MCQ NO 1349 Pharmacology
What effect does histamine have on the release of gastric acid?
What effect does histamine have on the release of gastric acid?
Anonymous Quiz
58%
a) It increases secretion
27%
b) It decreases secretion
8%
c) It has no effect
7%
d) It completely switches off secretion
MCQ NO 1350 |Pharmacology
Which of histamine H1 antagonists is noted for the serotonin-blocking effect?
Which of histamine H1 antagonists is noted for the serotonin-blocking effect?
Anonymous Quiz
28%
a) Brompheniramine
60%
b) Cyproheptadine
11%
c) Suprastine
2%
d) Dimedro
🔴 Mechanism of action 🔴
🔺 Directly acting skeletal muscle relaxants :-
🔸Examples.....
🔹1) Dantrolene :- Neuromuscular transmission or MAP are not affected.
Dantrolene acts on Ryanodine receptor present in sarcopladmic reticulum and prevents release of calcium and muscle get relaxed.
🔹2) Quinine :- It increase the refractory period and decrease the excitability of motor end plates. Thus, response to repetitive nerve stimulation are reduced.
🔺 Directly acting skeletal muscle relaxants :-
🔸Examples.....
🔹1) Dantrolene :- Neuromuscular transmission or MAP are not affected.
Dantrolene acts on Ryanodine receptor present in sarcopladmic reticulum and prevents release of calcium and muscle get relaxed.
🔹2) Quinine :- It increase the refractory period and decrease the excitability of motor end plates. Thus, response to repetitive nerve stimulation are reduced.
🔴 Mechanism of Action 🔴
🔺 Centrally acting skeletal muscle relaxants :-
🔹These drugs reduce skeletal muscle tone and lessen muscle spasm by a selective action in the cerebrospinal axis, without altering consciousness.
🔹They selectively depress spinal and supraspinal polysynaptic reflexes involved in the regulation of muscle tone without significantly affecting monosynaptically mediated stretch reflex.
🔺 Centrally acting skeletal muscle relaxants :-
🔹These drugs reduce skeletal muscle tone and lessen muscle spasm by a selective action in the cerebrospinal axis, without altering consciousness.
🔹They selectively depress spinal and supraspinal polysynaptic reflexes involved in the regulation of muscle tone without significantly affecting monosynaptically mediated stretch reflex.
MCQ NO 1351 | Pharmacology
`Essential drugs’ are:
`Essential drugs’ are:
Anonymous Quiz
17%
A. Life saving drugs
61%
B. Drugs that meet the priority health care needs of the population
15%
C. Drugs that must be present in the emergency bag of a doctor
7%
D. Drugs that are listed in the pharmacopoia of a country
MCQ NO 1352 | Pharmacology
An 'orphan drug' is:
An 'orphan drug' is:
Anonymous Quiz
5%
A. A very cheap drug
10%
B. A drug which has no therapeutic use
79%
C. A drug needed for treatment or prevention of a rare disease
6%
D. A drug which acts on Orphanin receptors
MCQ NO 1353 | Pharmacology
Drug administered through the following route is most likely to be subjected to first-pass metabolism:
Drug administered through the following route is most likely to be subjected to first-pass metabolism:
Anonymous Quiz
77%
A. Oral
12%
B. Sublingual
8%
C. Subcutaneous
2%
D. Rectal
MCQ NO 1354 | Pharmacology
Majority of drugs cross biological membranes primarily by:
Majority of drugs cross biological membranes primarily by:
Anonymous Poll
68%
A. Passive diffusion
15%
B. Facilitated diffusion
14%
C. Active transport
3%
D. Pinocytosis
MCQ NO 1355 | Pharmacology
Alkalinization of urine hastens the excretion of:
Alkalinization of urine hastens the excretion of:
Anonymous Quiz
27%
A. Weakly basic drugs
60%
B. Weakly acidic drugs
11%
C. Strong electrolytes
2%
D. Nonpolar drugs
MCQ NO 1356 | pharmaceutical jurisprudence
Central drug laboratory is located at
Central drug laboratory is located at
Anonymous Quiz
14%
A. Mumbai
35%
B. Lacknow
48%
C. Calcutta
3%
D. Hyderabad
MCQ NO 1357 | Pharmaceutical jurisprudence
PCI is reconstituted every
PCI is reconstituted every
Anonymous Quiz
16%
A. 3 years
76%
B. 5 years
5%
C. 2 years
3%
D. 6 years
MCQ NO 1358 | Pharmaceutical jurisprudence
Minimum training required to be pharmacist
Minimum training required to be pharmacist
Anonymous Quiz
14%
a) 100 hours
46%
b) 500 hours
26%
c) 300 hours
14%
d) 800 hours
MCQ NO 1359 | Pharmaceutical jurisprudence
The particular to be shown in manufacturing raw materials and analytical records of drug are dealt under……
The particular to be shown in manufacturing raw materials and analytical records of drug are dealt under……
Anonymous Quiz
30%
a) Schedule M
46%
b) Schedule U
18%
c) Schedule U1
6%
d) Schedule W
MCQ NO 1360| Pharmaceutical jurisprudence
Application to manufacture cosmetics is made to the licensing authority in….
Application to manufacture cosmetics is made to the licensing authority in….
Anonymous Quiz
17%
a) Form 31
55%
b) Form 31A
17%
c) Form 32
11%
d) Form 32A
MCQ NO 1361 | GATE 2002
The phenomenon of increasing the solubility of weak electrolytes and non polar molecules by the addition of water miscible solvent in which the drug has good solubility is called
The phenomenon of increasing the solubility of weak electrolytes and non polar molecules by the addition of water miscible solvent in which the drug has good solubility is called
Anonymous Quiz
10%
(a) Complexation
55%
(b) Cosolvancy
30%
(c) Solubilization
5%
(d) Hydrotrophy
MCQ NO 1362 | GATE 2002
HLB system is used to classify
HLB system is used to classify
Anonymous Quiz
81%
(a) Surfactants
10%
(b) Preservatives
5%
(c) Antioxidants
4%
(d) Sequestering agents
MCQ NO 1663 | GATE 2002
The statement “Store in a cool place” as per IP, means
The statement “Store in a cool place” as per IP, means
Anonymous Quiz
11%
(a) Store at room temperature
40%
(b) Store between 2° to 8° C
47%
(c) Store at any temperature between 8° to 25° C
2%
(d) Store at 0° C
MCQ NO 1664 | GATE 2002
Durability of a tablet to combined effects of shock and abrasion is evaluated by using
Durability of a tablet to combined effects of shock and abrasion is evaluated by using
Anonymous Quiz
18%
(a) Hardness tester
26%
(b) Disintegration test apparatus
52%
(c) Friabilator
4%
(d) Screw Gauge
MCQ NO 1665 | GATE 2002
Ion exchange capacity of a resin is dependent on
Ion exchange capacity of a resin is dependent on
Anonymous Quiz
25%
(a) The total molecular weight of the resin
44%
(b) The total number of ion active groups
10%
(c) Length of ion exchange resin
20%
(d) Solubility of the ion exchange resins
MCQ NO 1366 | Pharmacology
Which of the following glucocorticoids is a short- to medium-acting drug?
Which of the following glucocorticoids is a short- to medium-acting drug?
Anonymous Quiz
16%
Triamcinolone
20%
Dexamethasone
31%
Prednisolon
33%
All of the above