.com/article/doi/10.3934/Neuroscience.2023005
📎 doi: 10.3934/Neuroscience.2023005
📎 Journal name: AIMS Neuroscience
2023, Volume 10, Issue 1: 56-74.
📎 Authors:
Milad Khodavysi
Nejat Kheiripour
Hassan Ghasemi
Sara Soleimani-Asl
Ali Fathi Jouzdani
Mohammadmahdi Sabahi
Zahra Ganji
Zahra Azizi
Akram Ranjbar
📎 Result: The study compared the MDA, TTG, TAC, and SOD levels of the ALP and CUR groups in brain tissue. MDA levels were significantly increased in the ALP group compared to the control group, while TTG levels were decreased in the ALP group. The ALP + CUR and ALP + nanomicelle-CUR groups had no significant difference in MDA levels compared to the control group. TAC levels were also significantly decreased in the ALP group compared to the control group, while the tissue TAC levels increased in the ALP + CUR and ALP + nanomicelle-CUR groups. The brain SOD level was significantly decreased in the ALP group compared to the control group, and the levels in the ALP + CUR and ALP + nanomicelle-CUR groups were not significantly different. The CUR and nanomicelle-CUR groups had no significant difference compared to the control group. The results suggest that the ALP group may have a higher SOD level than the CUR and nanomicelle-CUR groups.
@NAIRG_Channel
Aluminum phosphide (ALP) is among the most significant causes of brain toxicity and death in many countries. Curcumin (CUR), a major turmeric component, is a potent protective agent against many diseases, including brain toxicity. This study aimed to examine the probable protection potential of nanomicelle curcumin (nanomicelle-CUR) and its underlying mechanism in a rat model of ALP-induced brain toxicity.
📖 PDF file of this article is available in NAIRG channel
📋 Title: How can nanomicelle-curcumin modulate aluminum phosphide-induced neurotoxicity?: Role of SIRT1/FOXO3 signaling pathway
📥 Link: https://www.aimspress.com/article/doi/10.3934/Neuroscience.2023005
📎 doi: 10.3934/Neuroscience.2023005
📎 Journal name: AIMS Neuroscience
2023, Volume 10, Issue 1: 56-74.
📎 Authors:
Milad Khodavysi
Nejat Kheiripour
Hassan Ghasemi
Sara Soleimani-Asl
Ali Fathi Jouzdani
Mohammadmahdi Sabahi
Zahra Ganji
Zahra Azizi
Akram Ranjbar
📎 Result: The study compared the MDA, TTG, TAC, and SOD levels of the ALP and CUR groups in brain tissue. MDA levels were significantly increased in the ALP group compared to the control group, while TTG levels were decreased in the ALP group. The ALP + CUR and ALP + nanomicelle-CUR groups had no significant difference in MDA levels compared to the control group. TAC levels were also significantly decreased in the ALP group compared to the control group, while the tissue TAC levels increased in the ALP + CUR and ALP + nanomicelle-CUR groups. The brain SOD level was significantly decreased in the ALP group compared to the control group, and the levels in the ALP + CUR and ALP + nanomicelle-CUR groups were not significantly different. The CUR and nanomicelle-CUR groups had no significant difference compared to the control group. The results suggest that the ALP group may have a higher SOD level than the CUR and nanomicelle-CUR groups.
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AIMS Neuroscience
How can nanomicelle-curcumin modulate aluminum phosphide-induced neurotoxicity?: Role of SIRT1/FOXO3 signaling pathway
<abstract>
<p>Aluminum phosphide (ALP) is among the most significant causes of brain toxicity and death in many countries. Curcumin (CUR), a major turmeric component, is a potent protective agent against many diseases, including brain toxicity. This study…
<p>Aluminum phosphide (ALP) is among the most significant causes of brain toxicity and death in many countries. Curcumin (CUR), a major turmeric component, is a potent protective agent against many diseases, including brain toxicity. This study…
How_can_nanomicelle-curcumin_modulate_aluminum_pho.pdf
1.3 MB
📋 Title: How can nanomicelle-curcumin modulate aluminum phosphide-induced neurotoxicity?: Role of SIRT1/FOXO3 signaling pathway
📥 Link: https://www.aimspress.com/article/doi/10.3934/Neuroscience.2023005
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📥 Link: https://www.aimspress.com/article/doi/10.3934/Neuroscience.2023005
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📋 Title: How can nanomicelle-curcumin modulate aluminum phosphide-induced neurotoxicity?: Role of SIRT1/FOXO3 signaling pathway
📥 Link: https://www.aimspress.com/article/doi/10.3934/Neuroscience.2023005
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📥 Link: https://www.aimspress.com/article/doi/10.3934/Neuroscience.2023005
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#NAIRG_Publication🧠
🩻 We aimed to predict Montreal Cognitive Assessment (MoCA) scores in Parkinson’s disease patients at year 4 using handcrafted radiomics (RF), deep (DF), and clinical (CF) features at year 0 (baseline) applied to hybrid machine learning systems (HMLSs)
📖 PDF file of this article is available in NAIRG channel
📋Title: Prediction of Cognitive Decline in Parkinson’s Disease Using Clinical and DAT SPECT Imaging Features, and Hybrid Machine Learning Systems
📥 Link :
https://www.mdpi.com/2075-4418/13/10/1691
📎 doi: https://doi.org/10.3390/diagnostics13101691
📎 Journal name:
Diagnostics 2023, 13(10), 1691;
📎 Authors:
Mahdi Hosseinzadeh
Arman Gorji
Ali Fathi Jouzdani
Seyed Masoud Rezaeijo
Arman Rahmim
Mohammad R. Salmanpour
📎 Result:
For the sole usage of RFs and DFs, ANOVA and MLP resulted in averaged accuracies of 59 ± 3% and 65 ± 4% for 5-fold cross-validation, respectively, with hold-out testing accuracies of 59 ± 1% and 56 ± 2%, respectively. For sole CFs, a higher performance of 77 ± 8% for 5-fold cross-validation and a hold-out testing performance of 82 + 2% were obtained from ANOVA and ETC. RF+DF obtained a performance of 64 ± 7%, with a hold-out testing performance of 59 ± 2% through ANOVA and XGBC. Usage of CF+RF, CF+DF
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🩻 We aimed to predict Montreal Cognitive Assessment (MoCA) scores in Parkinson’s disease patients at year 4 using handcrafted radiomics (RF), deep (DF), and clinical (CF) features at year 0 (baseline) applied to hybrid machine learning systems (HMLSs)
📖 PDF file of this article is available in NAIRG channel
📋Title: Prediction of Cognitive Decline in Parkinson’s Disease Using Clinical and DAT SPECT Imaging Features, and Hybrid Machine Learning Systems
📥 Link :
https://www.mdpi.com/2075-4418/13/10/1691
📎 doi: https://doi.org/10.3390/diagnostics13101691
📎 Journal name:
Diagnostics 2023, 13(10), 1691;
📎 Authors:
Mahdi Hosseinzadeh
Arman Gorji
Ali Fathi Jouzdani
Seyed Masoud Rezaeijo
Arman Rahmim
Mohammad R. Salmanpour
📎 Result:
For the sole usage of RFs and DFs, ANOVA and MLP resulted in averaged accuracies of 59 ± 3% and 65 ± 4% for 5-fold cross-validation, respectively, with hold-out testing accuracies of 59 ± 1% and 56 ± 2%, respectively. For sole CFs, a higher performance of 77 ± 8% for 5-fold cross-validation and a hold-out testing performance of 82 + 2% were obtained from ANOVA and ETC. RF+DF obtained a performance of 64 ± 7%, with a hold-out testing performance of 59 ± 2% through ANOVA and XGBC. Usage of CF+RF, CF+DF
@NAIRG_Channel
MDPI
Prediction of Cognitive Decline in Parkinson’s Disease Using Clinical and DAT SPECT Imaging Features, and Hybrid Machine Learning…
Background: We aimed to predict Montreal Cognitive Assessment (MoCA) scores in Parkinson’s disease patients at year 4 using handcrafted radiomics (RF), deep (DF), and clinical (CF) features at year 0 (baseline) applied to hybrid machine learning systems (HMLSs).…
diagnostics-13-01691-v2.pdf
1.6 MB
📋 Title :
Prediction of Cognitive Decline in Parkinson’s Disease Using Clinical and DAT SPECT Imaging Features, and Hybrid Machine Learning Systems
📥 Link:
https://www.mdpi.com/2075-4418/13/10/1691#
@NAIRG_Channel
Prediction of Cognitive Decline in Parkinson’s Disease Using Clinical and DAT SPECT Imaging Features, and Hybrid Machine Learning Systems
📥 Link:
https://www.mdpi.com/2075-4418/13/10/1691#
@NAIRG_Channel
📋 Title :
Prediction of Cognitive Decline in Parkinson’s Disease Using Clinical and DAT SPECT Imaging Features, and Hybrid Machine Learning Systems
📥 Link:
https://www.mdpi.com/2075-4418/13/10/1691#
@NAIRG_Channel
Prediction of Cognitive Decline in Parkinson’s Disease Using Clinical and DAT SPECT Imaging Features, and Hybrid Machine Learning Systems
📥 Link:
https://www.mdpi.com/2075-4418/13/10/1691#
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#NAIRG_Publication🧠
#Conferences
🩻Although the use of hand-crafted radiomics features (RF) has shown significant promise to improve diagnostic, prognostic, and treatment response assessments, employing deep features (DF) extracted from deep learning (DL) algorithms merits significant investigation in lung cancer disease. We aimed to employ RFs vs. DFs to predict recurrence-free survival (RFS) and overall survival (OS) using machine learning (ML) techniques in lung cancer.
📋 Title:
PET-CT Fusion Based Outcome Prediction in Lung Cancer using Deep and Handcrafted Radiomics Features and Machine Learning
📥 Link :
https://jnm.snmjournals.org/content/64/supplement_1/P1196.abstract
📎 Journal name:
Journal of Nuclear Medicine June 2023, 64 (supplement 1) P1196;
📎 Authors:
Arman Gorji
Ali Fathi Jouzdani
Nima Sanati
Mahdi Hosseinzadeh
Ali Mahboubisarighieh
Seyed Masoud Rezaeijo
Mehdi Maghsudi
Sara Moore
Leung Bonnie
Carlos Uribe
Cheryl Ho
Arman Rahmim
Mohammad R Salmanpour
📎 Result:
In RF framework, SR+ANOVA+MLP and VSMWLS+ANOVA+MLP resulted in MAEs of 506.7± 6.1 and 264.0±6.8 days to predict approximate death (OS) and approximate recurrence time (RFS) while we arrived at the lowest MSEs of 430.3±10.2 and 250.5±10.2 using DF supplied to LP_SR+ANOVA+MLP and CT+MRMR+ HistGB, respectively. In predictions of time to events such as OS and RFS, Wavelet+PCA+RadSF and NSCT_SR+PCA+RadSF linked with DFs obtained c-indexes of 0.59±0.03 and 0.61±0.01, while the highest c-indexes of 0.64 ±0.03 and 0.61±0.05 were obtained by RFs followed by CBF+PCA+RadSF and VSMWLS+PCA+RadSF, respectively.
@NAIRG_Channel
#Conferences
🩻Although the use of hand-crafted radiomics features (RF) has shown significant promise to improve diagnostic, prognostic, and treatment response assessments, employing deep features (DF) extracted from deep learning (DL) algorithms merits significant investigation in lung cancer disease. We aimed to employ RFs vs. DFs to predict recurrence-free survival (RFS) and overall survival (OS) using machine learning (ML) techniques in lung cancer.
📋 Title:
PET-CT Fusion Based Outcome Prediction in Lung Cancer using Deep and Handcrafted Radiomics Features and Machine Learning
📥 Link :
https://jnm.snmjournals.org/content/64/supplement_1/P1196.abstract
📎 Journal name:
Journal of Nuclear Medicine June 2023, 64 (supplement 1) P1196;
📎 Authors:
Arman Gorji
Ali Fathi Jouzdani
Nima Sanati
Mahdi Hosseinzadeh
Ali Mahboubisarighieh
Seyed Masoud Rezaeijo
Mehdi Maghsudi
Sara Moore
Leung Bonnie
Carlos Uribe
Cheryl Ho
Arman Rahmim
Mohammad R Salmanpour
📎 Result:
In RF framework, SR+ANOVA+MLP and VSMWLS+ANOVA+MLP resulted in MAEs of 506.7± 6.1 and 264.0±6.8 days to predict approximate death (OS) and approximate recurrence time (RFS) while we arrived at the lowest MSEs of 430.3±10.2 and 250.5±10.2 using DF supplied to LP_SR+ANOVA+MLP and CT+MRMR+ HistGB, respectively. In predictions of time to events such as OS and RFS, Wavelet+PCA+RadSF and NSCT_SR+PCA+RadSF linked with DFs obtained c-indexes of 0.59±0.03 and 0.61±0.01, while the highest c-indexes of 0.64 ±0.03 and 0.61±0.05 were obtained by RFs followed by CBF+PCA+RadSF and VSMWLS+PCA+RadSF, respectively.
@NAIRG_Channel
#Conferences
📋 Title :
PET-CT Fusion Based Outcome Prediction in Lung Cancer using Deep and Handcrafted Radiomics Features and Machine Learning
📥 Link:
https://jnm.snmjournals.org/content/64/supplement_1/P1196.abstract
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📋 Title :
PET-CT Fusion Based Outcome Prediction in Lung Cancer using Deep and Handcrafted Radiomics Features and Machine Learning
📥 Link:
https://jnm.snmjournals.org/content/64/supplement_1/P1196.abstract
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#NAIRG_Publication🧠
📝 Paraquat (PQ) is a nonselective herbicide that induces oxidative reactions and multiple-organ failure on exposure. Crocin, a carotenoid obtained from saffron, has demonstrated many therapeutic effects against neural conditions because of its antioxidant properties. In this study, 30 male Wistar rats were divided into 6 groups to evaluate the protective effects of crocin and crocin-loaded niosomes (NC) against PQ in the brain. The levels of total antioxidant capacity (TAC), lipid peroxidation (LPO), total thiol groups (TTG), superoxide dismutase (SOD), and catalase (CAT) activity were measured as the markers of redox status.
📖 PDF file of this article is available in NAIRG channel
📋 Title: Neuroprotective effects of crocin and crocin-loaded niosomes against the paraquat-induced oxidative brain damage in rats
📥 Link :
https://www.degruyter.com/document/doi/10.1515/biol-2022-0468/html
📎 doi:
https://doi.org/10.1515/biol-2022-0468
📎 Journal name:
Published by De Gruyter Open Access September 14, 2022
📎 Authors:
Afsoon Daneshvar
Ali Fathi Jouzdani
Farzin Firozian
Sara Soleimani Asl
Mojdeh Mohammadi and Akram Ranjbar
📎 Result:
1)The LPO level revealed that PQ induced a significant increase in LPO in the brain compared to control (P < 0.0001).
2)Treatments with crocin or NC resulted in minor differences in TAC levels compared with control, which was not significant.
3) crocin had a significant effect on TTG compared to control (P < 0.01).
4) The assessment of CAT activity revealed a significant difference between the control and all other groups
5)The assessment of SOD activity revealed a significant difference between the control and PQ (P < 0.01) and NC (P < 0.001) groups.
6)Histological evaluations revealed that the PQ-induced rats displayed a significant decrease in cell density in the CA1 region of the hippocampus compared to normal , crocin and NC (P < 0.001) groups. Treatments with crocin (P < 0.01) and NC (P < 0.001) plus PQ led to an enhancement in cell density of CA1 compared to the PQ group. Although treatment with crocin or NC showed no difference in cell count, the bulk and nanoformulations of crocin presented different effect levels in PQ-toxicity rats . No difference was seen between the crocin and NC groups compared to the control group
@NAIRG_Channel
📝 Paraquat (PQ) is a nonselective herbicide that induces oxidative reactions and multiple-organ failure on exposure. Crocin, a carotenoid obtained from saffron, has demonstrated many therapeutic effects against neural conditions because of its antioxidant properties. In this study, 30 male Wistar rats were divided into 6 groups to evaluate the protective effects of crocin and crocin-loaded niosomes (NC) against PQ in the brain. The levels of total antioxidant capacity (TAC), lipid peroxidation (LPO), total thiol groups (TTG), superoxide dismutase (SOD), and catalase (CAT) activity were measured as the markers of redox status.
📖 PDF file of this article is available in NAIRG channel
📋 Title: Neuroprotective effects of crocin and crocin-loaded niosomes against the paraquat-induced oxidative brain damage in rats
📥 Link :
https://www.degruyter.com/document/doi/10.1515/biol-2022-0468/html
📎 doi:
https://doi.org/10.1515/biol-2022-0468
📎 Journal name:
Published by De Gruyter Open Access September 14, 2022
📎 Authors:
Afsoon Daneshvar
Ali Fathi Jouzdani
Farzin Firozian
Sara Soleimani Asl
Mojdeh Mohammadi and Akram Ranjbar
📎 Result:
1)The LPO level revealed that PQ induced a significant increase in LPO in the brain compared to control (P < 0.0001).
2)Treatments with crocin or NC resulted in minor differences in TAC levels compared with control, which was not significant.
3) crocin had a significant effect on TTG compared to control (P < 0.01).
4) The assessment of CAT activity revealed a significant difference between the control and all other groups
5)The assessment of SOD activity revealed a significant difference between the control and PQ (P < 0.01) and NC (P < 0.001) groups.
6)Histological evaluations revealed that the PQ-induced rats displayed a significant decrease in cell density in the CA1 region of the hippocampus compared to normal , crocin and NC (P < 0.001) groups. Treatments with crocin (P < 0.01) and NC (P < 0.001) plus PQ led to an enhancement in cell density of CA1 compared to the PQ group. Although treatment with crocin or NC showed no difference in cell count, the bulk and nanoformulations of crocin presented different effect levels in PQ-toxicity rats . No difference was seen between the crocin and NC groups compared to the control group
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10.1515_biol-2022-0468.pdf
2 MB
📋 Title:
Neuroprotective effects of crocin and crocin-loaded niosomes against the paraquat-induced oxidative brain damage in rats
📎 doi: https://doi.org/10.1515/biol-2022-0468
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Neuroprotective effects of crocin and crocin-loaded niosomes against the paraquat-induced oxidative brain damage in rats
📎 doi: https://doi.org/10.1515/biol-2022-0468
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📋 Title:
Neuroprotective effects of crocin and crocin-loaded niosomes against the paraquat-induced oxidative brain damage in rats
📎 doi: https://doi.org/10.1515/biol-2022-0468
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Neuroprotective effects of crocin and crocin-loaded niosomes against the paraquat-induced oxidative brain damage in rats
📎 doi: https://doi.org/10.1515/biol-2022-0468
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