الصورة من مسلسل Mouse 🖤
المسلسل الذي جعلني أحب الدراما الكورية، بعد أن كنت من أشد المعارضين لها.
القصه خرافيه😁

🛑Erectile dysfunction (ED)

✅🧠 Young + Healthy → Think Psychological causes first.
✅🫀 New-onset ED → Consider cardiovascular risk assessment.

🛑Why assess cardiovascular risk?

✅The penile arteries are relatively small, so vascular dysfunction may become clinically apparent in the penile circulation before symptomatic coronary artery disease develops.

🔥 انتظروا معلومات قيّمة اليوم 😉😍😂
من قلب الـ MRCP Notes & Notes 📚💪
جرعة علمية دسمة… ومعلومات تستحق الحفظ 👌🧠
جاهزين للتحدي؟ 😎🔥

🛑Primary Biliary Cholangitis (PBC

👩 Middle-aged woman
😣 Pruritus
🧪 ↑ ALP
🧬 AMA-M2 positive
🩸 ↑ IgM
👉 Primary Biliary Cholangitis (PBC)

🛑⭐ MRCP Pearl

✅↑ ALP + ↑ GGT → Hepatobiliary (liver/biliary) source

✅↑ ALP + Normal GGT → Think of a bone source

🛑 LFTs — MRCP High-Yield Pearls

✅ GGT → Drugs + Alcohol + Fatty liver

✅ ALP → Liver OR Bone

✅ ↑ ALP + ↑ GGT → Hepatobiliary source

✅ ↑ ALP + Normal GGT → Bone source
→ Paget’s disease
→ Osteomalacia
→ Bone metastases
→ Healing fractures

🅰 Very high AST/ALT → Think of:
→ Ischaemic hepatitis
→ Paracetamol overdose

🅱 AST/ALT level ≠ Liver function
→ Transaminases reflect hepatocellular injury, not necessarily the degree of hepatic dysfunction.

🆑 Synthetic liver function → INR + Albumin
→ INR is particularly useful for assessing hepatic synthetic function.

🛑 Clinical Pearl:

✅ALP ↑ + Ca ↑ → Think Hyperparathyroidism / Bone metastases

✅ALP ↑ + Ca ↓ → Think Osteomalacia / Renal failure