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MCQ NO 876 | Physical pharmacy

The reciprocal of viscosity is called(
Anonymous Quiz
19%
a)surface tension
19%
(b)frictional resistance
59%
(c)fluidity
3%
(d)none of these
MCQ NO 877 | Physical pharmacy

The dimensions in which coefficient of viscosity is expressed are
Anonymous Quiz
31%
(a)mass × length × time–1
41%
(b)mass × length–1 × time–1
21%
(c)mass × length–1 × time
6%
(c)mass–1 × length–1 × time–1
MCQ NO 879 | Physical pharmacy

Which of the following defects results in the decrease of density of crystal
Anonymous Quiz
27%
(a) Schottky defect
33%
(b) Frenkel defect
28%
(c) interstitial defect
11%
(d) impurity defect
MCQ NO 880 | Physical pharmacy

In silicon crystal each atom is covalently bonded to _______ neighbours.
Anonymous Quiz
20%
(a)2
38%
(b)8
25%
(c)6
17%
(d)4
Note.... Thyroid Hormones acts on nuclear receptor belongs to steroid and retinoid superfamily of intracellular receptors.

In contrast to the steroid receptor, the TR resides in the nucleus even in the unliganded inactive state.
👉For detail mechanism you can read Nuclear receptors from General Pharmacology.
🔴 Actions of Thyroid
Hormones🔴

1.Growth and development

2. Intermediary metabolism of Lipids, carbohydrates, Proteins.

3.Calorigenesis

4.CVS ... Heart rate , contractility and cardiac output increases, bounding pulse.

5. Haemopoiesis.....by only T4 treatment.

6.Indirect effect on reproduction.
🔴ADRS OF PROBENECID🔴
Severe
hepatic necrosis
anaphylactoid reactions / Rapid
nephrotic syndrome
aplastic anemia
• hemolytic anemia
• Moderate
• hematuria
• gout
• Mild
• nausea
• vomiting
• fever
• pruritus
• flushing
• alopecia
• polyuria
• headache
• dizziness
🔴INTERACTIONS🔴

➡️Probenecid-

Probenecid inhibits urinary excretion of cephalosporins,sulphonamides,Mtx and indomethacin.
Inhibits biliary excretion of rifampicin.
Pyrazinamide and ethambutol may interfere with uricosuric action of Probenecid.
Probenecid inhibits tubular secretion of nitrofurantoin.
Aspirin blocks uricosuric action of Probenecid.
MCQ NO 881 | Pharmacology

Tick the action mechanism of anticancer drugs belonging to plant alkaloids:
Anonymous Quiz
27%
a) Inhibition of DNA-dependent RNA synthesis
19%
b) Cross-linking of DNA
49%
c) Mitotic arrest at a metaphase
5%
d) Nonselective inhibition of aromatases
MCQ NO 882 | Pharmacology

General contraindications for anticancer drugs are:
Anonymous Quiz
10%
a) Depression of bone marrow
6%
b) Acute infections
15%
c) Severe hepatic and/or renal insufficiency
70%
d) All of the above
MCQ NO 884 | Pharmacology

Tick the anticancer drug belonging to inorganic metal complexes:
Anonymous Quiz
10%
a) Dacarbazine
59%
b) Cisplatin
22%
c) Methotrexate
8%
d) Vincristine
MCQ NO 885 | Pharmacology

Tick the indication for estrogens in oncological practice:
Anonymous Quiz
14%
a) Leukemia
41%
b) Cancer of prostate
39%
c) Endometrial cancer
6%
d) Brain tumors
MCQ NO 886 | Pharmaceutics

85.What will be the freezing point depression of isotonic dextrose solution
Anonymous Quiz
42%
(A)-0.52°C
26%
(B)-0.12°C
25%
(C)-0.09°C
8%
(D-0.58°C
MCQ NO 887| Pharmaceutics

In relation to blood plasma ,large volume intravenous injections should be
Anonymous Quiz
64%
(A)isotonic
12%
(B)paratonic
16%
(C)hypotonic
8%
(D)hypertonic
MCQ NO 888| Pharmaceutics

Co-solvent used in parenteral solutions is
Anonymous Quiz
33%
(A)ethyl alcohol
23%
(B)mannitol
23%
(C)sorbitol
21%
(D)benzyl alcohol