MCQ NO 787 | Pharmacology
Auto rhythmicity is present in which of the following group of tissues ?
Auto rhythmicity is present in which of the following group of tissues ?
Anonymous Quiz
15%
(a) Skeletal muscle and cardiac muscle
22%
(b) Skeletal muscle and visceral smooth muscle
23%
(c) Cardiac muscle and neuronal tissue
40%
(d) Cardiac muscle and visceral smooth muscle
MCQ NO 788 | pharmaceutical biotechnology
During the denaturation cycle in polymerase chain reaction the temperature is raised to:
During the denaturation cycle in polymerase chain reaction the temperature is raised to:
Anonymous Quiz
58%
(a) 90 -98°C
17%
(b) 60 - 68°C
22%
(c) 70 - 78°C
3%
(d) 80 - 88°C
MCQ NO 789 | Pharmacology
Which one of the following is not a renal osteodystrophy (type of bone disease associated with chronic kidney disease) ?
Which one of the following is not a renal osteodystrophy (type of bone disease associated with chronic kidney disease) ?
Anonymous Quiz
15%
(a) Adynamic bone disease
31%
(b) Osteomalacia
45%
(c) Secondary hypoparathyroidism
9%
(d) Mixed renal osteodystrophy
MCQ NO 790 | Pharmacology
Identify antiarrhythmic drug that increases duration of QT wave and decreases the sinus rate, whereas it has no effect on QRS complex
Identify antiarrhythmic drug that increases duration of QT wave and decreases the sinus rate, whereas it has no effect on QRS complex
Anonymous Quiz
21%
(a) Lidocaine
34%
(b) Amiodarone
27%
(c) Verapamil
17%
(d) Quinidine
🔴DEFINITION
5-HT3 antagonist:
The 5-HT3 antagonists, informally known as "setrons", are a class of drugs that act as receptor antagonists at the 5-HT3 receptor, a subtype of serotonin receptor found in terminals of the vagus nerve and in certain areas of the brain.
🔶Antagonist:
A substance that acts against and blocks an action.
🔶Agonist:
A substance that acts like another substance and therefore stimulates an action.
🔶Glidants:
The substance which is used to promote flow of tablets/powders by reducing friction between particles.
🔶Anti-adherents:
Which reduces sticking of any tablets to faces of punches.
5-HT3 antagonist:
The 5-HT3 antagonists, informally known as "setrons", are a class of drugs that act as receptor antagonists at the 5-HT3 receptor, a subtype of serotonin receptor found in terminals of the vagus nerve and in certain areas of the brain.
🔶Antagonist:
A substance that acts against and blocks an action.
🔶Agonist:
A substance that acts like another substance and therefore stimulates an action.
🔶Glidants:
The substance which is used to promote flow of tablets/powders by reducing friction between particles.
🔶Anti-adherents:
Which reduces sticking of any tablets to faces of punches.
🔴MECHANIAM OF ACTION🔴
📌 5HT3 ANTAGONISTS
Selective serotonin receptor (5-HT3) antagonists block serotonin both peripherally on vagal nerve terminals in the gastrointestinal (GI) system and centrally in the chemoreceptor trigger zone in the area postrema of the fourth ventricle, resulting in powerful antiemetic effects.
📌 5HT3 ANTAGONISTS
Selective serotonin receptor (5-HT3) antagonists block serotonin both peripherally on vagal nerve terminals in the gastrointestinal (GI) system and centrally in the chemoreceptor trigger zone in the area postrema of the fourth ventricle, resulting in powerful antiemetic effects.
🔴DEFINITION
🔶Certified colours :
The colours which are approved by FDC act to used in tablets is called as certified colours.
🔶 Bioavailability :
Amount of percentage of active drug that is being absorbed from the given dosage form and made available to the site of action.
🔶 Drug idiosyncrasy:
Unwanted abnormal reaction to the drug different from the expected reaction generally due to genetic deficiency.
🔶Certified colours :
The colours which are approved by FDC act to used in tablets is called as certified colours.
🔶 Bioavailability :
Amount of percentage of active drug that is being absorbed from the given dosage form and made available to the site of action.
🔶 Drug idiosyncrasy:
Unwanted abnormal reaction to the drug different from the expected reaction generally due to genetic deficiency.
🔴 MECHANISM OF ACTION🔴
📌 METOCLOPRAMIDE
◾Metoclopramide works by antagonizing central and peripheral dopamine two receptors in the medullary chemoreceptor trigger zone in the area postrema that are normally stimulated by levodopa or apomorphine.
◾ It achieves this by decreasing the sensitivity of visceral afferent nerves that transmit from the gastrointestinal system to the vomiting center in the area postrema in the chemoreceptor trigger zone.
📌ERGOTAMINE
◾It acts as a partial agonist and antagonist at alfa adrenergic and all subtype of 5HT1 anf 5HT2 receptor
◾It is a potent emetic and moderately potent oxytocic
📌 METOCLOPRAMIDE
◾Metoclopramide works by antagonizing central and peripheral dopamine two receptors in the medullary chemoreceptor trigger zone in the area postrema that are normally stimulated by levodopa or apomorphine.
◾ It achieves this by decreasing the sensitivity of visceral afferent nerves that transmit from the gastrointestinal system to the vomiting center in the area postrema in the chemoreceptor trigger zone.
📌ERGOTAMINE
◾It acts as a partial agonist and antagonist at alfa adrenergic and all subtype of 5HT1 anf 5HT2 receptor
◾It is a potent emetic and moderately potent oxytocic
🔴ADR OF SIMPLE ANALGESICS🔴
➡️Nausea
➡️Dyspepsia
🔴ADR OF NSAIDS🔴
➡️Ulcers
➡️Bleeding
➡️Kidney failure
➡️Rarely liver failure
🔴ADR OF ANTIEMETICS🔴
➡️Drowsiness
➡️Dry mouth
➡️Fatigue
➡️Constipation
➡️Tinnitus
➡️Muscle spasms
🔴ADR OF ERGOT ALKALOIDS🔴
➡️Nausea
➡️Vomiting
➡️Muscle pain
➡️Itching
➡️Numbness
➡️Rapid or slow heartbeat
➡️Nausea
➡️Dyspepsia
🔴ADR OF NSAIDS🔴
➡️Ulcers
➡️Bleeding
➡️Kidney failure
➡️Rarely liver failure
🔴ADR OF ANTIEMETICS🔴
➡️Drowsiness
➡️Dry mouth
➡️Fatigue
➡️Constipation
➡️Tinnitus
➡️Muscle spasms
🔴ADR OF ERGOT ALKALOIDS🔴
➡️Nausea
➡️Vomiting
➡️Muscle pain
➡️Itching
➡️Numbness
➡️Rapid or slow heartbeat
MCQ NO. 791 | Pharmacology
Insulin injection comes under the schedule
Insulin injection comes under the schedule
Anonymous Quiz
30%
A. G
49%
B. C
14%
C. P
7%
D. W
MCQ NO . 792 | pharmaceutical jurisprudence
For registration of pharmacist in the various states, the pharmacy act provides for the constitution of
For registration of pharmacist in the various states, the pharmacy act provides for the constitution of
Anonymous Quiz
38%
A. Central pharmacy Council
14%
B. Registration Tribunals
5%
C. Corporative Societies
43%
D. State Pharmacy Council
MCQ NO 793 | pharmaceutical jurisprudence
The drugs &cosmetic act & rule were passed?
The drugs &cosmetic act & rule were passed?
Anonymous Quiz
15%
A. 1940 & 1942
61%
B. 1940 &1945
21%
C. 1945 &1948
3%
D. 1945 & 1947
MCQ NO . 794 | Pharmacology
Which immunoglobulin is agglutinating and cytolytic
Which immunoglobulin is agglutinating and cytolytic
Anonymous Quiz
30%
A. IgG
35%
B. IgM
18%
C .IgA
17%
D . IgE
MCQ NO . 795 | Microbiology
Microorganism having the comma and S shaped form
Microorganism having the comma and S shaped form
Anonymous Quiz
30%
A. Streptococci
9%
B. Sarcina
6%
C. B.antracis
55%
D. Vibrio and Spirilla
MCQ NO 796 | Pharmacology
Among the immunising agents listed below one of them is orally administered. Identify.
Among the immunising agents listed below one of them is orally administered. Identify.
Anonymous Quiz
14%
A. Taranus toxid
13%
B. Rabies vaccine
62%
C. Poliomyelitis vaccine
10%
D. Mumps virus vaccine
MCQ NO 797 | pharmaceutical jurisprudence
List of coaltar colours permitted to be used in cosmetics is come under schedule
List of coaltar colours permitted to be used in cosmetics is come under schedule
Anonymous Quiz
12%
A. O
14%
B. P
68%
C. Q
7%
D. R
MCQ NO 798 | pharmaceutical jurisprudence
Drug Inspector is appointed under section-----of the act.
Drug Inspector is appointed under section-----of the act.
Anonymous Quiz
11%
A. 42 of IPC
70%
B. 21 of IPC
13%
C. 46 of IPC
6%
D. 31 of IPC
MCQ NO 799 | Microbiology
Which of the following microorganism is particularly dangerous to the eyes
Which of the following microorganism is particularly dangerous to the eyes
Anonymous Quiz
15%
A. E. Coli
22%
B. S. Thermophilus
49%
C. P. Aeruginosa
14%
D. S. Cerevisiae
MCQ NO 800 | Microbiology
Chemotaxis is a phenomenon that refers to:
Chemotaxis is a phenomenon that refers to:
Anonymous Quiz
45%
A) directed movement in response to a chemical stimulus
25%
B) taxonomic classification of biochemicals
24%
C) large influx of a chemical molecule within bacterial cells
6%
D) adherence of bacterial proteins to host cells