Haramaya University Hiwot Fana Comprehensive Specialized Hospital Drug Information Service (HrU-HFCSH DIS)
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In patients with AHF, a combination diuretic strategy improved early decongestion without affecting prognosis.

The use of SGLT2i during index hospitalization was associated with an improvement in all-cause mortality and HF events.


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Effect of exersise on depression. A Systematic review and meta analysis finding summary from BMJ.


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Understanding the Frontline Battle Against Antibiotic Resistance

Antimicrobial resistance (AMR) is one of the greatest public health threats of our time - silently spreading across hospitals, communities, and even our daily prescribing habits. Every year, resistant infections cost millions of lives and billions in healthcare burden.

Key takeaways for clinicians & pharmacists:

👉Always culture before treating
👉Use the narrowest effective antibiotic possible
👉Optimize dosing based on PK/PD
👉Avoid unnecessary dual coverage
👉Review and de-escalate therapy early
👉Educate patients on adherence and resistance prevention


When we apply stewardship with precision, we not only treat infections we protect the power of antibiotics for future generations.


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Intravenous antibiotics are often continued far longer than necessary — not because patients need them, but because the decision to switch is delayed.

IV-to-oral (IV-PO) switch is one of the simplest, safest, and most effective antimicrobial stewardship interventions, yet it remains widely underutilised.

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Why we need to talk about the "Cipro-NSAID" connection.
 
There is a potentially dangerous interaction between floroquinolones and NSAIDs

THE MECHANISM
Fluoroquinolones can inhibit GABA-our brain's primary inhibitory neurotransmitter. When you add an NSAID into the mix, this effect is amplified.

THE RISK
This synergy doesn't just cause "jitters." It significantly lowers the seizure threshold and can lead to severe CNS excitation, tremors, or anxiety-even in patients with no history of neurological issues.

PRACTICAL RECOMMENDATIONS
1.      Avoid unnecessary NSAID use during fluoroquinolone therapy.
2.      Use Paracetamol when appropriate.
3.      Monitor for CNS symptoms.
4.      Use caution in patients with seizure disorders or kidney disease.

Let's keep patient safety at the forefront of our counselling.

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What is new in 2026 GINA asthma Guideline ?

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