Strategies to Optimize #Nephrolithiasis Emergency Care (STONE): Prospective Evaluation of an Emergency Department Clinical Pathway
https://2medical.news/2021/11/07/strategies-to-optimize-nephrolithiasis-emergency-care-stone-prospective-evaluation-of-an-emergency-department-clinical-pathway/
https://2medical.news/2021/11/07/strategies-to-optimize-nephrolithiasis-emergency-care-stone-prospective-evaluation-of-an-emergency-department-clinical-pathway/
2Medical.News
Strategies to Optimize #Nephrolithiasis Emergency Care (STONE): Prospective Evaluation of an Emergency Department Clinical Pathway
To convene a multi-disciplinary panel to develop a pathway for Emergency Department (ED) patients with suspected nephrolithiasis and then prospectively evaluate its effect on patient care. Material…
Association Between #Melanoma Detected During Routine Skin Checks and Mortality
https://2medical.news/2021/11/07/association-between-melanoma-detected-during-routine-skin-checks-and-mortality/
https://2medical.news/2021/11/07/association-between-melanoma-detected-during-routine-skin-checks-and-mortality/
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Association Between #Melanoma Detected During Routine Skin Checks and Mortality
Are melanomas diagnosed through routine skin checks (a proxy for skin cancer screening) associated with reduced melanoma-specific and all-cause mortality? Findings This population-based cohort stud…
A class II MHC-targeted vaccine elicits immunity against #SARS-CoV-2 and its variants
https://2medical.news/2021/11/08/a-class-ii-mhc-targeted-vaccine-elicits-immunity-against-sars-cov-2-and-its-variants/
https://2medical.news/2021/11/08/a-class-ii-mhc-targeted-vaccine-elicits-immunity-against-sars-cov-2-and-its-variants/
2Medical.News
A class II MHC-targeted vaccine elicits immunity against #SARS-CoV-2 and its variants
Vaccines remain the best hope of curtailing SARS-CoV-2 transmission, morbidity, and mortality. Currently available vaccines require cold storage and sophisticated manufacturing capacity, complicati…
EDP-305 in patients with #NASH: A phase II double-blind placebo-controlled dose-ranging study
https://2medical.news/2021/11/08/edp-305-in-patients-with-nash-a-phase-ii-double-blind-placebo-controlled-dose-ranging-study/
https://2medical.news/2021/11/08/edp-305-in-patients-with-nash-a-phase-ii-double-blind-placebo-controlled-dose-ranging-study/
2Medical.News
EDP-305 in patients with #NASH: A phase II double-blind placebo-controlled dose-ranging study
•EDP-305 is an oral farnesoid X receptor (FXR) agonist being developed to treat nonalcoholic steatohepatitis (NASH).•In a randomized, placebo-controlled study, 12-week study, EDP-305 reduced ALT le…
Discovery of Autoantibodies Targeting #Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology
https://2medical.news/2021/11/09/discovery-of-autoantibodies-targeting-nephrin-in-minimal-change-disease-supports-a-novel-autoimmune-etiology/
https://2medical.news/2021/11/09/discovery-of-autoantibodies-targeting-nephrin-in-minimal-change-disease-supports-a-novel-autoimmune-etiology/
2Medical.News
Discovery of Autoantibodies Targeting #Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology
Failure of the glomerular filtration barrier, primarily by loss of slit diaphragm architecture, underlies nephrotic syndrome in minimal change disease. The etiology remains unknown. The efficacy of…
Genome-wide analysis of 53,400 people with #irritable bowel syndrome highlights shared genetic pathways with #mood and #anxiety disorders
https://2medical.news/2021/11/09/genome-wide-analysis-of-53400-people-with-irritable-bowel-syndrome-highlights-shared-genetic-pathways-with-mood-and-anxiety-disorders/
https://2medical.news/2021/11/09/genome-wide-analysis-of-53400-people-with-irritable-bowel-syndrome-highlights-shared-genetic-pathways-with-mood-and-anxiety-disorders/
2Medical.News
Genome-wide analysis of 53,400 people with #irritable bowel syndrome highlights shared genetic pathways with #mood and #anxiety…
Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive…
Disruption of autophagy by increased #5-HT alters gut microbiota and enhances susceptibility to experimental colitis and #Crohn’s disease
https://2medical.news/2021/11/10/disruption-of-autophagy-by-increased-5-ht-alters-gut-microbiota-and-enhances-susceptibility-to-experimental-colitis-and-crohns-disease/
https://2medical.news/2021/11/10/disruption-of-autophagy-by-increased-5-ht-alters-gut-microbiota-and-enhances-susceptibility-to-experimental-colitis-and-crohns-disease/
2Medical.News
Disruption of autophagy by increased #5-HT alters gut microbiota and enhances susceptibility to experimental colitis and #Crohn’s…
Autophagy, an essential intracellular recycling process, is linked to the pathogenesis of various diseases including Crohn’s disease (CD). Factors that lead to the development of impaired autophagy…
Long-term mortality of patients with #osteoarthritis after #joint replacement: Prognostic value of pre- and postoperative pain and function
https://2medical.news/2021/11/10/long-term-mortality-of-patients-with-osteoarthritis-after-joint-replacement-prognostic-value-of-pre-and-postoperative-pain-and-function/
https://2medical.news/2021/11/10/long-term-mortality-of-patients-with-osteoarthritis-after-joint-replacement-prognostic-value-of-pre-and-postoperative-pain-and-function/
2Medical.News
Long-term mortality of patients with #osteoarthritis after #joint replacement: Prognostic value of pre- and postoperative pain…
To investigate whether osteoarthritis (OA)–specific assessment values (i.e. Western Ontario and McMaster University Osteoarthritis Index [WOMAC]) and generic pain and function (visual analog scale …
Country roads, take me home… to my friends: How #intelligence, population density, and friendship affect modern #happiness
https://2medical.news/2021/11/11/country-roads-take-me-home-to-my-friends-how-intelligence-population-density-and-friendship-affect-modern-happiness/
https://2medical.news/2021/11/11/country-roads-take-me-home-to-my-friends-how-intelligence-population-density-and-friendship-affect-modern-happiness/
2Medical.News
Country roads, take me home… to my friends: How #intelligence, population density, and friendship affect modern #happiness
We propose the savanna theory of happiness, which suggests that it is not only the current consequences of a given situation but also its ancestral consequences that affect individuals’ life satisf…
A novel adverse effect of the BNT162b2 mRNA vaccine: First episode of acute #mania with #psychotic features
https://2medical.news/2021/11/11/a-novel-adverse-effect-of-the-bnt162b2-mrna-vaccine-first-episode-of-acute-mania-with-psychotic-features/
https://2medical.news/2021/11/11/a-novel-adverse-effect-of-the-bnt162b2-mrna-vaccine-first-episode-of-acute-mania-with-psychotic-features/
2Medical.News
A novel adverse effect of the BNT162b2 mRNA vaccine: First episode of acute #mania with #psychotic features
Dear Editor;A vaccine against SARS-CoV2, which is causing the global COVID-19 pandemic, was developed for the first-time using mRNA technology. Although the short- and long-term side-effects of the…
2021 #Dietary Guidance to Improve #Cardiovascular Health: A Scientific Statement From the American Heart Association
https://2medical.news/2021/11/12/2021-dietary-guidance-to-improve-cardiovascular-health-a-scientific-statement-from-the-american-heart-association/
https://2medical.news/2021/11/12/2021-dietary-guidance-to-improve-cardiovascular-health-a-scientific-statement-from-the-american-heart-association/
2Medical.News
2021 #Dietary Guidance to Improve #Cardiovascular Health: A Scientific Statement From the American Heart Association
Poor diet quality is strongly associated with elevated risk of cardiovascular disease morbidity and mortality. This scientific statement emphasizes the importance of dietary patterns beyond individ…
Serial Assessment of High-Sensitivity Cardiac #Troponin and the Effect of #Dapagliflozin in Patients with Heart #Failure with Reduced Ejection Fraction: An Analysis of the DAPA-HF Trial
https://2medical.news/2021/11/12/serial-assessment-of-high-sensitivity-cardiac-troponin-and-the-effect-of-dapagliflozin-in-patients-with-heart-failure-with-reduced-ejection-fraction-an-analysis-of-the-dapa-hf-trial/
https://2medical.news/2021/11/12/serial-assessment-of-high-sensitivity-cardiac-troponin-and-the-effect-of-dapagliflozin-in-patients-with-heart-failure-with-reduced-ejection-fraction-an-analysis-of-the-dapa-hf-trial/
2Medical.News
Serial Assessment of High-Sensitivity Cardiac #Troponin and the Effect of #Dapagliflozin in Patients with Heart #Failure with Reduced…
Circulating high-sensitivity cardiac troponin T (hsTnT) predominantly reflects myocardial injury, and higher levels are associated with a higher risk of worsening heart failure (HF) and death in pa…
Charting host-microbe co-metabolism in #skin #aging and application to metagenomics data
https://2medical.news/2021/11/13/charting-host-microbe-co-metabolism-in-skin-aging-and-application-to-metagenomics-data/
https://2medical.news/2021/11/13/charting-host-microbe-co-metabolism-in-skin-aging-and-application-to-metagenomics-data/
2Medical.News
Charting host-microbe co-metabolism in #skin #aging and application to metagenomics data
During aging of human skin, a number of intrinsic and extrinsic factors cause the alteration of the skin’s structure, function and cutaneous physiology. Many studies have investigated the influence…
Experiences of Work-Family Conflict and #Mental Health Symptoms by Gender Among Physician Parents During the #COVID-19 Pandemic
https://2medical.news/2021/11/13/experiences-of-work-family-conflict-and-mental-health-symptoms-by-gender-among-physician-parents-during-the-covid-19-pandemic/
https://2medical.news/2021/11/13/experiences-of-work-family-conflict-and-mental-health-symptoms-by-gender-among-physician-parents-during-the-covid-19-pandemic/
2Medical.News
Experiences of Work-Family Conflict and #Mental Health Symptoms by Gender Among Physician Parents During the #COVID-19 Pandemic
The COVID-19 pandemic has placed increased strain on health care workers and disrupted childcare and schooling arrangements in unprecedented ways. As substantial gender inequalities existed in medi…
Downregulation of Erythrocyte miR-210 Induces #Endothelial Dysfunction in Type 2 #Diabetes
https://2medical.news/2021/11/14/downregulation-of-erythrocyte-mir-210-induces-endothelial-dysfunction-in-type-2-diabetes/
https://2medical.news/2021/11/14/downregulation-of-erythrocyte-mir-210-induces-endothelial-dysfunction-in-type-2-diabetes/
2Medical.News
Downregulation of Erythrocyte miR-210 Induces #Endothelial Dysfunction in Type 2 #Diabetes
Red blood cells (RBCs) act as mediators of vascular injury in type 2 diabetes mellitus (T2DM). miR-210 plays a protective role in cardiovascular homeostasis and is decreased in whole blood of T2DM …
Serum Nonesterified #Fatty Acids and Incident #Stroke: The CHS
https://2medical.news/2021/11/14/serum-nonesterified-fatty-acids-and-incident-stroke-the-chs/
https://2medical.news/2021/11/14/serum-nonesterified-fatty-acids-and-incident-stroke-the-chs/
2Medical.News
Serum Nonesterified #Fatty Acids and Incident #Stroke: The CHS
Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies. We evaluated the associations betwee…
Transparency of COVID-19 vaccine trials: decisions without data
https://2medical.news/2021/11/15/transparency-of-covid-19-vaccine-trials-decisions-without-data/
https://2medical.news/2021/11/15/transparency-of-covid-19-vaccine-trials-decisions-without-data/
2Medical.News
Transparency of COVID-19 vaccine trials: decisions without data
Summary boxData transparency has become a well-established norm in biomedical research, and is especially important for broadly used public health interventions like COVID-19 vaccines. Tax payers h…
Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease
https://2medical.news/2021/11/15/secondary-antibiotic-prophylaxis-for-latent-rheumatic-heart-disease/
https://2medical.news/2021/11/15/secondary-antibiotic-prophylaxis-for-latent-rheumatic-heart-disease/
2Medical.News
Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease
Rheumatic heart disease affects more than 40.5 million people worldwide and results in 306,000 deaths annually. Echocardiographic screening detects rheumatic heart disease at an early, latent stage…
Transmission of SARS-CoV-2 Delta Variant Among Vaccinated Healthcare Workers, Vietnam
https://2medical.news/2021/11/16/transmission-of-sars-cov-2-delta-variant-among-vaccinated-healthcare-workers-vietnam/
https://2medical.news/2021/11/16/transmission-of-sars-cov-2-delta-variant-among-vaccinated-healthcare-workers-vietnam/
2Medical.News
Transmission of SARS-CoV-2 Delta Variant Among Vaccinated Healthcare Workers, Vietnam
Background: Data on breakthrough SARS-CoV-2 Delta variant infections are limited. Methods: We studied breakthrough infections among healthcare workers of a major infectious diseases hospital in Vie…
The Self in the Mind’s Eye: Revealing How We Truly See Ourselves Through Reverse Correlation
https://2medical.news/2021/11/16/the-self-in-the-minds-eye-revealing-how-we-truly-see-ourselves-through-reverse-correlation/
https://2medical.news/2021/11/16/the-self-in-the-minds-eye-revealing-how-we-truly-see-ourselves-through-reverse-correlation/
2Medical.News
The Self in the Mind’s Eye: Revealing How We Truly See Ourselves Through Reverse Correlation
Is there a way to visually depict the image people “see” of themselves in their minds’ eyes? And if so, what can these mental images tell us about ourselves? We used a computational reverse-correla…
Discovery of a novel pseudo β-hairpin structure of N-truncated amyloid-β for use as a vaccine against Alzheimer’s disease
https://2medical.news/2021/11/17/discovery-of-a-novel-pseudo-%CE%B2-hairpin-structure-of-n-truncated-amyloid-%CE%B2-for-use-as-a-vaccine-against-alzheimers-disease/
https://2medical.news/2021/11/17/discovery-of-a-novel-pseudo-%CE%B2-hairpin-structure-of-n-truncated-amyloid-%CE%B2-for-use-as-a-vaccine-against-alzheimers-disease/
2Medical.News
Discovery of a novel pseudo β-hairpin structure of N-truncated amyloid-β for use as a vaccine against Alzheimer’s disease
One of the hallmarks of Alzheimer’s disease (AD) are deposits of amyloid-beta (Aβ) protein in amyloid plaques in the brain. The Aβ peptide exists in several forms, including full-length Aβ1-42 and …