Let's Talk Medicine
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Let's Talk Medicine pinned «Dear followers, Our posts are temporarily stopping for the next few days. Posts will resume after Eid Al-Fitr on June 19th. May Allah bless you all during these last few days of Ramadan.✨»
Happy Eid everyone!
We hope you have a wonderful time with your family and friends.🎈
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Dyslipidemia: A broad term describing disorders of lipoprotein metabolism, including overproduction or deficiency.
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Hyperlipidemia: A condition characterized by ↑ serum levels of total cholesterol, low-density lipoprotein cholesterol (LDL), or non-high-density lipoprotein cholesterol (HDL).
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Clinical Presentation of Hyperlipidemia:
Mostly asymptomatic.
In severe hyperlipidemia may present with:
β€’ Xanthelasma, yellow plaques on eyelid.
β€’ Xanthoma, irregular yellow nodule found on tendons.
β€’ Pancreatitis [hypertriglyceridemia].
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Rhabdomyolysis:
β€’ Syndrome characterized by muscle necrosis and the release of intracellular muscle constituents into the circulation.
β€’ Elevated CK, muscle pain, and myoglobinuria.
β€’ Presentation has a wide range of variety.
Let's Talk Medicine pinned Β«πŸ”΄ Rhabdomyolysis: β€’ Syndrome characterized by muscle necrosis and the release of intracellular muscle constituents into the circulation. β€’ Elevated CK, muscle pain, and myoglobinuria. β€’ Presentation has a wide range of variety.Β»
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Causes of Rhabdomyolysis:
β€’ Traumatic, direct injury.
β€’ Non-traumatic exertional.
β€’ Non-traumatic non-exertional.

Check this out for more!
Rhabdomyolysis
πŸ”—: http://bit.ly/2rR0Cyo
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Gout: Inflammatory monarticular arthritis, caused by the precipitation of monosodium urate crystal into tissue, usually in and around joints.

Prevalence differs regionally❗️
i.e. rare in African Americans and very common in
Asians.
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Arthrocentesis is a definitive diagnosis test for Gout❗️

Gout vs. Psueodogout:
β€’ Hallmark of gout needle-shaped crystals with negative birefringent crystals.
β€’ Pseudogout has rhomboid shaped needles and slightly positive birefringence.
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Osteoarthritis is a degenerative joint disease that results from breakdown of joint cartilage and underlying bone.

β€’ The most common form of arthritis, often affects joints of the hands, knees, hips and spine.
β€’ The pain and stiffness may become severe enough to affect daily activities.
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Hashimoto's Thyroiditis: A condition in which altered T-cell-mediated immunity causes destruction of thyroid tissue and impaired gland function.

β€’ Also called: Chronic Lymphatic Thyroiditis.
β€’ The condition is characterized by a lymphocytic infiltrate and fibrosis.
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Hyperthyroidism: An increase in the circulating thyroid hormones (T3 & T4) due to an increase in its synthesis with a decrease in TSH levels.

Types:
β€’ Primary, caused by conditions related to the thyroid gland.
β€’ Secondary, caused by extra-thyroidal conditions like pituitary gland.
πŸ”΄ Thyroid hormones key points
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GIT functional motility:
β€’ Peristaltic or propulsive.
β€’ Segmentation or mixing.
β€’ Storage.

Check this out for more!
GIT Physiology
πŸ“Ή: http://bit.ly/2ofnBBe
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Appendicitis: Inflammation of the appendix.

Epidemiology:
β€’ It is the most common cause of acute abdomen requiring surgery.
β€’ The peak incidence for appendicitis is 10-30 years old.
β€’ Mortality rate is 0.1% in non-perforated cases.
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Obturator sign:
Passive internal rotation of the thigh will elicit pain in the RLQ.

Usually seen in pelvic appendicitis❗️
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Paralytic ileus/Adynamic bowel: Failure to move the luminal contents due to poor motility.

Simple bowel obstruction: Blockage of the bowel lumen at one area without complications (perforation, strangulation etc.).
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Causes of peptic ulcer disease:
β€’ Smoking.
β€’ NSAIDs.
β€’ H. pylori.
β€’ Other.
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Nephritic syndrome is a manifestation of glomerular inflammation, glomerulonephritis [GN], due to many causes leading to leakage of the larger cells (red blood cells – plasma proteins) through the filtration barrier.