MCQ NO 956 | Pharmaceutical Engineering
The operational speed of propeller in mixing is..
The operational speed of propeller in mixing is..
Anonymous Quiz
32%
1000 RPM
38%
8000 RPM
27%
200 RPM
4%
50 RPM
MCQ NO 957 | Pharmaceutical Engineering
Which of the following is mechanism of mixing
Which of the following is mechanism of mixing
Anonymous Quiz
12%
Bulk transport
15%
Turbulent flow
6%
Laminar flow
67%
All of the above
MCQ NO 958 | Pharmaceutics
Tricafos is Proprietary name of _______
Tricafos is Proprietary name of _______
Anonymous Quiz
14%
Calcium Phosphate dibasic
69%
Calcium Phosphate tribasic
13%
Calcium sulphate
5%
Calcium carbonate
MCQ NO 959 | Pharmaceutics
The % concentration of Gelatin used as binder is ___
The % concentration of Gelatin used as binder is ___
Anonymous Quiz
21%
1-3
48%
5-20
22%
1-10
9%
Up to 50
MCQ NO 960 | Pharmacology
Following Drugs are metabolized by CYP2B6 isoenzyme EXCEPT .
Following Drugs are metabolized by CYP2B6 isoenzyme EXCEPT .
Anonymous Quiz
27%
Clopidogrel
27%
Sertraline
23%
Methadone
22%
Halothane
MCQ NO 961 | Pharmacology
The following substances are considered to be referred to as eicosanoids:
The following substances are considered to be referred to as eicosanoids:
Anonymous Quiz
10%
a) Prostaglandins
12%
b) Leukotrienes
14%
c) Thromboxanes
64%
d) All of the above
MCQ NO 962 | Pharmacology
Correct statements about cortisol (hydrocortisone) include all of the following, EXCEPT:
Correct statements about cortisol (hydrocortisone) include all of the following, EXCEPT:
Anonymous Quiz
16%
a) Cortisol is synthesized from cholesterol
20%
b) ACTH governs cortisol secretion
29%
c) Most cortisol is inactivated in the liver
35%
d) The half-life of cortisol in the circulations is normally about 60-90 hours
MCQ NO 963 | Pharmacology
Ranitidine is a___________
Ranitidine is a___________
Anonymous Quiz
59%
a) Proton pump inhibitor
14%
b) Reuptake pump inhibitor
11%
c)Amine pump inhibitor
16%
d)None of above
MCQ NO 964 | Pharmacology
Which of histamine H1 antagonists in noted for the serotonin-blocking effect?
Which of histamine H1 antagonists in noted for the serotonin-blocking effect?
Anonymous Quiz
28%
a. Brompheniramine
51%
b. Cyproheptadine
13%
c. Suprastine
8%
d. Dimedrol
MCQ NO 965 | Pharmacology
All of the following conditions are causes of hypothyroidism except
All of the following conditions are causes of hypothyroidism except
Anonymous Quiz
12%
a) Endemic goiter
39%
b) Surgical excision
32%
c) Gravesโs disease
18%
d) goitrin-induced iodine deficiency
MCQ NO 966 | Pharmacology
Non-narcotic analgesics are mainly effective against pain associated with:
Non-narcotic analgesics are mainly effective against pain associated with:
Anonymous Quiz
12%
Trauma
19%
Myocardial infraction
54%
Inflammation or tissue damage
14%
Surgery
MCQ NO 967 | Pharmacology
Non-narcotic agents cause.........
Non-narcotic agents cause.........
Anonymous Quiz
23%
Respiratory depression
21%
Euphoria
19%
Physical dependence
37%
Antipyretic effect
MCQ NO 968 | pharmacology
Which of the following non-narcotic agents is salicylic acid derivative?
Which of the following non-narcotic agents is salicylic acid derivative?
Anonymous Quiz
10%
Phenylbutazone
16%
Ketamine
70%
Aspirin
4%
Tramadol
MCQ NO 969 | Pharmacology
Non-narcotic analgesics are all of the following drugs EXCEPT:
Non-narcotic analgesics are all of the following drugs EXCEPT:
Anonymous Quiz
17%
Paracetamol
21%
Acetylsalicylic acid
46%
Butorphanol
17%
Ketorolac
MCQ NO 970 | Pharmacology
Which one of the following non-narcotic agents inhibits mainly cyclooxygenase (COX) in CNS?
Which one of the following non-narcotic agents inhibits mainly cyclooxygenase (COX) in CNS?
Anonymous Quiz
21%
Ketorolac
37%
Acetylsalicylic acid
29%
Ibuprofen
14%
Paracetamol
๐ด Mechanism of Action ๐ด
๐บ1. Antiandrogens :-
a. Flutamide :- Non-steroidal AR (androgen receptor)antagonist with no other hormonal activity.
They are now used in conjunction with GnRH agonist or after castration to block the residual action of adrenal androgens as COMBINED ANDROGEN BLOCKED (CAB) therapy of metastatic carcinoma prostate.
b. Bicalutamide :- more potent and linger acting (half life is 6 days) congener of flutamide.
๐บ2. 5-alpha reductase inhibitors
(e.g. Finasteride and Dutasteride)
These drugs are competitive inhibitor of 5 aloha reductase enzyme which converts the Testosterone intomore active Dyhydrotestosterone and gives androgenic action in many tissues.... So, these drugs reduce this effect by blocking the 5-alpha reductase enzyme.
๐บNote...
Finasteride selectively inhibit type 2 isoenzyme 5-alpha reductase.
Dutasteride inhibit both type 1 and type 2 isoenzymes (5-alpha reductase) and inhibit DHT levels.
๐บ1. Antiandrogens :-
a. Flutamide :- Non-steroidal AR (androgen receptor)antagonist with no other hormonal activity.
They are now used in conjunction with GnRH agonist or after castration to block the residual action of adrenal androgens as COMBINED ANDROGEN BLOCKED (CAB) therapy of metastatic carcinoma prostate.
b. Bicalutamide :- more potent and linger acting (half life is 6 days) congener of flutamide.
๐บ2. 5-alpha reductase inhibitors
(e.g. Finasteride and Dutasteride)
These drugs are competitive inhibitor of 5 aloha reductase enzyme which converts the Testosterone intomore active Dyhydrotestosterone and gives androgenic action in many tissues.... So, these drugs reduce this effect by blocking the 5-alpha reductase enzyme.
๐บNote...
Finasteride selectively inhibit type 2 isoenzyme 5-alpha reductase.
Dutasteride inhibit both type 1 and type 2 isoenzymes (5-alpha reductase) and inhibit DHT levels.
๐ดADRS OF ANTIANDROGENS๐ด
โ๏ธAndrogenic anabolism is suppressed
โ๏ธGynacosmastia
โ๏ธBreast tenderness
โ๏ธLiver damage occures frequently
โ๏ธSkin rashes
โ๏ธSwelling of lips
โ๏ธAndrogenic anabolism is suppressed
โ๏ธGynacosmastia
โ๏ธBreast tenderness
โ๏ธLiver damage occures frequently
โ๏ธSkin rashes
โ๏ธSwelling of lips
MCQ NO 971 | Pharmaceutical jurisprudence
Licence to manufacture for sale Homoeopathic Medicine specified in
Licence to manufacture for sale Homoeopathic Medicine specified in
Anonymous Quiz
23%
A. 25A
31%
B. 25D
24%
C. 25E
22%
D. 21A
MCQ NO 972 | Pharmaceutical jurisprudence
Education institutions providing pharmacy education are approved by the?
Education institutions providing pharmacy education are approved by the?
Anonymous Quiz
11%
A. Central government
83%
B. Pharmacy council of India
4%
C. Drug Controller of India
2%
D. None of these
MCQ NO 973 | Pharmaceutical jurisprudence
Medical stores are inspected by drug inspector for at least
Medical stores are inspected by drug inspector for at least
Anonymous Quiz
29%
A. Once a year
53%
B. Twice in a year
15%
C. Thrice in a year
4%
D. Quarterly in a yea
MCQ NO 974 | pharmaceutical jurisprudence
Which symbol is used on the left hand top corner of the label of schedule 'X'
Which symbol is used on the left hand top corner of the label of schedule 'X'
Anonymous Quiz
13%
A. R.M.P.
26%
B. b.Rx
56%
C. XRx
5%
D. None of these