(1/2) Case of a multiple myeloma patient (a 61-year-old man) who developed severe #COVID19 10 weeks after his 2nd dose of the #CovidVaccine (Moderna): https://www.sciencedirect.com/science/article/pii/S2590170221000674?via%3Dihub
An "extensively mutated form of the B.1.628 variant (24 canonical mutations)" was detected.

(2/2) - Since Sept. 2020 he took ixazomib, lenalidomide & methylprednisolone
- Two specific spike mutations (N440K & E484Q) were detected
- N440K has been observed in viral passaging experiments (https://nature.com/articles/s41586-021-03324-6)
- Were the mutations created in his body?

There is now a significant excess mortality in Europe in the age group 15-44 years: https://www.euromomo.eu/graphs-and-maps
The #Covid19-associated deaths alone cannot explain the increase.
A predictable development.

"Even serum from persons vaccinated & boosted with mRNA-based vaccines exhibited substantially diminished neutralizing activity against B.1.1.529" (#Omicron): https://www.nature.com/articles/d41586-021-03826-3
"The Omicron variant presents a serious threat to many existing #COVID19 vaccines ..."

Something is not quite right with the #COVID19 data.
This study found devitations from Benford’s distribution in #COVID19 data from Europe: https://www.medrxiv.org/content/10.1101/2021.12.24.21268373v1
Such deviations are indications form data manipulation.

"... the risk of myocarditis following vaccination is consistently higher [compared to #COVID19-induced myocarditis] in younger males, particularly following a 2nd dose of mRNA-1273 vaccine (Moderna)."
https://www.medrxiv.org/content/10.1101/2021.12.23.21268276v1

"Vitamin D deficiency was found in 82.2% of COVID-19 cases and 47.2% of population-based controls (p<0.0001)"
https://academic.oup.com/jcem/article/106/3/e1343/5934827
#COVID19 #vitaminD

Vitamin D alters the epigenetic landscape of CD4+ T cells & induce key transcription factors such as STAT3, BACH2 & JUN
⇒ Decrease of IFN-γ & increase IL-10
⇒ Generation of pro-resolving TH1 cells (beneficial in resolving or preventing severe #COVID19)
https://www.nature.com/articles/s41590-021-01098-7

Vitamin D deficiency is associated with mortality in patients with critical #COVID19:
https://e-nrp.org/DOIx.php?id=10.4162/nrp.2021.15.S1.S32
"Vitamin D deficiency was present in 84% of critical COVID-19 patients. Serum 25(OH)D was independently associated with mortality in critical patients with COVID-19."

"We found a significant direct association between vitamin D deficiency and elevated risk of COVID-19 in-hospital mortality. Moreover, each unit increment in serum vitamin D levels was associated to significant reduction in risk of #COVID19 mortality."
https://www.tandfonline.com/doi/abs/10.1080/10408398.2021.2012419?journalCode=bfsn20

- "Based on our observations, quercetin is safe and effective in lowering the serum levels of ALP, q-CRP, and LDH as critical markers involved in #COVID19 severity."
- "Quercetin has shown therapeutic benefits in severe COVID-19."
https://www.sciencedirect.com/science/article/pii/S0014299921007718?via%3Dihub