MCQ NO 846 | Pharmacology
Methotrexate has the following attributes except:
Methotrexate has the following attributes except:
Anonymous Quiz
17%
A. It is cell cycle specific and kills cells in the S phase
35%
B. Its toxicity primarily affects bone marrow and epithelial structures
31%
C. Folic acid reverses its toxic effects
17%
D. It is the drug of choice for choriocarcinoma
MCQ NO 847 | Pharmacology
The following antineoplastic drug is a mitotic inhibitor and causes metaphase arrest:
The following antineoplastic drug is a mitotic inhibitor and causes metaphase arrest:
Anonymous Quiz
16%
A. Busulfan
55%
B. Vincristine
19%
C. Cytarabine
10%
D. Procarbazine
MCQ NO 848 | Pharmacology
Vinca alkaloids exert antitumor activity by:
Vinca alkaloids exert antitumor activity by:
Anonymous Quiz
18%
A. Activating topoisomerase II to cause breaks in DNA strands
12%
B. Crosslinking DNA strands
17%
C. Inhibiting DNA mediated RNA synthesis
53%
D. Inhibiting polymerization of tubulin to form intracellular microtubules
MCQ NO 849 | Pharmacology
The following cytotoxic drug acts by inhibiting depolymerization of tubulin and thus producing abnormal arrays of microtubules:
The following cytotoxic drug acts by inhibiting depolymerization of tubulin and thus producing abnormal arrays of microtubules:
Anonymous Quiz
25%
A. Paclitaxel
52%
B. Vinblastine
15%
C. Etoposide
8%
D. Mitoxantrone
MCQ NO 850 | Pharmacology
Vincristine differs from vinblastine in the following respect(s):
Vincristine differs from vinblastine in the following respect(s):
Anonymous Quiz
14%
A. Its prominent adverse effect is neuropathy
12%
B. It frequently produces alopecia
17%
C. It does not significantly depress bone marrow
57%
D. All of the above
MCQ NO 851 | Pharmacology
What is true of docetaxel:
What is true of docetaxel:
Anonymous Quiz
20%
A. It is used as a reserve drug for refractory breast and ovarian cancer
22%
B. It is a selective estrogen receptor modulator used for breast cancer
10%
C. It is effective only in estrogen receptor positive breast cancer
48%
D. Both 'B' and 'C' are correct
MCQ NO 852 | Pharmacology
Choose the correct statement about topotecan:
Choose the correct statement about topotecan:
Anonymous Quiz
30%
A. It is a DNA topoisomerase I inhibitor which causes single strand DNA breaks
17%
B. It is a cell cycle specific anticancer drug
16%
C. It is a COMT-inhibitor used in advanced parkinsonism
37%
D. Both 'A' and 'B' are correct
MCQ NO 853 | Pharmacology
The characteristic toxicity of doxorubicin is:
The characteristic toxicity of doxorubicin is:
Anonymous Quiz
18%
A. Kidney damage
26%
B. Liver damage
45%
C. Cardiomyopathy
11%
D. Pulmonary fibrosis
MCQ NO 854 | Pharmacology
Thioguanine differs from mercaptopurine in that:
Thioguanine differs from mercaptopurine in that:
Anonymous Quiz
15%
A. It is not metabolized by xanthine oxidase
17%
B. It does not cause hyperuricemia
22%
C. Its dose need not be reduced when allopurinol is given concurrently
46%
D. Both ‘A’ and ‘C’ are correct
MCQ NO 855 | Pharmacology
Patients treated with the following anticancer drug are likely to develop a disulfiram like reaction on taking alcohol:
Patients treated with the following anticancer drug are likely to develop a disulfiram like reaction on taking alcohol:
Anonymous Quiz
15%
A. Dacarbazine
49%
B. Procarbazine
25%
C. Melphalan
11%
D. Hydroxyurea
MCQ NO 856 | Pharmacology
The following is true about use of prednisolone in malignant diseases except:
The following is true about use of prednisolone in malignant diseases except:
Anonymous Quiz
15%
A. It is curative in acute childhood leukaemia
28%
B. It is used in Hodgkin’s disease
41%
C. It controls hypercalcaemia in patients with bony metastasis
16%
D. It affords symptomatic relief in most cancer patients
MCQ NO 857 | Pharmacology
Select the cell cycle nonspecific antineoplastic drug:
Select the cell cycle nonspecific antineoplastic drug:
Anonymous Quiz
28%
A. Vincristine
29%
B. Bleomycin
20%
C. Methotrexate
23%
D. 5-Fluorouracil
MCQ NO 858 | Pharmacology
Mesna is administered with cyclophosphamide and ifosphamide to:
Mesna is administered with cyclophosphamide and ifosphamide to:
Anonymous Quiz
23%
A. Potentiate their cytotoxic action
22%
B. Retard their renal excretion
26%
C. Block their emetic action
29%
D. Ameliorate cystitis caused by them
MCQ NO 859 | Pharmacology
What is true of thalidomide:
What is true of thalidomide:
Anonymous Quiz
15%
A. It exerts antitumour activity in some solid malignant tumours
18%
B. It ameliorates cancer associated cachexia
10%
C. It exerts antileprotic action
58%
D. All of the above
MCQ NO 860 | Pharmacology
Select the drug which is used exclusively in organ transplantation and autoimmune diseases, but not in cancers:
Select the drug which is used exclusively in organ transplantation and autoimmune diseases, but not in cancers:
Anonymous Quiz
20%
A. Cyclophosphamide
48%
B. Cyclosporine
20%
C. Methotrexate
12%
D. 6-Mercaptopurine
On this 28th of october,
•We are going to announce some new upcoming features of KTA as well as we are introducing a excillent service of KTA.
•We are transforming and migrating our platform.
•We are amended some features and technical issues of KTA services. For implimenting this new amendmets our KTA team is working hard from dawn to dusk.
•We wish that this new changes are benificial for everyone of you.
•It may take some time till then please stay with us and pin the date 28th of october.
Thank You!
•We are going to announce some new upcoming features of KTA as well as we are introducing a excillent service of KTA.
•We are transforming and migrating our platform.
•We are amended some features and technical issues of KTA services. For implimenting this new amendmets our KTA team is working hard from dawn to dusk.
•We wish that this new changes are benificial for everyone of you.
•It may take some time till then please stay with us and pin the date 28th of october.
Thank You!
MCQ NO 861 | Pharmacology
What is true about human interferon α:
What is true about human interferon α:
Anonymous Quiz
26%
A. It is used to treat HIV infection
34%
B. It is used to treat Kaposi‘s sarcoma in AIDS patients
28%
C. It is curative for hepatitis B virus infection
12%
D. It is active orally
MCQ NO 862| Pharmacology
Tick the drug type for which microsomal oxidation is the most prominent:
Tick the drug type for which microsomal oxidation is the most prominent:
Anonymous Quiz
36%
a) Lipid soluble
32%
b) Water soluble
24%
c) Low molecular weight
7%
d) High molecular weight
MCQ NO 863 | Pharmacology
Stimulation of liver microsomal enzymes can:
Stimulation of liver microsomal enzymes can:
Anonymous Quiz
36%
a) Require the dose increase of some drugs
23%
b) Require the dose decrease of some drugs
32%
c) Prolong the duration of the action of a drug
9%
d) Intensify the unwanted reaction of a drug
MCQ NO 864 | Pharmacology
Which of the following local anesthetics is more cardiotoxic?
Which of the following local anesthetics is more cardiotoxic?
Anonymous Quiz
16%
a) Procaine
45%
b) Bupivacaine
32%
c) Lidocaine
8%
d) Mepivacaine