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1. A method of vaccinating a person against COVID-19 and all variants thereof, the method comprising:
incubating a dendritic cell culture of a receptor binding domain of a Sigma One portion of a Spike Protein of a COVID-19 virus, or any variant of a COVID-19 virus;
separating a plurality of microRNA exosomes from the dendritic cell culture; and
administering the plurality of microRNA exosomes to the person, the plurality of microRNA exosomes conferring to the person T-cell and B-cell immunity against COVID-19 and all variants of COVID-19.

2. The method of claim 1, wherein the plurality of microRNA exosomes is encapsulated.

3. The method of claim 1, wherein administering the plurality of microRNA exosomes to the person includes encapsulating the plurality of microRNA exosomes in a delayed release capsule so as to target intestinal antigen-presenting cells in the terminal ileum.

4. A composition for vaccinating against a molecule-caused disease, the composition comprising: one or more dendritic-derived exosomes isolated from one or more dendritic cells incubated with an immunogenic substance associated with the molecule-caused disease.



ABSTRACT

A non-antigenic microRNA exosomal vaccination that includes dendritic-derived exosomes resulting from the incubation of dendritic cells with Spike Protein of a COVID-19 virus so that the dendritic cells process the Spike Protein of the COVID-19 virus to enable education of naïve T-cells. The exosomes so-derived are then harvested and encapsulated for delayed release oral capsule delivery to selectively reach intestinal antigen-presenting cells in the terminal ileum for stimulating an acquired immune response to the Spike Protein of the COVID-19 virus. The intestinal antigen-presenting cells incorporate the dendritic-derived exosomes, and thereby learn to recognize the Spike Protein as a threat, even though no dangerous antigens, RNA, or DNA modifications of the antigen or Spike Protein of the COVID-19 virus were introduced by the non-antigenic microRNA exosomal vaccine, thereby avoiding creation of new pandemic viral emergencies, cytokine storms, mitochondrial aerobic failure, serious illnesses, and death via mutated strains of the COVID-19 virus.