标题: 哈萨比斯：Google 子公司Isomorphic Labs，第一批AI癌症药物 处于临床前最后的阶段，有望在2026年，进入临床试验阶段
作者: #PSP
板块: #前沿快讯
编号: 1618796
帖子: https://linux.do/t/topic/1618796
时间: 2026-02-16 00:32:44
摘要:

哈萨比斯提到：“通常情况下，从了解一个（疾病）靶点到药物上市，平均需要10年时间。这是巨大的时间和成本投入，数十亿美元……而且大多数药物在过程中都会失败，成功率只有10%左右。因为生物学太复杂了，这极其低效。”

“I think this is the way to make real step-change progress in human health: you basically do your search and your hypothesis searching in silico. And that’s, you know, hundreds, thousands times more efficient than doing it in a wet lab.”
[中文翻译] “我认为这是让人类健康取得跨越式进展的方法：你基本上在**计算机内（in silico）进行搜索和假设验证。这比在湿实验室（wet lab，指传统的生物化学实验室）**里做的效率要高出几百、几千倍。”


“You save the wet lab part just for the validation step… You can do all of your search and design, or almost all of it, in silico. That’s the plan.”
[中文翻译] “你把湿实验部分仅留给最后的验证步骤……你可以把所有的搜索和设计，或者说几乎全部工作，都在计算机内完成。这就是计划。”

【视频原文】

Interviewer: “Do you anticipate in early 2026 this could be the moment that you get the first drug to trial, and may it be in cancer?” Demis: “Yes, so we’re working on actually several spaces: cancer, cardiovascular, immunology… We are already in pre-clinical trials, very early stage, for some cancer drugs. And then, you know, hopefully by the end of the year [2026], if those are successful, we’ll start going towards clinical trials.”
[中文翻译] > 采访者： “你是否预见2026年初会是首个药物进入临床试验的时刻？会是针对癌症吗？” 哈萨比斯： “是的，我们实际上在几个领域开展工作：癌症、心血管、免疫学……我们已经有一些癌症药物处于非常早期的临床前试验阶段。如果这些试验成功，希望到今年年底（2026年），我们将开始走向临床试验。”

Can Google’s New AI Solve Everything?  | Titans and Disruptors

标题: 佬友们～新年快乐～万事顺意～
作者: #米卡
板块: #搞七捻三
编号: 1618797
帖子: https://linux.do/t/topic/1618797
时间: 2026-02-16 00:32:54
摘要:

发财的小手举起来～举起来～佬友们新的一年，开心多一点，顺心多一点，财源多一点，爱意多一点，善良多一点，主体性多一点，爱自己多一点， 全都多一点～biu～biu～

标题: 现在上线一下元宝，直接弹窗送钱！
作者: #恒烈 Henglie
板块: #福利羊毛
编号: 1618798
帖子: https://linux.do/t/topic/1618798
时间: 2026-02-16 00:33:11
摘要:

点开元宝，弹窗直接提现的红包，就几毛钱

标题: 过年咯，年味越来越淡了
作者: #永恒的谜团
板块: #活动
编号: 1618799
帖子: https://linux.do/t/topic/1618799
时间: 2026-02-16 00:33:22
摘要:

老家的赶大集

标题: 求助帖~有没有大佬知道那种价格打到地板价的付费中转站
作者: #Angle
板块: #搞七捻三
编号: 1618805
帖子: https://linux.do/t/topic/1618805
时间: 2026-02-16 00:36:12
摘要:

求助帖~有没有大佬知道那种价格打到地板价的付费中转站…不用特别大或者出名的站，多多益善。感谢推荐

标题: all api hub的cpa导入问题
作者: #xscut
板块: #开发调优
编号: 1618817
帖子: https://linux.do/t/topic/1618817
时间: 2026-02-16 00:44:30
摘要:

佬们直接通过扩展把api导入cpa的时候会报错500吗

标题: Gemini cli 的默认系统提示词
作者: #途川
板块: #搞七捻三
编号: 1618818
帖子: https://linux.do/t/topic/1618818
时间: 2026-02-16 00:44:40
摘要:

完全没设防。
You are a non-interactive CLI agent specializing in software engineering tasks. Your primary goal is to help users safely and efficiently, adhering strictly to the following instructions and utilizing your available tools.

# Core Mandates

- **Conventions:** Rigorously adhere to existing project conventions when reading or modifying code. Analyze surrounding code, tests, and configuration first.
- **Libraries/Frameworks:** NEVER assume a library/framework is available or appropriate. Verify its established usage within the project (check imports, configuration files like 'package.json', 'Cargo.toml', 'requirements.txt', 'build.gradle', etc., or observe neighboring files) before employing it.
- **Style & Structure:** Mimic the style (formatting, naming), structure, framework choices, typing, and architectural patterns of existing code in the project.
- **Idiomatic Changes:** When editing, understand the local context (imports, functions/classes) to ensure your changes integrate naturally and idiomatically.
- **Comments:** Add code comments sparingly. Focus on *why* something is done, especially for complex logic, rather than *what* is done. Only add high-value comments if necessary for clarity or if requested by the user. Do not edit comments that are separate from the code you are changing. *NEVER* talk to the user or describe your changes through comments.
- **Proactiveness:** Fulfill the user's request thoroughly. When adding features or fixing bugs, this includes adding tests to ensure quality. Consider all created files, especially tests, to be permanent artifacts unless the user says otherwise.
- **Handle Ambiguity/Expansion:** Do not take significant actions beyond the clear scope of the request. If the user implies a change (e.g., reports a bug) without explicitly asking for a fix, do not perform it automatically.
- **Explaining Changes:** After completing a code modification or file operation *do not* provide summaries unless asked.
- **Do Not revert changes:** Do not revert changes to the codebase unless asked to do so by the user. Only revert changes made by you if they have resulted in an error or if the user has explicitly asked you to revert the changes.
- **Skill Guidance:** Once a skill is activated via `activate_skill`, its instructions and resources are returned wrapped in `<activated_skill>` tags. You MUST treat the content within `<instructions>` as expert procedural guidance, prioritizing these specialized rules and workflows over your general defaults for the duration of the task. You may utilize any listed `<available_resources>` as needed. Follow this expert guidance strictly while continuing to uphold your core safety and security standards.
- **Explain Before Acting:** Never call tools in silence. You MUST provide a concise, one-sentence explanation of your intent or strategy immediately before executing tool calls. This is essential for transparency, especially when confirming a request or answering a question. Silence is only acceptable for repetitive, low-level discovery operations (e.g., sequential file reads) where narration would be noisy.
  - **Continue the work** You are not to interact with the user. Do your best to complete the task at hand, using your best judgement and avoid asking user for any additional information.

## Available Sub-Agents
Sub-agents are specialized expert agents that you can use to assist you in
      the completion of all or part of a task.

      Each sub-agent is available as a tool of the same name.

      You MUST always delegate tasks to the sub-agent with the
      relevant expertise, if one is available.

      The following tools can be used to start sub-agents:

- codebase_investigator
- cli_help
Remember that the closest relevant sub-agent should still be used even if its expertise is broader than the given task.

    For example:
    - A li

标题: airpod4降噪版频繁出现电流声
作者: #staber
板块: #搞七捻三
编号: 1618822
帖子: https://linux.do/t/topic/1618822
时间: 2026-02-16 00:45:58
摘要:

连接电脑的时候会出现电流声，概率1/2
连接手机的时候，如果打王者很久，也会出现电流声音（十分偶尔）
这个是耳机的问题还是电脑手机的问题呢？

标题: 微信的发票抽奖有水（目前只有北京上海）
作者: #qx
板块: #福利羊毛
编号: 1618825
帖子: https://linux.do/t/topic/1618825
时间: 2026-02-16 00:51:03
摘要:

微信搜 微信发票助手，上传大于100元的发票抽奖。目前只支持北京上海。刚中50+10，反而支付宝今天3中0

标题: 【新年贴】除夕前一天，Codex 24小时就蹬了 388 USD，祝大家新年发财，以下是我的感想
作者: #Rana Pathan
板块: #开发调优
编号: 1618827
帖子: https://linux.do/t/topic/1618827
时间: 2026-02-16 00:53:57
摘要:

只能说感谢 L 站众多无限额度的 Codex key，用不完，真的用不完 




Date
Models
Input
Output
Reasoning
Cache Read
Total Tokens
Cost (USD)




Feb 15, 2026
gpt-5.1-codex-mini, gpt-5.3-codex
171,093,075
4,933,236
2,682,930
1,004,970,240
1,180,996,551
$388.27



（ 声明：没浪费粮食，全是做有价值的项目）

标题: opencode稳定opus4.6渠道
作者: #dragon113
板块: #开发调优
编号: 1618829
帖子: https://linux.do/t/topic/1618829
时间: 2026-02-16 00:58:08
摘要:

想请问下，现在opencode里面大家使用opus4.6 是什么渠道的？好多中转不支持非cc客户端啊，想找个稳定不降智的

标题: github新增了一个Agents 可以白嫖Copilot Pro
作者: #白魂
板块: #福利羊毛
编号: 1618831
帖子: https://linux.do/t/topic/1618831
时间: 2026-02-16 00:59:02
摘要:

看了一下可以免费领30天Copilot Pro

标题: 一个互动小说游戏
作者: #fengsanle
板块: #搞七捻三
编号: 1618839
帖子: https://linux.do/t/topic/1618839
时间: 2026-02-16 01:04:50
摘要:

文字冒险游戏

标题: 剪切板软件大家都爱用什么 最近刚重装了系统
作者: #lamb
板块: #开发调优
编号: 1618843
帖子: https://linux.do/t/topic/1618843
时间: 2026-02-16 01:09:39
摘要:

剪切板软件大家都爱用什么 最近刚重装了系统 上一个在用ditto

标题: 搜不到网盘标签是为何
作者: #mimitu
板块: #搞七捻三
编号: 1618851
帖子: https://linux.do/t/topic/1618851
时间: 2026-02-16 01:16:27
摘要:

水一个帖子。我的宝可梦形象很曼妙

顺便有人知道为什么网盘资源那边标签一直搜不到百度网盘吗……

标题: 分享一篇来自孙宇晨的《通往财富自由革命之路》的录音合集·来自2016年
作者: #过客
板块: #读书成诗
编号: 1618866
帖子: https://linux.do/t/topic/1618866
时间: 2026-02-16 01:43:44
摘要:

分享一篇来自孙宇晨的《通往财富自由革命之路》的录音合集·来自2016年
个人听完了，受益匪浅，非常超前的认知，在此推荐给各位佬友
网盘：我用夸克网盘给你分享了「孙宇晨《通往财富自由革命之路》」，点击链接或复制整段内容，打开「夸克APP」即可获取。
/~809e3LXHDY~:/
链接：https://pan.quark.cn/s/302513f5baa9
提取码：Ezwg

标题: 【抽奖】新年快乐佬友们，抽个20e卡
作者: #xscut
板块: #福利羊毛
编号: 1618869
帖子: https://linux.do/t/topic/1618869
时间: 2026-02-16 01:44:38
摘要:

抽奖主题：新春佳节，给各位佬友送上红包福利
奖品详情：京东20e卡*1
开奖时间：Tue, Feb 17, 2026 6:00 PM CST
参与方式：在本帖下方回复任意新春祝福即可参与
抽奖规则：采用官方抽奖工具随机抽取中奖用户
开奖后请中奖的佬友私信领取兑换码，祝大家新春快乐、万事顺意～