An #Egg-Derived Sulfated N-Acetyllactosamine Glycan Is an Antigenic Decoy of Influenza Virus #Vaccines
https://2medical.news/2021/07/07/an-egg-derived-sulfated-n-acetyllactosamine-glycan-is-an-antigenic-decoy-of-influenza-virus-vaccines/
https://2medical.news/2021/07/07/an-egg-derived-sulfated-n-acetyllactosamine-glycan-is-an-antigenic-decoy-of-influenza-virus-vaccines/
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An #Egg-Derived Sulfated N-Acetyllactosamine Glycan Is an Antigenic Decoy of Influenza Virus #Vaccines
Influenza viruses grown in eggs for the purposes of vaccine generation often acquire mutations during egg adaptation or possess different glycosylation patterns than viruses circulating among human…
A 5,000-year-old hunter-gatherer already plagued by #Yersinia pestis
https://2medical.news/2021/07/07/a-5000-year-old-hunter-gatherer-already-plagued-by-yersinia-pestis/
https://2medical.news/2021/07/07/a-5000-year-old-hunter-gatherer-already-plagued-by-yersinia-pestis/
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A 5,000-year-old hunter-gatherer already plagued by #Yersinia pestis
A 5,000-year-old Yersinia pestis genome (RV 2039) is reconstructed from a hunter-fisher-gatherer (5300–5050 cal BP) buried at Riņņukalns, Latvia. RV 2039 is the first in a series of ancient strains…
Prevalence of Nonradiographic #Sacroiliitis in Patients With Psoriatic #Arthritis: A Real-life Observational Study
https://2medical.news/2021/07/08/prevalence-of-nonradiographic-sacroiliitis-in-patients-with-psoriatic-arthritis-a-real-life-observational-study/
https://2medical.news/2021/07/08/prevalence-of-nonradiographic-sacroiliitis-in-patients-with-psoriatic-arthritis-a-real-life-observational-study/
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Prevalence of Nonradiographic #Sacroiliitis in Patients With Psoriatic #Arthritis: A Real-life Observational Study
To establish the prevalence of nonradiographic sacroiliitis within a real-life sample of patients with psoriatic arthritis (PsA), using pelvic radiographs and magnetic resonance imaging (MRI) of sa…
T-Type Ca2+ Enhancer SAK3 Activates CaMKII and Proteasome Activities in #Lewy Body Dementia Mice Model
https://2medical.news/2021/07/08/t-type-ca2-enhancer-sak3-activates-camkii-and-proteasome-activities-in-lewy-body-dementia-mice-model/
https://2medical.news/2021/07/08/t-type-ca2-enhancer-sak3-activates-camkii-and-proteasome-activities-in-lewy-body-dementia-mice-model/
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T-Type Ca2+ Enhancer SAK3 Activates CaMKII and Proteasome Activities in #Lewy Body Dementia Mice Model
Lewy bodies are pathological characteristics of Lewy body dementia (LBD) and are composed of α-synuclein (α-Syn), which is mostly degraded via the ubiquitin–proteasome system. More importantly, 26S…
#Proton pump inhibitors and risk of #colorectal cancer
https://2medical.news/2021/07/09/proton-pump-inhibitors-and-risk-of-colorectal-cancer/
https://2medical.news/2021/07/09/proton-pump-inhibitors-and-risk-of-colorectal-cancer/
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#Proton pump inhibitors and risk of #colorectal cancer
To determine whether proton pump inhibitors (PPIs) are associated with an increased risk of colorectal cancer, compared with histamine-2 receptor antagonists (H2RAs). Design The United Kingdom Clin…
A critical role of hepatic #GABA in the metabolic dysfunction and #hyperphagia of #obesity
https://2medical.news/2021/07/09/a-critical-role-of-hepatic-gaba-in-the-metabolic-dysfunction-and-hyperphagia-of-obesity/
https://2medical.news/2021/07/09/a-critical-role-of-hepatic-gaba-in-the-metabolic-dysfunction-and-hyperphagia-of-obesity/
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A critical role of hepatic #GABA in the metabolic dysfunction and #hyperphagia of #obesity
Hepatic lipid accumulation is a hallmark of type II diabetes (T2D) associated with hyperinsulinemia, insulin resistance, and hyperphagia. Hepatic synthesis of GABA, catalyzed by GABA-transaminase (…
#Time-restricted feeding protects the blood #pressure circadian rhythm in #diabetic mice
https://2medical.news/2021/07/10/time-restricted-feeding-protects-the-blood-pressure-circadian-rhythm-in-diabetic-mice/
https://2medical.news/2021/07/10/time-restricted-feeding-protects-the-blood-pressure-circadian-rhythm-in-diabetic-mice/
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#Time-restricted feeding protects the blood #pressure circadian rhythm in #diabetic mice
The quantity and quality of food intake have been considered crucial for peoples’ wellness. Only recently has it become appreciated that the timing of food intake is also critical. Nondipping…
Intact Fasting #Insulin Identifies Nonalcoholic Fatty #Liver Disease in Patients Without Diabetes
https://2medical.news/2021/07/10/intact-fasting-insulin-identifies-nonalcoholic-fatty-liver-disease-in-patients-without-diabetes/
https://2medical.news/2021/07/10/intact-fasting-insulin-identifies-nonalcoholic-fatty-liver-disease-in-patients-without-diabetes/
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Intact Fasting #Insulin Identifies Nonalcoholic Fatty #Liver Disease in Patients Without Diabetes
Patients with nonalcoholic fatty liver disease (NAFLD) are characterized by insulin resistance and hyperinsulinism. However, insulin resistance measurements have not been shown to be good diagnosti…
Incidence of #liver-related morbidity and mortality in a population cohort of non-alcoholic fatty liver disease
https://2medical.news/2021/07/11/incidence-of-liver-related-morbidity-and-mortality-in-a-population-cohort-of-non-alcoholic-fatty-liver-disease/
https://2medical.news/2021/07/11/incidence-of-liver-related-morbidity-and-mortality-in-a-population-cohort-of-non-alcoholic-fatty-liver-disease/
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Incidence of #liver-related morbidity and mortality in a population cohort of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) increases morbidity and mortality. However, patients in biopsy-based cohorts are highly selected and the absolute risks of liver- and non-liver outcomes in…
#Social Health and #Cardiovascular Disease Risk Factors: A cross-sectional study in a healthy older adult population
https://2medical.news/2021/07/11/social-health-and-cardiovascular-disease-risk-factors-a-cross-sectional-study-in-a-healthy-older-adult-population/
https://2medical.news/2021/07/11/social-health-and-cardiovascular-disease-risk-factors-a-cross-sectional-study-in-a-healthy-older-adult-population/
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#Social Health and #Cardiovascular Disease Risk Factors: A cross-sectional study in a healthy older adult population
Poor social health is a risk factor for cardiovascular disease (CVD), however an in-depth exploration of the link through CVD risk factors is lacking. AimTo examine the relationship between social …
The effect of #depression status change on daily #cigarette smoking amount according to sex: an eleven-year follow up study of the Korea Welfare Panel Study
https://2medical.news/2021/07/12/the-effect-of-depression-status-change-on-daily-cigarette-smoking-amount-according-to-sex-an-eleven-year-follow-up-study-of-the-korea-welfare-panel-study/
https://2medical.news/2021/07/12/the-effect-of-depression-status-change-on-daily-cigarette-smoking-amount-according-to-sex-an-eleven-year-follow-up-study-of-the-korea-welfare-panel-study/
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The effect of #depression status change on daily #cigarette smoking amount according to sex: an eleven-year follow up study of…
In the past decade, the Korean smoking rate has only decreased by 3%, despite several smoking control policies. There is a need for such policies to take smokers’ psychological characteristics into…
#Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo
https://2medical.news/2021/07/12/psilocybin-induces-rapid-and-persistent-growth-of-dendritic-spines-in-frontal-cortex-in-vivo/
https://2medical.news/2021/07/12/psilocybin-induces-rapid-and-persistent-growth-of-dendritic-spines-in-frontal-cortex-in-vivo/
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#Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo
Psilocybin ameliorates stress-related behavioral deficit in mice•Psilocybin increases spine density and spine size in frontal cortical pyramidal cells•Psilocybin-evoked structural remodeling is per…
Dose-Response Meta-Analysis on #Tooth Loss With the Risk of #Cognitive Impairment and #Dementia
https://2medical.news/2021/07/13/dose-response-meta-analysis-on-tooth-loss-with-the-risk-of-cognitive-impairment-and-dementia/
https://2medical.news/2021/07/13/dose-response-meta-analysis-on-tooth-loss-with-the-risk-of-cognitive-impairment-and-dementia/
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Dose-Response Meta-Analysis on #Tooth Loss With the Risk of #Cognitive Impairment and #Dementia
To quantify the dose-response associations between tooth loss and risk of cognitive impairment and dementia. DesignLongitudinal studies that examined the association between tooth loss and cognitiv…
SO-25 Global rise in early-onset #colorectal cancer: An association with #antibiotic consumption?
https://2medical.news/2021/07/13/so-25-global-rise-in-early-onset-colorectal-cancer-an-association-with-antibiotic-consumption/
https://2medical.news/2021/07/13/so-25-global-rise-in-early-onset-colorectal-cancer-an-association-with-antibiotic-consumption/
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SO-25 Global rise in early-onset #colorectal cancer: An association with #antibiotic consumption?
Since the late 1980s, global antibiotic consumption and colorectal cancer (CRC) rates in those aged less than 50 years have soared. As the gut microbiome modulates many human processes, significant…
Gut #microbiome heritability is nearly universal but environmentally contingent
https://2medical.news/2021/07/14/gut-microbiome-heritability-is-nearly-universal-but-environmentally-contingent/
https://2medical.news/2021/07/14/gut-microbiome-heritability-is-nearly-universal-but-environmentally-contingent/
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Gut #microbiome heritability is nearly universal but environmentally contingent
Baboons inform on human gut microbiotaCommensal bacteria are found throughout an organism, but it is not known whether associations between gut bacteria and their host are heritable. Grieneisen et …
Auto-immune #hepatitis following #COVID vaccination
https://2medical.news/2021/07/14/auto-immune-hepatitis-following-covid-vaccination/
https://2medical.news/2021/07/14/auto-immune-hepatitis-following-covid-vaccination/
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Auto-immune #hepatitis following #COVID vaccination
Unprecedented loss of life due to the COVID pandemic has necessitated the development of several vaccines in record time. Most of these vaccines have received approval without being extensively whe…
Deaths in Children and #Young People in England following #SARS-CoV-2 infection during the first pandemic year: a national study using linked mandatory child death reporting data
https://2medical.news/2021/07/15/deaths-in-children-and-young-people-in-england-following-sars-cov-2-infection-during-the-first-pandemic-year-a-national-study-using-linked-mandatory-child-death-reporting-data/
https://2medical.news/2021/07/15/deaths-in-children-and-young-people-in-england-following-sars-cov-2-infection-during-the-first-pandemic-year-a-national-study-using-linked-mandatory-child-death-reporting-data/
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Deaths in Children and #Young People in England following #SARS-CoV-2 infection during the first pandemic year: a national study…
This is a preprint. It has not completed peer review. Background Deaths in children and young people (CYP) following SARS-CoV-2 infection are rare. Quantifying the risk of mortality is challenging …
#Parkinson’s Disease Motor Symptom Progression Slowed with Multisensory #Dance Learning over 3-Years: A Preliminary Longitudinal Investigation
https://2medical.news/2021/07/15/parkinsons-disease-motor-symptom-progression-slowed-with-multisensory-dance-learning-over-3-years-a-preliminary-longitudinal-investigation/
https://2medical.news/2021/07/15/parkinsons-disease-motor-symptom-progression-slowed-with-multisensory-dance-learning-over-3-years-a-preliminary-longitudinal-investigation/
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#Parkinson’s Disease Motor Symptom Progression Slowed with Multisensory #Dance Learning over 3-Years: A Preliminary Longitudinal…
Parkinson’s disease (PD) is a neurodegenerative disease that has a fast progression of motor dysfunction within the first 5 years of diagnosis, showing an annual motor rate of decline of the Moveme…
#Baricitinib reduces 30-day mortality in older adults with moderate-to-severe #COVID-19 pneumonia
https://2medical.news/2021/07/16/baricitinib-reduces-30-day-mortality-in-older-adults-with-moderate-to-severe-covid-19-pneumonia/
https://2medical.news/2021/07/16/baricitinib-reduces-30-day-mortality-in-older-adults-with-moderate-to-severe-covid-19-pneumonia/
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#Baricitinib reduces 30-day mortality in older adults with moderate-to-severe #COVID-19 pneumonia
Older adults are at the highest risk of severe disease and death due to COVID-19. Randomized data have shown that baricitinib improves outcomes in these patients, but focused stratified analyses of…
#COVID-19 #vaccine efficacy and effectiveness—the elephant (not) in the room
https://2medical.news/2021/07/16/covid-19-vaccine-efficacy-and-effectiveness-the-elephant-not-in-the-room/
https://2medical.news/2021/07/16/covid-19-vaccine-efficacy-and-effectiveness-the-elephant-not-in-the-room/
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#COVID-19 #vaccine efficacy and effectiveness—the elephant (not) in the room
Approximately 96 COVID-19 vaccines are at various stages of clinical development.1 At present, we have the interim results of four studies published in scientific journals (on the Pfizer–BioNTech B…
#Hydroxychloroquine and Mortality Among Patients With Systemic #Lupus Erythematosus in the General Population
https://2medical.news/2021/07/17/hydroxychloroquine-and-mortality-among-patients-with-systemic-lupus-erythematosus-in-the-general-population/
https://2medical.news/2021/07/17/hydroxychloroquine-and-mortality-among-patients-with-systemic-lupus-erythematosus-in-the-general-population/
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#Hydroxychloroquine and Mortality Among Patients With Systemic #Lupus Erythematosus in the General Population
Hydroxychloroquine (HCQ) has been associated with improved survival among patients with systemic lupus erythematosus (SLE) from tertiary referral centers. We aimed to determine the potential impact…