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Causes of Rhabdomyolysis:
β’ Traumatic, direct injury.
β’ Non-traumatic exertional.
β’ Non-traumatic non-exertional.
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Rhabdomyolysis
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Causes of Rhabdomyolysis:
β’ Traumatic, direct injury.
β’ Non-traumatic exertional.
β’ Non-traumatic non-exertional.
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Rhabdomyolysis
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Gout: Inflammatory monarticular arthritis, caused by the precipitation of monosodium urate crystal into tissue, usually in and around joints.
Prevalence differs regionallyβοΈ
i.e. rare in African Americans and very common in
Asians.
Gout: Inflammatory monarticular arthritis, caused by the precipitation of monosodium urate crystal into tissue, usually in and around joints.
Prevalence differs regionallyβοΈ
i.e. rare in African Americans and very common in
Asians.
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Arthrocentesis is a definitive diagnosis test for GoutβοΈ
Gout vs. Psueodogout:
β’ Hallmark of gout needle-shaped crystals with negative birefringent crystals.
β’ Pseudogout has rhomboid shaped needles and slightly positive birefringence.
Arthrocentesis is a definitive diagnosis test for GoutβοΈ
Gout vs. Psueodogout:
β’ Hallmark of gout needle-shaped crystals with negative birefringent crystals.
β’ Pseudogout has rhomboid shaped needles and slightly positive birefringence.
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Osteoarthritis is a degenerative joint disease that results from breakdown of joint cartilage and underlying bone.
β’ The most common form of arthritis, often affects joints of the hands, knees, hips and spine.
β’ The pain and stiffness may become severe enough to affect daily activities.
Osteoarthritis is a degenerative joint disease that results from breakdown of joint cartilage and underlying bone.
β’ The most common form of arthritis, often affects joints of the hands, knees, hips and spine.
β’ The pain and stiffness may become severe enough to affect daily activities.
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Hashimoto's Thyroiditis: A condition in which altered T-cell-mediated immunity causes destruction of thyroid tissue and impaired gland function.
β’ Also called: Chronic Lymphatic Thyroiditis.
β’ The condition is characterized by a lymphocytic infiltrate and fibrosis.
Hashimoto's Thyroiditis: A condition in which altered T-cell-mediated immunity causes destruction of thyroid tissue and impaired gland function.
β’ Also called: Chronic Lymphatic Thyroiditis.
β’ The condition is characterized by a lymphocytic infiltrate and fibrosis.
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Hyperthyroidism: An increase in the circulating thyroid hormones (T3 & T4) due to an increase in its synthesis with a decrease in TSH levels.
Types:
β’ Primary, caused by conditions related to the thyroid gland.
β’ Secondary, caused by extra-thyroidal conditions like pituitary gland.
Hyperthyroidism: An increase in the circulating thyroid hormones (T3 & T4) due to an increase in its synthesis with a decrease in TSH levels.
Types:
β’ Primary, caused by conditions related to the thyroid gland.
β’ Secondary, caused by extra-thyroidal conditions like pituitary gland.
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GIT functional motility:
β’ Peristaltic or propulsive.
β’ Segmentation or mixing.
β’ Storage.
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GIT Physiology
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GIT functional motility:
β’ Peristaltic or propulsive.
β’ Segmentation or mixing.
β’ Storage.
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GIT Physiology
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Appendicitis: Inflammation of the appendix.
Epidemiology:
β’ It is the most common cause of acute abdomen requiring surgery.
β’ The peak incidence for appendicitis is 10-30 years old.
β’ Mortality rate is 0.1% in non-perforated cases.
Appendicitis: Inflammation of the appendix.
Epidemiology:
β’ It is the most common cause of acute abdomen requiring surgery.
β’ The peak incidence for appendicitis is 10-30 years old.
β’ Mortality rate is 0.1% in non-perforated cases.
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Obturator sign:
Passive internal rotation of the thigh will elicit pain in the RLQ.
Usually seen in pelvic appendicitisβοΈ
Obturator sign:
Passive internal rotation of the thigh will elicit pain in the RLQ.
Usually seen in pelvic appendicitisβοΈ
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Paralytic ileus/Adynamic bowel: Failure to move the luminal contents due to poor motility.
Simple bowel obstruction: Blockage of the bowel lumen at one area without complications (perforation, strangulation etc.).
Paralytic ileus/Adynamic bowel: Failure to move the luminal contents due to poor motility.
Simple bowel obstruction: Blockage of the bowel lumen at one area without complications (perforation, strangulation etc.).
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Causes of peptic ulcer disease:
β’ Smoking.
β’ NSAIDs.
β’ H. pylori.
β’ Other.
Causes of peptic ulcer disease:
β’ Smoking.
β’ NSAIDs.
β’ H. pylori.
β’ Other.
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Nephritic syndrome is a manifestation of glomerular inflammation, glomerulonephritis [GN], due to many causes leading to leakage of the larger cells (red blood cells β plasma proteins) through the filtration barrier.
Nephritic syndrome is a manifestation of glomerular inflammation, glomerulonephritis [GN], due to many causes leading to leakage of the larger cells (red blood cells β plasma proteins) through the filtration barrier.
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Classic features of nephritic syndrome:
β’ Hematuria.
β’ Edema.
β’ Hypertension.
Classic features of nephritic syndrome:
β’ Hematuria.
β’ Edema.
β’ Hypertension.
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P-THORAX summaries the presentation of pneumothorax:
Pleuritic chest pain.
Tracheal deviation.
Hyper-resonance on percussion.
Onset is sudden.
Reduced breath sounds unilaterally.
Absent fremitus.
X-ray shows lung collapse.
P-THORAX summaries the presentation of pneumothorax:
Pleuritic chest pain.
Tracheal deviation.
Hyper-resonance on percussion.
Onset is sudden.
Reduced breath sounds unilaterally.
Absent fremitus.
X-ray shows lung collapse.
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Pulmonary Embolism: It is basically a blood clot that forms in the venous system traveling to the lung causing obstruction of the pulmonary vasculature.
β’ It is suggested by the presence of acute onset of dyspnea, pleuritic chest pain, hypoxia, hemoptysis, low-grade fever, and tachycardia.
Pulmonary Embolism: It is basically a blood clot that forms in the venous system traveling to the lung causing obstruction of the pulmonary vasculature.
β’ It is suggested by the presence of acute onset of dyspnea, pleuritic chest pain, hypoxia, hemoptysis, low-grade fever, and tachycardia.
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Consider thrombolytic therapy as a treatment for a PE patient only if the patient is hemodynamically unstable (low SBP<90mmHg), and in cases of acute right ventricular dysfunction.
Consider thrombolytic therapy as a treatment for a PE patient only if the patient is hemodynamically unstable (low SBP<90mmHg), and in cases of acute right ventricular dysfunction.
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Sources of [H+]:
β’ Carbonic acid formation: the major source of H+ is from metabolically produced CO2.
β’ Inorganic acid produced during nutrient breakdown: dietary proteins contain a large quantity of sulfuric acid and phosphoric acid.
β’ Organic acid resulting from intermediary metabolism: lactic acid and fatty acids.
Sources of [H+]:
β’ Carbonic acid formation: the major source of H+ is from metabolically produced CO2.
β’ Inorganic acid produced during nutrient breakdown: dietary proteins contain a large quantity of sulfuric acid and phosphoric acid.
β’ Organic acid resulting from intermediary metabolism: lactic acid and fatty acids.
PPD test for Tuberculosis:
β’ β₯5mm induration in high risk group β‘οΈHIV, and close contact.
β’ β₯10mm induration in moderate risk group β‘οΈmedical comorbidities, healthcare workers, and immigrants within the past 5 years.
β’ β₯15mm induration in low risk group β‘οΈnormal healthy individuals.
β’ β₯5mm induration in high risk group β‘οΈHIV, and close contact.
β’ β₯10mm induration in moderate risk group β‘οΈmedical comorbidities, healthcare workers, and immigrants within the past 5 years.
β’ β₯15mm induration in low risk group β‘οΈnormal healthy individuals.