MCQ NO 1306 | Pharmacology
Many xenobiotics are oxidized by cytochrome P450 in order to
Many xenobiotics are oxidized by cytochrome P450 in order to
Anonymous Quiz
10%
(a) Increase their biological activity
25%
(b) Increase their disposition in lipophilic compartments of the body
18%
(c) Increase their aqueous solubility
47%
(d) All of the above
MCQ NO 1307 | Pharmacology
The following protein/polypeptide has a quaternary structure
The following protein/polypeptide has a quaternary structure
Anonymous Quiz
18%
(a) cc-Chymotrypsin
54%
(b) Hemoglobin
20%
(c) Insulin
8%
(d) Myoglobin
MCQ NO 1308 | Pharmacology
Rabies vaccine (living) is prepared using
Rabies vaccine (living) is prepared using
Anonymous Quiz
21%
(a) Sheep blood
20%
(b) Mice lymph
28%
(c) Horse plasma
31%
(d) Fertile eggs
MCQ NO 1309 | Pharmacology
Cyclophosphamide as anticancer agent acts as
Cyclophosphamide as anticancer agent acts as
Anonymous Quiz
20%
(a) Alkylating agent before metabolism
33%
(b) Alkylating agent after metabolism
38%
(c) Phosphorylating agent after metabolism
10%
(d) DNA intercalating agent
MCQ NO 1310 | Pharmacology
Proton pump inhibitors like omeprazole and lansoprazole contain the following ring System:
Proton pump inhibitors like omeprazole and lansoprazole contain the following ring System:
Anonymous Quiz
22%
(a) Pyrimidine
53%
(b) Benzimidazole
20%
(c) Benzothiazole
5%
(d) Oxindole
MCQ NO 1311 | Pharmacology
Methotrexate is.........
Methotrexate is.........
Anonymous Quiz
31%
An alkylating agent
11%
An antibiotic
48%
A folic acid antagonist
11%
A purine antagonist
MCQ NO 1312 | Pharmacology
Fluorouracil belongs to.....
Fluorouracil belongs to.....
Anonymous Quiz
12%
Antibiotics
12%
Plant alkaloids
19%
Bone marrow growth factor
57%
Antimetabolites
MCQ NO 1313 | Pharmacology
Action mechanism of methotrexate is.........
Action mechanism of methotrexate is.........
Anonymous Quiz
6%
Catabolic depletion of serum asparagine
10%
Activation of cell differentiation
51%
Inhibition of dihydrofolate reductase
33%
All of the above
MCQ NO 1314 | Pharmacology
Enzyme drug used for acute leukemia treatment.......
Enzyme drug used for acute leukemia treatment.......
Anonymous Quiz
33%
Asparaginase
40%
Dihydrofolate reductase
14%
Aromatase
13%
DNA gyrase
MCQ NO 1315 | Pharmacology
All of the following drugs are derivatives of nitrosoureas, EXCEPT?
All of the following drugs are derivatives of nitrosoureas, EXCEPT?
Anonymous Quiz
9%
Semustine
17%
Lomustine
68%
Vincristine
6%
Carmustine
MCQ NO 1316 | IP
Which of following are widely used and excellent preservative?
Which of following are widely used and excellent preservative?
Anonymous Quiz
4%
Mercurial
47%
quaternary ammonium compounds
45%
Both
4%
None
MCQ NO 1317 | IP
To increase the viscosity of liquid which of following agents are used?
To increase the viscosity of liquid which of following agents are used?
Anonymous Quiz
13%
Sodium Carboxy Methyl cellulose
10%
PVP
10%
Methyl Cellulose
67%
All of the above
MCQ NO 1318 | IP
Which of the following is widely used flavoring agent in Food Industry ?
Which of the following is widely used flavoring agent in Food Industry ?
Anonymous Quiz
7%
Chloroform
44%
Menthol
41%
Mono Sodium glutamate
8%
None of the above
MCQ NO 1319 | PJ
Cure for cancer in an example of the following advertisements?
Cure for cancer in an example of the following advertisements?
Anonymous Quiz
11%
Bonafide
22%
Exempted
57%
Prohibited
10%
Permitted
MCQ NO 1320 | PJ
Advertisement of prescription drug are meant for (schedule H/G) ........?
Advertisement of prescription drug are meant for (schedule H/G) ........?
Anonymous Quiz
31%
RMP
20%
Patient
45%
Both
4%
None
🔴 Mechanism of Action 🔴
🔺Calcitonin :-
🔸Actions of calcitonin are generally apposite to PTH.
It inhibits bone resorption by direct action on osteoclasts -----decreasing their ruffled surface which forms contact with the resorptive pit.
🔸Calcitonin inhibits oroximal tubular reabsorption of calcium and phosphate by direct action on kidney.
🔸The actions of calcitonin are mediated through a G-protein coupled receptor (CTR) and increase in cAMP formation, but it's target cells are different than PTH.
🔺Calcitonin :-
🔸Actions of calcitonin are generally apposite to PTH.
It inhibits bone resorption by direct action on osteoclasts -----decreasing their ruffled surface which forms contact with the resorptive pit.
🔸Calcitonin inhibits oroximal tubular reabsorption of calcium and phosphate by direct action on kidney.
🔸The actions of calcitonin are mediated through a G-protein coupled receptor (CTR) and increase in cAMP formation, but it's target cells are different than PTH.
MCQ NO 1321 | Pharmacology
Selective COX-2 inhibitors differ from nonselective COX-1/COX-2 inhibitors in that they:
Selective COX-2 inhibitors differ from nonselective COX-1/COX-2 inhibitors in that they:
Anonymous Quiz
47%
a)Are antiinflammatory but not analgesic
15%
b)Do not bring down fever
11%
c)Have no renal effects
27%
d)Do not inhibit platelet aggregation
MCQ NO 1322 | Pharmacology
Inhibitors of prostaglandin synthesis share the following features except:
Inhibitors of prostaglandin synthesis share the following features except:
Anonymous Quiz
20%
a)Prolongation of bleeding time
36%
b)Prolongation of prothrombintime
26%
c)Prolongation of labour
18%
d)Gastric mucosal damage
MCQ NO 1323 | Pharmacology
Inhibition of prostaglandin synthesis does not underlie the following action of aspirin:
Inhibition of prostaglandin synthesis does not underlie the following action of aspirin:
Anonymous Quiz
13%
a)Analgesia
41%
b)Closure of patent duct usarteriosus
29%
c)Hyperventilation
18%
d)Bleeding tendency
MCQ NO 1324 | Pharmacology
………… has nonselective serotonin reuptake inhibitor actions.
………… has nonselective serotonin reuptake inhibitor actions.
Anonymous Quiz
21%
a) Levorphanol
50%
b) Dextromethorphan
21%
c) Dihydroxycodine
8%
d) Ethylmorphi
MCQ NO 1325 | Pharmacology
Meperidine as a potential ………. Agent.
Meperidine as a potential ………. Agent.
Anonymous Quiz
17%
a) Anticholinergic
18%
b) Adrenergic
14%
c) Parasympatholytic
52%
d) Both 1 & 3