أين يوجد معظم حديد الجسم؟
Anonymous Quiz
6%
المايوغلوبين
4%
الإنزيمات
48%
الهيموغلوبين
43%
الفيريتين
لماذا يعتبر الحديد من المصادر الحيوانية (Heme Iron) أفضل من المصادر النباتية؟
Anonymous Quiz
13%
لأنه يحتوي على فيتامين C
50%
لأن امتصاصه أعلى في الامعاء
17%
لأنه لا يتأثر بحمض المعدة
20%
لأنه لا يحتاج إلى بروتينات ناقلة
ما الآلية الأساسية التي يُنظم بها الهيبسيدين (Hepcidin) مستويات الحديد في الدم؟
Anonymous Quiz
11%
يزيد امتصاص الحديد في الأمعاء
71%
يسبب تحطيم بروتين Ferroportin 1، مما يقلل إطلاق الحديد من الخلايا
16%
يحفز تخزين الحديد في الكبد
1%
يزيد إفراز الحديد عن طريق ال Urine
كم ملغم يوميا تفقد النساء قبل سن اليأس
Anonymous Quiz
33%
1 ملغم
44%
1.5 ملغم
15%
2 ملغم
8%
2.5 ملغم
What is the primary regulator of iron absorption in the intestines?
Anonymous Quiz
30%
A) Transferrin
40%
B) Hepcidin
20%
C) Ferritin
10%
D) Hemoglobin
Transferrin saturation (TSAT) is calculated by which formula?
Anonymous Quiz
43%
A) (Serum Iron / TIBC) × 100
26%
B) (TIBC / Serum Iron) × 100
21%
C) (Ferritin / Serum Iron) × 100
10%
D) (Serum Iron / Ferritin) × 100
A patient has the following lab results:
Low serum iron
High TIBC Low transferrin saturation Low ferritin What is the most likely diagnosis?
Low serum iron
High TIBC Low transferrin saturation Low ferritin What is the most likely diagnosis?
Anonymous Quiz
16%
A) Anemia of chronic disease
65%
B) Iron deficiency anemia
10%
C) Hemolytic anemia
9%
D) Thalassemia
👍2
Which of the following best represents Total Iron Binding Capacity (TIBC)?
Anonymous Quiz
37%
A) The amount of iron bound to transferrin
20%
B) The total iron stored in ferritin
37%
C) The total number of available binding sites on transferrin
7%
D) The amount of iron
Ferritin is a marker of:
Anonymous Quiz
9%
A) Circulating iron in the blood
14%
B) Iron bound to transferrin
66%
C) Total body iron stores
11%
D) Iron absorption in the gut
In iron deficiency anemia, what happens to TIBC?
Anonymous Quiz
24%
A) Decreases
56%
B) Increases
7%
C) Remains normal
13%
D) First increases, then decreases
Which condition would NOT typically cause iron deficiency anemia?
Anonymous Quiz
22%
A) Chronic blood loss (e.g., menorrhagia)
22%
B) Malabsorption (e.g., celiac disease)
21%
C) Increased hepcidin due to inflammation
35%
D) Excessive red meat consumption
A patient with low serum iron, low TIBC, and high ferritin likely has:
Anonymous Quiz
22%
A) Iron deficiency anemia
42%
B) Anemia of chronic disease
21%
C) Hemochromatosis
15%
D) Lead poisoning
Which finding is not typical of iron deficiency anemia?
Anonymous Quiz
24%
A) Koilonychia (spoon-shaped nails)
44%
B) High reticulocyte count
17%
C) Pica (craving ice/dirt)
15%
D) Fatigue
What is the first lab test to become abnormal in early iron deficiency?
Anonymous Quiz
34%
A) Hemoglobin
31%
B) Ferritin
16%
C) MCV
19%
D) Serum iron
👍1
In which condition is hepcidin low?
Anonymous Quiz
10%
A) ACD
56%
B) Hereditary Hemochromatosis
18%
C) IRIDA
16%
D) IDA
What is the expected MCV in untreated hereditary hemochromatosis?
Anonymous Quiz
30%
A) Normal (80–100 fL)
38%
B) Low (<80 fL)
19%
C) High (>100 fL)
12%
D) Variable
Which test reliably distinguishes ACD from IDA in a patient with chronic inflammation?
Anonymous Quiz
13%
A) Serum Iron
44%
B) Soluble Transferrin Receptor (sTfR)
30%
C) TIBC
13%
D) MCV
A 30-year-old woman with heavy menstrual bleeding has fatigue, pallor, and ice cravings. Labs: Hb 9.0 g/dL (↓), MCV 72 fL (↓), serum iron 30 mcg/dL (↓), TIBC 480 mcg/dL (↑), ferritin 8 ng/mL (↓).
Question: What is the most likely diagnosis?
Question: What is the most likely diagnosis?
Anonymous Quiz
16%
A) Anemia of chronic disease
71%
B) Iron deficiency anemia
6%
C) Thalassemia
6%
D) Hemochromatosis
A 60-year-old man with rheumatoid arthritis and elevated CRP has Hb 10.5 g/dL (↓), MCV 85 fL, serum iron 40 mcg/dL (↓), TIBC 250 mcg/dL (↓), ferritin 350 ng/mL (↑).
Question: Why is TIBC low?
Question: Why is TIBC low?
Anonymous Quiz
19%
A) Iron overload
60%
B) Chronic inflammation
13%
C) Hemolysis
8%
D) Vitamin B12 deficiency
👍1
A 45-year-old with Crohn’s disease and GI bleeding has Hb 8.5 g/dL (↓), MCV 78 fL (↓), serum iron 25 mcg/dL (↓), TIBC 400 mcg/dL (↑), ferritin 120 ng/mL (↑), CRP 50 mg/L (↑).
Question: Which test confirms iron deficiency?
Question: Which test confirms iron deficiency?
Anonymous Quiz
18%
A) Serum iron
53%
B) Soluble transferrin receptor (sTfR)
21%
C) TIBC
9%
D) CRP