π A Little Book of R For Bioinformatics
By: Dr Avril Coghlan - from Sanger Institute
π₯This is a simple introduction to bioinformatics, with a focus on genome analysis, using the R statistics software. To encourage research into neglected tropical diseases such as leprosy, Chagas disease, trachoma, schistosomiasis etc., most of the examples in this booklet are for analysis of the genomes of the organisms that cause these diseases.
π Read the book
π²Channel: @Bioinformatics
By: Dr Avril Coghlan - from Sanger Institute
π₯This is a simple introduction to bioinformatics, with a focus on genome analysis, using the R statistics software. To encourage research into neglected tropical diseases such as leprosy, Chagas disease, trachoma, schistosomiasis etc., most of the examples in this booklet are for analysis of the genomes of the organisms that cause these diseases.
π Read the book
π²Channel: @Bioinformatics
π1
πMachine learning in medicine: a practical introduction to natural language processing
π₯The methods of this paper is structured into four parts, which in turn cover:
1. Basic NLP techniques for data cleaning in open-text datasets
2. Positive and negative sentiment analysis of drug reviews, with a freely-available lexicon
3. Unsupervised machine learning to identify similarities and differences between drugs, based on the words used to describe them
4. Supervised machine learning (classification) to predict whether a free text drug review will be associated with a dichotomised βGoodβ or βBadβ numerical score
We present samples of code written using the R Statistical Programming Language within the paper to illustrate the methods described, and provide the full script as a supplementary file. At points in the analysis, we deliberately simplify and shorten the dataset so that these analyses can be reproduced in reasonable time on a personal desktop or laptop, although this would clearly be suboptimal for original research studies.
While this paper is intended for readers who are relatively new to the field, some basic familiarity with the R programming language and machine learning concepts will make this manuscript easier to follow.
πStudy the paper
π²Channel: @Bioinformatics
π₯The methods of this paper is structured into four parts, which in turn cover:
1. Basic NLP techniques for data cleaning in open-text datasets
2. Positive and negative sentiment analysis of drug reviews, with a freely-available lexicon
3. Unsupervised machine learning to identify similarities and differences between drugs, based on the words used to describe them
4. Supervised machine learning (classification) to predict whether a free text drug review will be associated with a dichotomised βGoodβ or βBadβ numerical score
We present samples of code written using the R Statistical Programming Language within the paper to illustrate the methods described, and provide the full script as a supplementary file. At points in the analysis, we deliberately simplify and shorten the dataset so that these analyses can be reproduced in reasonable time on a personal desktop or laptop, although this would clearly be suboptimal for original research studies.
While this paper is intended for readers who are relatively new to the field, some basic familiarity with the R programming language and machine learning concepts will make this manuscript easier to follow.
πStudy the paper
π²Channel: @Bioinformatics
BioMed Central
Machine learning in medicine: a practical introduction to natural language processing - BMC Medical Research Methodology
Background Unstructured text, including medical records, patient feedback, and social media comments, can be a rich source of data for clinical research. Natural language processing (NLP) describes a set of techniques used to convert passages of written textβ¦
πAll about NCBI
β«οΈWhat is NCBI?
β«οΈNCBI Resources and Tools?
β«οΈNCBI's How To Tasks
β«οΈQuick Guide to Entrez Databases
π See the page
π²Channel: @Bioinformatics
β«οΈWhat is NCBI?
β«οΈNCBI Resources and Tools?
β«οΈNCBI's How To Tasks
β«οΈQuick Guide to Entrez Databases
π See the page
π²Channel: @Bioinformatics
πApplication of social network analysis to COVID-19 data
π Read the paper
π²Channel: @Bioinformatics
π Read the paper
π²Channel: @Bioinformatics
π Lessons from the Pandemic for Machine Learning and Medical Imaging
π₯Presented on behalf of Isaac Newton Institute for Mathematical Sciences
π Watch
π²Channel: @Bioinformatics
π₯Presented on behalf of Isaac Newton Institute for Mathematical Sciences
π Watch
π²Channel: @Bioinformatics
ππ¬Online tutorial
β‘οΈIntroductory bioinformatics
A curated set of EMBL-EBI online courses
This curated pathway brings together a number of online tutorials and recorded webinars to provide an introduction to bioinformatics, a brief tour of the resources available from EMBL-EBI and more details about some of those resources, including Ensembl, UniProt and Expression Atlas.
β¦οΈWhat will you achieve?
By the end of the course you will be able to:
β«οΈOutline what bioinformatics is
β«οΈDescribe the importance of data management
β«οΈRecall which resources are available from EMBL-EBI
β«οΈKnow where to find information about genes
β«οΈView information on gene expression
β«οΈSearch for protein information
β«οΈKnow where to find out more about EMBL-EBI resources
π Enter Course
π²Channel: @Bioinformatics
β‘οΈIntroductory bioinformatics
A curated set of EMBL-EBI online courses
This curated pathway brings together a number of online tutorials and recorded webinars to provide an introduction to bioinformatics, a brief tour of the resources available from EMBL-EBI and more details about some of those resources, including Ensembl, UniProt and Expression Atlas.
β¦οΈWhat will you achieve?
By the end of the course you will be able to:
β«οΈOutline what bioinformatics is
β«οΈDescribe the importance of data management
β«οΈRecall which resources are available from EMBL-EBI
β«οΈKnow where to find information about genes
β«οΈView information on gene expression
β«οΈSearch for protein information
β«οΈKnow where to find out more about EMBL-EBI resources
π Enter Course
π²Channel: @Bioinformatics
π½ Analysis of Viral Sequencing Data
π₯Recorded lecture from Computational Genomics Summer Institute: CGSI
π Watch
π²Channel: @Bioinformatics
π₯Recorded lecture from Computational Genomics Summer Institute: CGSI
π Watch
π²Channel: @Bioinformatics
YouTube
Alex Zelikovsky | Analysis of Viral Sequencing Data | CGSI 2019
Speaker: Alex Zelikovsky
Talk: " Analysis of Viral Sequencing Data"
Location: Mong Auditorium, 7/18/19
Talk: " Analysis of Viral Sequencing Data"
Location: Mong Auditorium, 7/18/19
π¨βπ« Introduction to R for Health Data Science
π₯Free online course from University of Manchester
π Enter the course
π²Channel: @Bioinformatics
π₯Free online course from University of Manchester
π Enter the course
π²Channel: @Bioinformatics
πReproducible Bioinformatics Research for Biologists
π½ Download book chapter
π²Channel: @Bioinformatics
π½ Download book chapter
π²Channel: @Bioinformatics
πMachine learning in medicine: a practical introduction
π₯We address the need for capacity development in this area by providing a conceptual introduction to machine learning alongside a practical guide to developing and evaluating predictive algorithms using freely-available open source software and public domain data.
π Read the paper
π²Channel: @Bioinformatics
π₯We address the need for capacity development in this area by providing a conceptual introduction to machine learning alongside a practical guide to developing and evaluating predictive algorithms using freely-available open source software and public domain data.
π Read the paper
π²Channel: @Bioinformatics
π¬Free webinar
π§βπ»Designing and Optimizing RNA-Seq Experiments
Learning Objectives:
β«οΈKnow Available RNA sequencing technologies and their applications
β«οΈOptimizing library preparation depending on the sequencing platform
β«οΈHow to obtain the proper sample quality required for each RNA sequencing technology
β«οΈThe importance of replicate numbers to obtain reliable results
π Date:
Monday, September 27, 2021
π Time:
11:00 AM - 12:00 PM Eastern Time
βοΈ Registration and more details
π²Channel: @Bioinformatics
π§βπ»Designing and Optimizing RNA-Seq Experiments
Learning Objectives:
β«οΈKnow Available RNA sequencing technologies and their applications
β«οΈOptimizing library preparation depending on the sequencing platform
β«οΈHow to obtain the proper sample quality required for each RNA sequencing technology
β«οΈThe importance of replicate numbers to obtain reliable results
π Date:
Monday, September 27, 2021
π Time:
11:00 AM - 12:00 PM Eastern Time
βοΈ Registration and more details
π²Channel: @Bioinformatics
ππΊGenomics Boot Camp (Online Book + YouTube channel)
π₯The Genomics Boot Camp is a resource that helps you to start your journey in practical analysis of genomic data, with a focus on SNP data. The chapters follow the same structure all the time: provide background information and practical insight to the topic, and when appropriate exercises to reinforce the obtained knowledge. The Genomics Boot Camp as a whole was designed to cater to various learning preferences with written text, video demonstrations, and the possibility of hands-on exercises. There is a certain overlap between the book and the YouTube channel contents, but each has unique pieces of information as well. So for the full experience, I suggest checking out both.
π¦ Movies
πOnline Tutorial
π²Channel: @Bioinformatics
π₯The Genomics Boot Camp is a resource that helps you to start your journey in practical analysis of genomic data, with a focus on SNP data. The chapters follow the same structure all the time: provide background information and practical insight to the topic, and when appropriate exercises to reinforce the obtained knowledge. The Genomics Boot Camp as a whole was designed to cater to various learning preferences with written text, video demonstrations, and the possibility of hands-on exercises. There is a certain overlap between the book and the YouTube channel contents, but each has unique pieces of information as well. So for the full experience, I suggest checking out both.
π¦ Movies
πOnline Tutorial
π²Channel: @Bioinformatics
π₯1
πBioinformatics core competencies for undergraduate life sciences education
From Paper Abstract: Although bioinformatics is becoming increasingly central to research in the life sciences, bioinformatics skills and knowledge are not well integrated into undergraduate biology education. This curricular gap prevents biology students from harnessing the full potential of their education, limiting their career opportunities and slowing research innovation. To advance the integration of bioinformatics into life sciences education, a framework of core bioinformatics competencies is needed. To that end, we here report the results of a survey of biology faculty in the United States about teaching bioinformatics to undergraduate life scientists. Responses were received from 1,260 faculty representing institutions in all fifty states with a combined capacity to educate hundreds of thousands of students every year...
π Read the paper
π²Channel: @Bioinformatics
From Paper Abstract: Although bioinformatics is becoming increasingly central to research in the life sciences, bioinformatics skills and knowledge are not well integrated into undergraduate biology education. This curricular gap prevents biology students from harnessing the full potential of their education, limiting their career opportunities and slowing research innovation. To advance the integration of bioinformatics into life sciences education, a framework of core bioinformatics competencies is needed. To that end, we here report the results of a survey of biology faculty in the United States about teaching bioinformatics to undergraduate life scientists. Responses were received from 1,260 faculty representing institutions in all fifty states with a combined capacity to educate hundreds of thousands of students every year...
π Read the paper
π²Channel: @Bioinformatics
2021_Differential_Expression_Analysis_of_RNA_Seq_Data_and_Co_expression.pdf
9.8 MB
πPractical Differential Expression Analysis of RNA-Seq Data and Co-expression Networks
π²Channel: @Bioinformatics
π²Channel: @Bioinformatics
π π Pathways and Network Analysis 2021
π¨π»βπ»3 days full workshop details
π Workshop details
π²Channel: @Bioinformatics
π¨π»βπ»3 days full workshop details
π Workshop details
π²Channel: @Bioinformatics
π·Job opportunity
π¨βπ«Eligibility: Master or PhD degree in Bioinformatics, Computational Biology or similar area.
πContract type: Pemanent contract
π¦Work Hours: Full time - 40h/week
πLocation: Strassen (Luxembourg)
π Start date: immediate
βΉοΈ More info and apply
π²Channel: @Bioinformatics
π¨βπ«Eligibility: Master or PhD degree in Bioinformatics, Computational Biology or similar area.
πContract type: Pemanent contract
π¦Work Hours: Full time - 40h/week
πLocation: Strassen (Luxembourg)
π Start date: immediate
βΉοΈ More info and apply
π²Channel: @Bioinformatics
π΅ 25 awarded funds across 30 U.S. research sites
π₯NIH providing $185 million for research to advance understanding of how human genome functions
βΉοΈ More information
π²Channel: @Bioinformatics
π₯NIH providing $185 million for research to advance understanding of how human genome functions
βΉοΈ More information
π²Channel: @Bioinformatics
πΉIntroduction to Weighted Gene Co-expression Network Analysis (WGCNA)
π₯recorded webinar
π Goals:
β«οΈIntroduction and motivation for co-expression network analysis
β«οΈBasics of weighted gene co-expression network analysis
β«οΈStep-by-step guide to WGCNA using the WGCNA package in R.
π Watch
π²Channel: @Bioinformatics
π₯recorded webinar
π Goals:
β«οΈIntroduction and motivation for co-expression network analysis
β«οΈBasics of weighted gene co-expression network analysis
β«οΈStep-by-step guide to WGCNA using the WGCNA package in R.
π Watch
π²Channel: @Bioinformatics
YouTube
Webinar #7 β Introduction to Weighted Gene Co-expression Network Analysis
Goals of this webinar (molecular networks):
Introduction and motivation for co-expression network analysis
Basics of weighted gene co-expression network analysis
Step-by-step guide to WGCNA using the wgcna package in R.
Background reading available at: hβ¦
Introduction and motivation for co-expression network analysis
Basics of weighted gene co-expression network analysis
Step-by-step guide to WGCNA using the wgcna package in R.
Background reading available at: hβ¦