In which condition is hepcidin low?

What is the expected MCV in untreated hereditary hemochromatosis?

Which test reliably distinguishes ACD from IDA in a patient with chronic inflammation?

A 30-year-old woman with heavy menstrual bleeding has fatigue, pallor, and ice cravings. Labs: Hb 9.0 g/dL (↓), MCV 72 fL (↓), serum iron 30 mcg/dL (↓), TIBC 480 mcg/dL (↑), ferritin 8 ng/mL (↓).
Question: What is the most likely diagnosis?

A 60-year-old man with rheumatoid arthritis and elevated CRP has Hb 10.5 g/dL (↓), MCV 85 fL, serum iron 40 mcg/dL (↓), TIBC 250 mcg/dL (↓), ferritin 350 ng/mL (↑).
Question: Why is TIBC low?

A 45-year-old with Crohn’s disease and GI bleeding has Hb 8.5 g/dL (↓), MCV 78 fL (↓), serum iron 25 mcg/dL (↓), TIBC 400 mcg/dL (↑), ferritin 120 ng/mL (↑), CRP 50 mg/L (↑).
Question: Which test confirms iron deficiency?

A 12-year-old boy with lifelong microcytic anemia unresponsive to oral iron has Hb 8.8 g/dL (↓), MCV 68 fL (↓), serum iron 20 mcg/dL (↓), TIBC 500 mcg/dL (↑), ferritin 15 ng/m

A child with microcytic anemia unresponsive to oral iron has serum iron 25 mcg/dL (↓), TIBC 480 mcg/dL (↑), ferritin 20 ng/mL (↓), ↑ hepcidin.
Question: Why is oral iron ineffective?

A 10-year-old child with lifelong microcytic anemia unresponsive to oral iron has:

Serum Iron: 18 µg/dL (Low) TIBC: 450 µg/dL (Normal) TSAT: 4% (Very Low) Ferritin: 50 µg/L (Normal) MCV: 68 fL (Low) Question: What disorder is suspected?

Case: A 30-year-old woman with menorrhagia has fatigue and pallor. Labs:

Hb: 8.8 g/dL (↓) MCV: 70 fL (↓) Serum Iron: 20 µg/dL (↓) TIBC: 500 µg/dL (↑) Ferritin: 12 µg/L (↓) Question: Which parameter confirms IDA?

Which lab pattern is typical of IRIDA?

Case: A patient with IRIDA has:

MCV: 65 fL (↓) Ferritin: 60 µg/L (normal) TSAT: 5% (↓↓) Question: Why is the MCV low?

Question: Which condition is associated with low TIBC?

What does a low ACTH level with high cortisol indicate in the ACTH test?

Which of the following is one of the confirmatory tests for Cushing’s syndrome?

Which of the following is a common skin manifestation in Cushing’s syndrome?

What is the mechanism behind hypertension in Cushing’s syndrome?

What is the reason for hyperglycemia in patients with Cushing’s syndrome?

Which of the following symptoms is NOT typically seen in Cushing’s syndrome?

Which of the following lab findings supports a diagnosis of Cushing's syndrome?

A patient with Cushing’s syndrome presents with proximal muscle weakness and easy bruising. What is the most likely mechanism?