Let's Talk Medicine
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Endocrine changes during pregnancy:

⬆️Insulin production & response:
• Blood sugar level usually remains normal, or sometimes becomes low.
•Sometimes the insulin response is met with resistance caused predominantly by human placental lactogen.

⬇️Follicular stimulating & luteinising hormones.

⬆️ACTH & melanocyte-stimulating hormone.

⬆️Prolactin.
Dear followers,
Our posts are temporarily stopping for the next few days. Posts will resume after Eid Al-Fitr on June 19th.

May Allah bless you all during these last few days of Ramadan.✨
Let's Talk Medicine pinned «Dear followers, Our posts are temporarily stopping for the next few days. Posts will resume after Eid Al-Fitr on June 19th. May Allah bless you all during these last few days of Ramadan.✨»
Happy Eid everyone!
We hope you have a wonderful time with your family and friends.🎈
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Dyslipidemia: A broad term describing disorders of lipoprotein metabolism, including overproduction or deficiency.
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Hyperlipidemia: A condition characterized by ↑ serum levels of total cholesterol, low-density lipoprotein cholesterol (LDL), or non-high-density lipoprotein cholesterol (HDL).
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Clinical Presentation of Hyperlipidemia:
Mostly asymptomatic.
In severe hyperlipidemia may present with:
• Xanthelasma, yellow plaques on eyelid.
• Xanthoma, irregular yellow nodule found on tendons.
• Pancreatitis [hypertriglyceridemia].
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Rhabdomyolysis:
• Syndrome characterized by muscle necrosis and the release of intracellular muscle constituents into the circulation.
• Elevated CK, muscle pain, and myoglobinuria.
• Presentation has a wide range of variety.
Let's Talk Medicine pinned «🔴 Rhabdomyolysis: • Syndrome characterized by muscle necrosis and the release of intracellular muscle constituents into the circulation. • Elevated CK, muscle pain, and myoglobinuria. • Presentation has a wide range of variety.»
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Causes of Rhabdomyolysis:
• Traumatic, direct injury.
• Non-traumatic exertional.
• Non-traumatic non-exertional.

Check this out for more!
Rhabdomyolysis
🔗: http://bit.ly/2rR0Cyo
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Gout: Inflammatory monarticular arthritis, caused by the precipitation of monosodium urate crystal into tissue, usually in and around joints.

Prevalence differs regionally❗️
i.e. rare in African Americans and very common in
Asians.
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Arthrocentesis is a definitive diagnosis test for Gout❗️

Gout vs. Psueodogout:
• Hallmark of gout needle-shaped crystals with negative birefringent crystals.
• Pseudogout has rhomboid shaped needles and slightly positive birefringence.
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Osteoarthritis is a degenerative joint disease that results from breakdown of joint cartilage and underlying bone.

• The most common form of arthritis, often affects joints of the hands, knees, hips and spine.
• The pain and stiffness may become severe enough to affect daily activities.
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Hashimoto's Thyroiditis: A condition in which altered T-cell-mediated immunity causes destruction of thyroid tissue and impaired gland function.

• Also called: Chronic Lymphatic Thyroiditis.
• The condition is characterized by a lymphocytic infiltrate and fibrosis.
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Hyperthyroidism: An increase in the circulating thyroid hormones (T3 & T4) due to an increase in its synthesis with a decrease in TSH levels.

Types:
• Primary, caused by conditions related to the thyroid gland.
• Secondary, caused by extra-thyroidal conditions like pituitary gland.
🔴 Thyroid hormones key points
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GIT functional motility:
• Peristaltic or propulsive.
• Segmentation or mixing.
• Storage.

Check this out for more!
GIT Physiology
📹: http://bit.ly/2ofnBBe
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Appendicitis: Inflammation of the appendix.

Epidemiology:
• It is the most common cause of acute abdomen requiring surgery.
• The peak incidence for appendicitis is 10-30 years old.
• Mortality rate is 0.1% in non-perforated cases.
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Obturator sign:
Passive internal rotation of the thigh will elicit pain in the RLQ.

Usually seen in pelvic appendicitis❗️
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Paralytic ileus/Adynamic bowel: Failure to move the luminal contents due to poor motility.

Simple bowel obstruction: Blockage of the bowel lumen at one area without complications (perforation, strangulation etc.).