Omicron like Variant?? Check this out-
https://www.cnn.com/2022/03/02/health/divergent-new-variant-deer/index.html
https://www.cnn.com/2022/03/02/health/divergent-new-variant-deer/index.html
There is one report that discusses the integration of target–ligand blocking with a previously described B cell receptor-sequencing approach (linking B cell receptor to antigen specificity through sequencing (LIBRA-seq)) enabling the rapid and efficient identification of multiple neutralizing mAbs that prevent the binding of SARS-CoV-2 spike (S) protein to angiotensin-converting enzyme 2 (ACE2).
Read full paper on: https://www.nature.com/articles/s41587-022-01232-2
Read full paper on: https://www.nature.com/articles/s41587-022-01232-2
Nature
Efficient discovery of SARS-CoV-2-neutralizing antibodies via B cell receptor sequencing and ligand blocking
Nature Biotechnology - B cell receptor sequencing with ligand blocking speeds up neutralizing antibody discovery.
Interested in learning how you can contribute in tackling COVID-19 Pandemic? Here, we offer an online workshop on this topic with expert speakers and live demo sessions. Check out www.dollareducation.org
💥 Bioinformatics Applications in Tackling COVID-19 Pandemic💥
🗓 Date: 14 March - 24 March, 2022
⏰ Time: 6:00 pm IST
✍️ Registration Link
https://www.dollareducation.org
💲 Fees: Rupees 1200 for Indian Participants /USD 25 for international Participants
💥Topics:
▫️Bioinformatics Resources
▫️Quick designs of vaccines
▫️Determining pre-existing immunity
▫️SARS-CoV2 Genomics
▫️Detecting lineages and variants of concerns
▫️Genomic evaluation
▫️Drug-repurposing
ℹ️Contact and More information:
https://t.me/+qCL0SBRZSLZmMDE1
💥 Bioinformatics Applications in Tackling COVID-19 Pandemic💥
🗓 Date: 14 March - 24 March, 2022
⏰ Time: 6:00 pm IST
✍️ Registration Link
https://www.dollareducation.org
💲 Fees: Rupees 1200 for Indian Participants /USD 25 for international Participants
💥Topics:
▫️Bioinformatics Resources
▫️Quick designs of vaccines
▫️Determining pre-existing immunity
▫️SARS-CoV2 Genomics
▫️Detecting lineages and variants of concerns
▫️Genomic evaluation
▫️Drug-repurposing
ℹ️Contact and More information:
https://t.me/+qCL0SBRZSLZmMDE1
Have you seen this ?
Blood Proteins That Could Increase Risk of Severe COVID
https://www.sciencealert.com/giant-study-identifies-blood-proteins-that-could-increase-risk-of-severe-covid-19/amp
Blood Proteins That Could Increase Risk of Severe COVID
https://www.sciencealert.com/giant-study-identifies-blood-proteins-that-could-increase-risk-of-severe-covid-19/amp
ScienceAlert
Huge Study Finds Blood Proteins That Could Increase Risk of Severe COVID
Multiple factors play a role in complex diseases like COVID, and knowing what they are is important for predicting how different people will be affected.
Do you know about IEDB?
IEDB extends across immune epitope data related to all species studied and includes an antibody, T cell, and MHC binding contexts associated with infectious, allergic, autoimmune, and transplant-related diseases.
Explore the database on www.iedb.org
For more information, check out this paper- https://academic.oup.com/nar/article/47/D1/D339/5144151?login=true
IEDB extends across immune epitope data related to all species studied and includes an antibody, T cell, and MHC binding contexts associated with infectious, allergic, autoimmune, and transplant-related diseases.
Explore the database on www.iedb.org
For more information, check out this paper- https://academic.oup.com/nar/article/47/D1/D339/5144151?login=true
OUP Academic
Immune Epitope Database (IEDB): 2018 update
Abstract. The Immune Epitope Database (IEDB, iedb.org) captures experimental data confined in figures, text and tables of the scientific literature, making it f
See the CoVID-19 effect in India- https://www.science.org/doi/10.1126/science.abm5154
Get an overview of the extrapulmonary complications of COVID-19 from immunological and pathophysiologic perspectives and the pathogenesis and potential therapeutic targets for the management of COVID-19 on https://www.nature.com/articles/s41392-022-00907-1
Nature
The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication
Signal Transduction and Targeted Therapy - The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication
drug_repurposing_Rajput.pdf
4.5 MB
Have you thought of applying Deep learning and machine learning in predicting drugs for CoVID-19. Here is one paper describing the same.
Forwarded from Dollar Education
Dear participants,
We have an update on our schedule for our Monday session. The time for this session is changed to 7PM IST from 6PM IST.
Please note that the time is updated only for this session. The rest of sessions will occur at the same time, 6PM IST.
We apologize for any inconvenience it may have caused.
Thank you,
Team Dollar Education
#LetsGrowTogether
We have an update on our schedule for our Monday session. The time for this session is changed to 7PM IST from 6PM IST.
Please note that the time is updated only for this session. The rest of sessions will occur at the same time, 6PM IST.
We apologize for any inconvenience it may have caused.
Thank you,
Team Dollar Education
#LetsGrowTogether
Forwarded from Dollar Education Discussion
💥 Bulk and Single Cell RNA Sequencing Analysis💥
Interested in learning how to analyse Bulk and Single Cell RNA Seq data? Here, we offer an online workshop on this topic with expert speakers and live demo sessions. Check out www.dollareducation.org
👉🏻ENROLL FAST
🗓 Date: 11- 20 April, 2022
⏰ Time: 6:00 pm IST
✍️ Registration Link
https://www.dollareducation.org
💲 Fees: Rupees 1200 for Indian Participants /USD 25 for international Participants
💥Topics:
▫️Linux and R programming
▫️Reference based and de novo assembly
▫️Quantification of RNA transcripts
▫️Introduction to scRNAseq
▫️Integrating multiple datasets in scRNAseq analysis
▫️Differential gene expression
▫️Gene enrichment analysis
ℹ️Contact and More information:
https://t.me/+qCL0SBRZSLZmMDE1
Interested in learning how to analyse Bulk and Single Cell RNA Seq data? Here, we offer an online workshop on this topic with expert speakers and live demo sessions. Check out www.dollareducation.org
👉🏻ENROLL FAST
🗓 Date: 11- 20 April, 2022
⏰ Time: 6:00 pm IST
✍️ Registration Link
https://www.dollareducation.org
💲 Fees: Rupees 1200 for Indian Participants /USD 25 for international Participants
💥Topics:
▫️Linux and R programming
▫️Reference based and de novo assembly
▫️Quantification of RNA transcripts
▫️Introduction to scRNAseq
▫️Integrating multiple datasets in scRNAseq analysis
▫️Differential gene expression
▫️Gene enrichment analysis
ℹ️Contact and More information:
https://t.me/+qCL0SBRZSLZmMDE1
Since, we are coming with Bulk and Single Cell RNA Sequencing, I would request everyone to go join us there.
We are providing general Reading material for the same.
Get to know the RNA Sequencing and it's Analysis on https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863231/
We are providing general Reading material for the same.
Get to know the RNA Sequencing and it's Analysis on https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863231/
PubMed Central (PMC)
RNA Sequencing and Analysis
RNA sequencing (RNA-Seq) uses the capabilities of high-throughput sequencing methods to provide insight into the transcriptome of a cell. Compared to previous Sanger sequencing- and microarray-based methods, RNA-Seq provides far higher coverage and greater…
Want to know what lncRNA can do ?
Check out this book chapter: https://link.springer.com/chapter/10.1007/978-981-16-5993-5_3
Check out this book chapter: https://link.springer.com/chapter/10.1007/978-981-16-5993-5_3
SpringerLink
An Overview of Databases and Tools for lncRNA Genomics Advancing Preci
The completion of the human genome project revealed many elusive questions about the “junk DNA” in the genome. One of the promising observations was the pervasive transcription and discovery of noncoding RNAs, which put aside the assumption of RNA as a...
Rapid progress in the development of next-generation sequencing (NGS) technologies in recent years has provided many valuable insights into complex biological systems, ranging from cancer genomics to diverse microbial communities. NGS-based technologies for genomics, transcriptomics, and epigenomics are now increasingly focused on the characterization of individual cells.
Learn more in the topic on: https://www.nature.com/articles/s12276-018-0071-8
Learn more in the topic on: https://www.nature.com/articles/s12276-018-0071-8
Nature
Single-cell RNA sequencing technologies and bioinformatics pipelines
Experimental & Molecular Medicine - Showing which genes are expressed, or switched on, in individual cells may help to reveal the first signs of disease. Each cell in an organism contains the...
In the few years since its initial application, massively parallel cDNA sequencing, or RNA-seq, has allowed many advances in the characterization and quantification of transcriptomes. Recently, several developments in RNA-seq methods have provided an even more complete characterization of RNA transcripts. These developments include improvements in transcription start site mapping, strand-specific measurements, gene fusion detection, small RNA characterization and detection of alternative splicing events. Ongoing developments promise further advances in the application of RNA-seq, particularly direct RNA sequencing and approaches that allow RNA quantification from very small amounts of cellular materials.
Read Full Review on: https://www.nature.com/articles/nrg2934
Read Full Review on: https://www.nature.com/articles/nrg2934
Nature
RNA sequencing: advances, challenges and opportunities
Nature Reviews Genetics - Recent developments in methods for RNA sequencing have led to an increased understanding of transcriptomes — both qualitative and quantitative. Ongoing developments...
📄Single-cell RNA sequencing technologies and applications: A brief overview
📘 Journal: Clinical and Translational Medicine (I.F.=11.492)
🗓Publish year: 29 March 2022
🖇 https://onlinelibrary.wiley.com/doi/10.1002/ctm2.694
📘 Journal: Clinical and Translational Medicine (I.F.=11.492)
🗓Publish year: 29 March 2022
🖇 https://onlinelibrary.wiley.com/doi/10.1002/ctm2.694
📄Do you that we can able to identify biomarkers involved in the disease by RNA Sequencing. Learn how RNA Sequencing is used for COVID-19 patients and identifies neutrophil activation biomarkers as a promising diagnostic platform for infections.
📘 Journal: PLoS One (I.F.= 3.24)
🗓Publish year: January 26, 2022
🖇 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0261679
📘 Journal: PLoS One (I.F.= 3.24)
🗓Publish year: January 26, 2022
🖇 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0261679
journals.plos.org
RNA Sequencing in COVID-19 patients identifies neutrophil activation biomarkers as a promising diagnostic platform for infections
Infection with the SARS-CoV2 virus can vary from asymptomatic, or flu-like with moderate disease, up to critically severe. Severe disease, termed COVID-19, involves acute respiratory deterioration that is frequently fatal. To understand the highly variable…