📌متن ویدئو ۱.۷
@Medterms
@Essential_Biochemistry

2⃣.1⃣

🔘Draw the structure of amino acids.

🔘Describe and rank the interatomic forces that give proteins and amino acids their shapes.

🔘Predict whether functional groups on an amino acid will be protonated or deprotonated at physiological pH.

🔘Predict the conformational diversity of the R groups of different amino acids.

🔘Classify amino acids based upon the properties of their R groups (e.g. by size, polarity, charge, or chemically unique properties).

@Medterms
@Essential_Biochemistry

🧬Trust me i'm a biologist
به من اعتماد کن...من یه زیست شناسم

۱۶‌آوریل در برخی کشورها به عنوان روز زیست شناس شناخته میشود

بنابراین جا دارد ما نیز از این فرصت استفاده کرده و روز زیست شناس را تبریک بگوییم❤️

@medterms
@cytology
@essential_biochemistry
@edu_consult

🎥یک ویدیوی فوقالعاده از آنزیم DNA gyrase مشغول کار, و به دنبال اون هم انزیم پلیمراز رو میبینیم که مشغول همانند سازی هست

Dna gyrase at work to uncoil a dna double helix

🎞Dna gyrase
آنزیم باز کننده و ریلکس کننده ی DNA
🎞Uncoil
باز کردن درهم پیچدگی
🎞Double helix
مارپیچ دو رشته ای

@medterms
@cytology
@essential_biochemistry

📌متن ویدئو ۲.۱
@Medterms
@Essential_Biochemistry

2⃣.2⃣

🔘Label the atoms and bonds in a polypeptide.

🔘Recognize the unique properties of each of the bonds in a polypeptide chain.

🔘Describe a Ramachandran plot and how it is generated.

🔘Identify the three secondary structures of proteins.

🔘Predict the secondary structure of a polypeptide based on its phi and psi angles.

🔘Explain how hydrogen bonding contributes to the formation of secondary structure.

@Medterms
@Essential_Biochemistry

📌متن ویدئو ۲.۲
@Medterms
@Essential_Biochemistry

2⃣.3⃣

🔘Explain the difference between a motif, fold and domain.

🔘Describe why there is a limited diversity of different protein folds.

@Medterms
@Essential_Biochemistry

📌متن ویدئو ۲.۳
@Medterms
@Essential_Biochemistry

2⃣.4⃣

🔘Describe the main #forces that determine the folding of proteins.

🔘Summarize how these forces balance in magnitude to promote #protein #folding.

@Medterms
@Essential_Biochemistry

📌متن ویدئو ۲.۴
@Medterms
@Essential_Biochemistry

2⃣.5⃣
🔘Summarize the thermodynamic hypothesis.

🔘Explain how Anfinsen's experiment supports the thermodynamic hypothesis.

🔘Explain how folding funnels are used to visualize protein folding thermodynamics.

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@Essential_Biochemistry

📌متن ویدئو۲.۵
@Medterms
@Essential_Biochemistry

2⃣.6⃣
🔘Explain the role of cooperativity in protein folding.

🔘Summarize the theoretical basis of Levinthal's paradox.

🔘Describe the diffusion collision and nucleation condensation models of protein folding.

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@Essential_Biochemistry

📌متن ویدئو۲.۶
@Medterms
@Essential_Biochemistry

2⃣.7⃣
🔘Explain why there is a risk of aggregate formation for proteins folding in the cytosol.

🔘Summarize how different chaperones function to prevent protein aggregation.

🔘Explain why heat shock causes protein aggregation.

🔘Compare the chaperone function of HSP70 and HSP60.

@Medterms
@Essential_Biochemistry

📌متن ویدئو۲.۷
@Medterms
@Essential_Biochemistry

3⃣.1⃣

🔘Define reaction equilibrium

🔘Determine if a reaction is spontaneous based on the free energy of the reaction coordinates.

🔘Explain how a catalyst reduces the activation energy to speed the rate of a reaction.

🔘Understand that an enzyme stabilizes a transition state to decrease the activation energy of a reaction.

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@Essential_Biochemistry

📌متن ویدئو۳.۱
@Medterms
@Essential_Biochemistry

3⃣.2⃣

🔘Recall that transient covalent bonds position the substrate in the enzyme active site to reduce the entropy of the system.

🔘Explain how weak non-covalent interactions (i.e. binding energy) reduce activation energy.

🔘Contrast Emil Fischer's lock-and-key model of enzyme specificity with the 'induced fit' hypothesis of enzyme catalysis.

🔘Define desolvation as it relates to binding energy.

#Enzyme #Catalysis

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@Essential_Biochemistry

📌متن ویدئو۳.۲
@Medterms
@Essential_Biochemistry