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Mcq no 183

Precursor for biosynthesis of tropane alkaloids is
Anonymous Quiz
10%
A.Leucine
15%
B.Lysine
54%
C.Ornithine
22%
D.Tyrosine
Mcq no 184

The sugar moeity of Digitalis purpurea is
Anonymous Quiz
8%
A. 2,6deoxyallose
46%
B. 2,6 deoxyrhamnose
32%
C. 2,6 deoxyglucose
14%
D. 2,6 deoxygalactose
Mcq no 185

Powdered digitalis is dried at temperature..
Anonymous Quiz
52%
A. Not exceeding 60°c
27%
B. 65°c
18%
C. 75°c
2%
D. 100°c
Mcq no 187

Biuret test is used to detect
Anonymous Quiz
28%
A. Carbohydrates
13%
B.lipids
54%
C. Proteins
5%
D. Nucleic acid
Mcq no 188

One of the following is confirmed by DNA diagnosis test
Anonymous Quiz
12%
A. Hyperuricemia
52%
B.Cystic fibrosis
24%
C.Acute pancreatitis
12%
D. Hyperuricemia
Mcq no189

Polyneuritis is a disease of which vitamin deficiency
Anonymous Quiz
19%
A. Thiamine
31%
B.Ascorbic acid
34%
C. Pyridoxine
16%
D.Nicotinamide
MCQ. No.191| General Pharmacology

FDA assigns the letters A, B, C, D, and X to drugs approved for human use. To which of the following does this classification apply?
Anonymous Quiz
22%
Fetal risk when given to pregnant women
22%
The number of unlabeled uses for a drug
38%
Relative margins of safety/therapeutic index
17%
Amount of dosage reduction needed in presence of liver dysfunction
MCQ. No.192| General pharmacology

Dopamine, epinephrine and histamine are important neurotransmitter agonists. When these ligands interact with their cellular receptors, how do they mainly elicit their responses?
Anonymous Quiz
19%
Opening or closing ligand-gated ion channels
11%
Activating phospholipase C
25%
Inducing or inhibiting synthesis of ligand-specific intracellular proteins
45%
Regulating intracellular second messengers through G protein-coupled receptors
MCQ. No.193| General pharmacology

Elimination of a drug is described as being heavily dependent on Phase II metabolic reactions. Which of the following is a Phase II reaction as far as drug elimination goes?
Anonymous Quiz
13%
Deamination
72%
Glucuronidation
10%
Nitro reduction
5%
Ester hydrolysis
MCQ. No.194| G.P

Experimental evaluation of pharmacokinetics of drug under development leads to finding that it “undergoes significant first-pass hepatic metabolism.” Which of the following route was most likely used to reach this conclusion?
Anonymous Quiz
15%
Sublingual
61%
Oral
19%
Intramuscular
5%
Rectal
MCQ. No.195| General pharmacology

Tolerance as well as drug resistance can be a consequence of:
Anonymous Quiz
24%
Activation of a drug after hepatic first-pass
48%
Drug dependence
13%
Depressed renal drug excretion
14%
Increased metabolic degradation
MCQ. No.196| General pharmacology

Ionizable group is responsible for which of the following:
Anonymous Quiz
20%
The ability to diffuse to the site of action
15%
The potency and the toxicity
10%
The duration of action
55%
All of the above
MCQ. No.198| General pharmacology

What phenomenon can occur in case of using a combination of drugs?
Anonymous Quiz
11%
Tachyphylaxis
73%
Synergism
12%
Tolerance
4%
Accumulation
MCQ. No.199| General pharmacology

What term is used to describe a decrease in responsiveness to a drug which develops in a few minutes?
Anonymous Quiz
12%
Refractoriness
32%
Cumulative effect
36%
Tachyphylaxis
20%
Tolerance
MCQ. No.201

Dextran40 is ____________% solution in Dextrose or Saline.
Anonymous Quiz
24%
10
28%
20
15%
30
32%
40
MCQ. No.202 to 206 involve the following case:


XYZ is a 39-year-old female with bacterial endocarditis. She is started on gentamicin 80 mg iv twice daily and penicillin G iv 1.8 g every 6 h.