MCQ NO 1206 | Pharmacology
The primary mechanism of action of local anesthetics is:
The primary mechanism of action of local anesthetics is:
Anonymous Quiz
25%
Blockade the GABA-gated chloride channels
51%
Blockade of voltage-gated sodium channels
18%
Stimulation of voltage-gated N-type calcium channels
6%
Activation of ligand-gated potassium channels
MCQ NO 1207 | Pharmacology
Correct statements concerning bupivacaine include all of the following EXCEPT:
Correct statements concerning bupivacaine include all of the following EXCEPT:
Anonymous Quiz
13%
It has amide linkage
21%
It is a long-acting drug
38%
It has low cardiotoxicity
28%
An intravenous injection can lead to seizures
MCQ NO 1208 | Pharmacology
Which one of the following local anesthetics causes methemoglobinemia?
Which one of the following local anesthetics causes methemoglobinemia?
Anonymous Quiz
28%
Lidocaine
30%
Procaine
25%
Ropivacaine
17%
Prilocaine
MCQ NO 1209 | Pharmacology
Which of the following local anesthetics is more cardiotoxic?
Which of the following local anesthetics is more cardiotoxic?
Anonymous Quiz
14%
Mepivacaine
16%
Procaine
52%
Bupivacaine
18%
Lidocaine
MCQ NO 1210 | Pharmacology
Procaine has all of the following properties EXCEPT:
Procaine has all of the following properties EXCEPT:
Anonymous Quiz
10%
It has ester linkage
46%
Its metabolic product can inhibit the action of sulfonamides
22%
It is relatively short-acting
22%
It readily penetrates the skin and mucosa
MCQ NO 1211 | GATE 2001
Elastomer used in rubber stopper formulation is
Elastomer used in rubber stopper formulation is
Anonymous Quiz
31%
(a) Polybutadiene
30%
(b) Butyl stearate
15%
(c) Titanium dioxide
24%
(d) Butylated hydroxyl toluene
MCQ NO 1212 | GATE 2001
Schedule D as per D & C Act is concerned with
Schedule D as per D & C Act is concerned with
Anonymous Quiz
63%
(a) List of drugs exempted from the provision of import of drugs
26%
(b) Diseases or aliments which a drug may not purport to prevent or cure
5%
(c) Requirements of factory premises
5%
(d) List of prescription drugs
MCQ NO 1213 | GATE 2001
Official method for the analysis of Ciprofloxacin is by
Official method for the analysis of Ciprofloxacin is by
Anonymous Quiz
15%
(a) Potentiometry
44%
(b) HPLC
26%
(c) Gas Chromatography
15%
(d) Non-aq. titration
MCQ NO 1214 | GATE 2001
The radiofrequency radiation is associated with
The radiofrequency radiation is associated with
Anonymous Quiz
15%
(a) Light consisting of one colour only
55%
(b) Nuclear Magnetic Resonance
21%
(c) Mass Spectrometry
9%
(d) ESR
MCQ NO 1215 | GATE 2001
How many grams of drug should be used in preparing 500 ml of a 1:2500 solution
How many grams of drug should be used in preparing 500 ml of a 1:2500 solution
Anonymous Quiz
30%
(a) 0.2
38%
(b) 0.02
16%
(c) 0.4
16%
(d) 1.25
MCQ NO 1215 | GPAT 2001
The pyroelectric detector converts electromagnetic radiation into
The pyroelectric detector converts electromagnetic radiation into
Anonymous Quiz
49%
(a) Electrical Signal
28%
(b) Fluoroscence
14%
(c) Electrons
8%
(d) Visible light
MCQ NO 1216 | GPAT 2001
The mechanism of Digitalis is
The mechanism of Digitalis is
Anonymous Quiz
10%
(a) Decreases intracellular Na concentration
60%
(b) Inhibits Na-K ATPase
21%
(c) Activated adenyl cyclase which produces c-AMP
8%
(d) Decreased Release of Calcium from Sarcoplasmic reticulum
MCQ NO 1217 | GPAT 2001
The mechanism of action for Dactinomycin is
The mechanism of action for Dactinomycin is
Anonymous Quiz
33%
(a) Inhibits Topoisomerase II
20%
(b) Cross links DNA
31%
(c) Inhibits functions of microtubules
16%
(d) Inhibits DNA Polymerase
MCQ NO 1218 | GPAT 2001
One of the drugs when coadministered with Terfenadine may lead to life threatening Cardiac dysarhythmia
One of the drugs when coadministered with Terfenadine may lead to life threatening Cardiac dysarhythmia
Anonymous Quiz
15%
(a) Lomafloxacine
41%
(b) Clofazimine
32%
(c) Itraconazole
11%
(d) Neomycin
MCQ NO 1219 | GPAT 2001
Adverse effects of one of the drug include amenorrhea, bone marrow depression gastrointestinal distress and haemorrhagic distress. Identify?
Adverse effects of one of the drug include amenorrhea, bone marrow depression gastrointestinal distress and haemorrhagic distress. Identify?
Anonymous Quiz
8%
(a) Cyclizine
22%
(b) Piroxicam
60%
(c) Cyclophosphamide
10%
(d) Cimetidine
MCQ NO 1220 | GPAT 2001
Varicella zoster is the causative organism for
Varicella zoster is the causative organism for
Anonymous Quiz
42%
(a) Small Pox
19%
(b) Dermatophytosis
31%
(c) Herpes
8%
(d) Infectious mononucleosis
MCQ NO 1221 | GATE 2001
One of the following is confirmed by diagnosis test
One of the following is confirmed by diagnosis test
Anonymous Quiz
24%
(a) Hyperuricemia
34%
(b) Cystic fibrosis
30%
(c) Acute pancreatitis
13%
(d) Hyperlipidemia
MCQ NO 1222 | GATE 2001
The conversion of fructose 1,6-biphosphate to Glyceraldehyde-3-phosphate is catalysed by
The conversion of fructose 1,6-biphosphate to Glyceraldehyde-3-phosphate is catalysed by
Anonymous Quiz
37%
(a) Phosphoglycerate kinase
19%
(b) Enolase
29%
(c) Aldolase
15%
(d) Triose phosphate isomerase
MCQ NO 1223 | GATE 2001
Morphine undergoes microsomal oxidation by
Morphine undergoes microsomal oxidation by
Anonymous Quiz
32%
(a) N-dealkylation
28%
(b) Aromatic hydroxylation
30%
(c) Oxidative deamination
10%
(d) O-dealkylation
MCQ NO 1224 | GATE 2001
SULFASALAZINE is a prodrug that is activated in the intestine by bacterial enzymes. The enzyme responsible is :
SULFASALAZINE is a prodrug that is activated in the intestine by bacterial enzymes. The enzyme responsible is :
Anonymous Quiz
35%
(a) Azoreductase
20%
(b) Choline esterase
34%
(c) Glucuronyl transferase
10%
(d) Amylase