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Effect of a Cerebral Protection Device on Brain Lesions Following Transcatheter Aortic #Valve Implantation in Patients With Severe Aortic Stenosis
The CLEAN- #TAVI Randomized Clinical Trial
http://jama.jamanetwork.com/mobile/article.aspx?articleid=2542633
Conclusions and Relevance Among patients with severe aortic stenosis undergoing TAVI, the use of a cerebral protection device reduced the frequency of ischemic cerebral lesions in potentially protected regions. Larger studies are needed to assess the effect of cerebral protection device use on neurological and cognitive function after TAVI and to devise methods that will provide more complete coverage of the brain to prevent new lesions.
Effect of a Cerebral Protection Device on Brain Lesions Following Transcatheter Aortic #Valve Implantation in Patients With Severe Aortic Stenosis
The CLEAN- #TAVI Randomized Clinical Trial
http://jama.jamanetwork.com/mobile/article.aspx?articleid=2542633
Conclusions and Relevance Among patients with severe aortic stenosis undergoing TAVI, the use of a cerebral protection device reduced the frequency of ischemic cerebral lesions in potentially protected regions. Larger studies are needed to assess the effect of cerebral protection device use on neurological and cognitive function after TAVI and to devise methods that will provide more complete coverage of the brain to prevent new lesions.
Jamanetwork
Cerebral Protection Device Effects on Brain Lesions After TAVI
This randomized clinical trial compares the effects of use vs nonuse of a cerebral embolic protection device during transcatheter aortic valve implantation (TAVI) on MRI-detected brain lesions in patients with severe aortic stenosis undergoing TAVI.
#Warfarin and Antiplatelet Therapy Versus Warfarin Alone for Treating Patients With Atrial Fibrillation Undergoing Transcatheter Aortic #Valve Replacement
http://www.sciencedirect.com/science/article/pii/S1936879816309347?via%3Dihub
In TAVR recipients prescribed VKA therapy for AF, concomitant antiplatelet therapy use appears not to reduce the incidence of stroke, major adverse cardiovascular events, or death, while increasing the risk of major or life-threatening bleeding.
http://www.sciencedirect.com/science/article/pii/S1936879816309347?via%3Dihub
In TAVR recipients prescribed VKA therapy for AF, concomitant antiplatelet therapy use appears not to reduce the incidence of stroke, major adverse cardiovascular events, or death, while increasing the risk of major or life-threatening bleeding.
Association Between Transcatheter Aortic #Valve Replacement and Subsequent Infective #Endocarditis and In-Hospital Death
http://jama.jamanetwork.com/mobile/article.aspx?articleid=2552209
Conclusions and Relevance Among patients undergoing TAVR, younger age, male sex, history of diabetes mellitus, and moderate to severe residual aortic regurgitation were significantly associated with an increased risk of infective endocarditis. Patients who developed endocarditis had high rates of in-hospital mortality and 2-year mortality.
http://jama.jamanetwork.com/mobile/article.aspx?articleid=2552209
Conclusions and Relevance Among patients undergoing TAVR, younger age, male sex, history of diabetes mellitus, and moderate to severe residual aortic regurgitation were significantly associated with an increased risk of infective endocarditis. Patients who developed endocarditis had high rates of in-hospital mortality and 2-year mortality.
Jamanetwork
Transcatheter Aortic Valve Replacement, Infective Endocarditis, and Death
This cohort study uses international registry data to characterize clinical risk factors, microbiology, and outcomes of patients who developed infective endocarditis following transcatheter aortic valve replacement.
Prognosis after #surgical replacement with a bioprosthetic aortic #valve in patients with severe symptomatic aortic stenosis: systematic review of observational studies
http://www.bmj.com/content/354/bmj.i5065
Conclusion Patients with severe symptomatic aortic stenosis undergoing SAVR with a bioprosthetic valve can expect only slightly lower survival than those without aortic stenosis, and a low incidence of stroke and, up to 10 years, of structural valve deterioration. The rate of deterioration increases rapidly after 10 years, and particularly after 15 years.
http://www.bmj.com/content/354/bmj.i5065
Conclusion Patients with severe symptomatic aortic stenosis undergoing SAVR with a bioprosthetic valve can expect only slightly lower survival than those without aortic stenosis, and a low incidence of stroke and, up to 10 years, of structural valve deterioration. The rate of deterioration increases rapidly after 10 years, and particularly after 15 years.
The BMJ
Prognosis after surgical replacement with a bioprosthetic aortic valve in patients with severe symptomatic aortic stenosis: systematic…
Objective To determine the frequency of survival, stroke, atrial fibrillation, structural valve deterioration, and length of hospital stay after surgical replacement of an aortic valve (SAVR) with a bioprosthetic valve in patients with severe symptomatic…
#Aspirin with or without #Clopidogrel after Transcatheter Aortic- #Valve Implantation
https://2medical.news/2020/09/03/aspirin-with-or-without-clopidogrel-after-transcatheter-aortic-valve-implantation/
The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has not been well studied.. ..A total of 331 patients were assigned to receive aspirin alone and 334 were assigned to receive aspirin plus clopidogrel. A bleeding event occurred in 50 patients (15.1%) receiving …
https://2medical.news/2020/09/03/aspirin-with-or-without-clopidogrel-after-transcatheter-aortic-valve-implantation/
The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has not been well studied.. ..A total of 331 patients were assigned to receive aspirin alone and 334 were assigned to receive aspirin plus clopidogrel. A bleeding event occurred in 50 patients (15.1%) receiving …