✍Treatment of carcinoid tumor:-
👉1. Octreotide
👉2. Methylsergide or cyprohyptidine

👉Treatment of hepatic disease
1. Neomycin
2. Rifaximine افضل

choose the best answer
torsade de point is treated by
1)Epsom salt
2) paraffin oil
3)lidocaine
4) loperamide
answer(1)because the Epsom salt is the other name of magnesium sulfate
#فارما

👉Digoxin indicated for :-
1- HF (⬆ contractility)

2- Supra ventricular arrhythmias " atrial fibrillation" (⬇️conduction at AV node and depression of SA node)

👉Hydralazine coadministered with a β-blocker to prevent reflex tachycardia.

👉Verapamil
often causes constipation, probably by blocking L-type calcium channels in the colon.

Alkaloid drugs
(أدوية قاعدية تستخرج من النباتات)
1- hyocine (scopolamine)
2- Atropin
3- Morphine
4- Colchicine

نقطة مهمة الدكتور ركز عليه
👉Patient has Gout with liver disease treated by ALLOPURINOL.

👉Patient has Gout with renal disease treated by FEBUXOSTAT.

👉NSAIDs or intra articular corticosteroids (prednisolone ) are the usual first-line treatment for acute gout.

Guanethidine (Guanadril) :- inhibit the release of catecholamines from the presynaptic neuron.
👉Use for treatment of
1- hypertension and
2- eye drop for exophthalmous in hyperthyroidism.

👉PREECLAMPSIA & ECLAMPSIA .

📍Symptoms
P 1- Proteinuria
R 2- Rising blood pressure (hypertension )
E 3- Edema
4- hypoalbuminemia.

📍Treatment
1- hydralazine
2- labitalol
3- magnesium sulfate. DOC

🙂Magnesium hydroxide (antacid)
has a strong laxative effect which ,use treatment of gastric ulcer with Constipation.

🙃 aluminum hydroxide (antacid)
has a constipating action which use in treatment of gastric ulcer with diarrhea.

😉A helpful mnemonic is magnesium “magnifies” stool, aluminum hALts the stool.

🙂Alosetron
a potent 5-HT3 antagonist, is approved for treatment of women with severe Irritable bowel syndrome with diarrhea.

🙃Lubiprostone
a laxative that activates the type 2 chloride channels in the small intestine, is approved for treatment of women with Irritable bowel syndrome with predominant constipation.

✍Raynaud's phenomenon treated by :-

👉1- Prostacyclin (also called prostaglandin I2 or PGI2)derivatives like (EPOPROSTENOL & ILIOPROST)

👉2- alpha blockers like (PRAZOCINE...)

👉3- calcium channel blockers, such as the dihydropyridines NIFEDIPINE or AMLODIPINE, preferably slow release preparations – are often first line treatment.

✍Pulmonary hypertension drugs :-

👉1- Sildenafil ➡Inhibits PDE-5 .

👉2- Epoprostenol, iloprost PGI2 (prostacyclin) derivatives.

👉3- BosENtan &Amprezantan Competitively antagonizes ENdothelin receptors ➡ decrease pulmonary vascular resistance.

🙈treatement of cyanide poisoning

1)sodium nitrate
2) sodium thiosulfate
3)I.V vitamine C
4) methylene blue 1-2 mg/kg as Emergency and given Intravenously

5) hydroxycobalamine is the most recently developed cyanide antidot.

👉Asprin should not be used
in atrial fibrillation because asprin can,t prevent embolic stroke and it is associated by bleeding risk .


👉To treat thromboembolism in atrial fibrillation we use warfarin,factor X inhibitors(rivaroxaban), thrombin inhibitor ( dabigatran)

👉β-blockers (ACEBUTOLOL and PINDOLOL:-
Antagonists with partial agonist activity are NOT USED for stable angina or arrhythmias due to their partial agonist effect.

✍Pyridoxine/doxylamine (غير آمن)

📍is a combination of PYRIDOXINE hydrochloride (vitamin B6) and DOXYLAMINE succinate (antihistamine).

📍prescribed for the management of nausea and vomiting of pregnancy (morning sickness).

👌PROMETHAZINE or MECLIZINE with VITAMIN B6 also used for morning sickness .(آمن وأفضل )

🙊غثيان المرأة الحامل يكون مصاحب بنقصان B6 لذلك نعطي vitamin B6 مع علاج الغثيان .

✍Hypertension in
pregnancy drugs:-

1-Hydralazine
2- labetalol
3- methyldopa
4- nifedipine.

👉the first-line therapy for hypertension in pregnancy is :-

🙈hydralazine is used for pregnancy induced hypertension (during pregnancy ).

🙈 Methyldopa is used for pregnant women who was hypertensive.

✍Hypertensive
emergency drugs :-

👉Treat with
1-clevidipine
2- fenoldopam
3- labetalol
4- nicardipine
5- nitroprusside.

✍B-blockers which used in treatment of heart failure 👉MBC
●Metoprolol
●Bisoprolol
●Carvedilol

✍Adenosine used as a first choice for treatment of paroxysmal Supraventricular tachycardia

👌Phenylephrine also used .

Arrhythmias drugs for different arrhythmia :
💊Propranolol is treatment the arrhythmia that cause by hyperthyrodism

💊Lidocaine: is treatment the arrhythmia that cause by digitalis

💊Flecainide: is treatment arrhythmia of wolff parkinson white syndrome


💊Magnesium sulfalte: is treatment the digitalis arrhythmia and arrhythmia of (Torsade de point)


#Group_Four
هاشم السواري#

👨‍⚕Osteoarthritis...advised to weight loss

👨‍⚕Systemic lopus erythematosus(SLE)...avoid sun light

👨‍⚕Reiter's diseases...advised to rest

👨‍⚕ankylosing spondylitis ...advised to exercise

👨‍⚕septic arthritis...avoid prolonged rest

👨‍⚕systemic scleromderma(s s)....avoid exposure to cold

Related to pharmalogy

#Groub_Four

🙈Thiazide diuretics Toxicity can remember by HyperGLUC; hyperGlycemia, hyperLipidemia, hyperUricemia and hyperCalcemia.