π Harnessing Artificial Intelligence for Genomic Variant Prediction: Advances, Challenges, and Future Directions
π Journal: GigaScience
πPublish year: 2026
π§βπ»Authors: Indah Pakpahan, Mentari Sihombing, Haohan Liu,...
π’Universities: Dalian University of Technology, China - The University of New South Wales, Australia
π Study the paper
π²Channel: @Bioinformatics
#review #variant #genomic #ai
π Journal: GigaScience
πPublish year: 2026
π§βπ»Authors: Indah Pakpahan, Mentari Sihombing, Haohan Liu,...
π’Universities: Dalian University of Technology, China - The University of New South Wales, Australia
π Study the paper
π²Channel: @Bioinformatics
#review #variant #genomic #ai
β€3π3
πFoundation Models in Omics Research: A Comprehensive Survey
πPublish year: 2026
π§βπ»Authors: Haozhe Liu, Wenhao Cai, Yizheng Sun
π’University: The University of Manchester, United Kingdom
π Study the paper
π²Channel: @Bioinformatics
#review #llm #foundation_model #omics #ai
πPublish year: 2026
π§βπ»Authors: Haozhe Liu, Wenhao Cai, Yizheng Sun
π’University: The University of Manchester, United Kingdom
π Study the paper
π²Channel: @Bioinformatics
#review #llm #foundation_model #omics #ai
β€5
π Learnable protein representations in computational biology for predicting drug-target affinity
π Journal: Journal of Cheminformatics (I.F.=5.7)
πPublish year: 2026
π§βπ»Authors: Rachit Kumar, Joseph Romano & Marylyn Ritchie
π’Universities: University of Pennsylvania & Medical University of South Carolina, USA
π Study the paper
π²Channel: @Bioinformatics
#review #drug #target #protein #representation
π Journal: Journal of Cheminformatics (I.F.=5.7)
πPublish year: 2026
π§βπ»Authors: Rachit Kumar, Joseph Romano & Marylyn Ritchie
π’Universities: University of Pennsylvania & Medical University of South Carolina, USA
π Study the paper
π²Channel: @Bioinformatics
#review #drug #target #protein #representation
π1π1
πNavigating the Computational Landscape for Drug Repurposing
π Journal: Annual Review of Pharmacology and Toxicology (I.F.=13.1)
πPublish year: 2026
π§βπ»Authors: Andrea Γlvarez-PΓ©rez, LucΓa Prieto-SantamarΓa, Ana I. Casas,...
π’University: Universidad PolitΓ©cnica de Madrid, Spain - Maastricht University, The Netherlands - University Clinic Essen, Germany - Harvard Medical School, USA
π Study the paper
π²Channel: @Bioinformatics
#review #drug #repurposing
π Journal: Annual Review of Pharmacology and Toxicology (I.F.=13.1)
πPublish year: 2026
π§βπ»Authors: Andrea Γlvarez-PΓ©rez, LucΓa Prieto-SantamarΓa, Ana I. Casas,...
π’University: Universidad PolitΓ©cnica de Madrid, Spain - Maastricht University, The Netherlands - University Clinic Essen, Germany - Harvard Medical School, USA
π Study the paper
π²Channel: @Bioinformatics
#review #drug #repurposing
π5β€1
πΉ Leveraging Genomic, Preclinical, and Drug Response Data in the Age of AI
π₯Dr. Michael Boice from Certis Oncology
π Watch
π²Channel: @Bioinformatics
#video #genomic #drug #ai
π₯Dr. Michael Boice from Certis Oncology
π Watch
π²Channel: @Bioinformatics
#video #genomic #drug #ai
YouTube
Leveraging Genomic, Preclinical, and Drug Response Data in the Age of AI
Join Dr. Michael Boice from Certis Oncology for a discussion and demonstration of how artificial intelligence can improve preclinical decision-making in cancer research.
Molecular profiling and other tumor model characterization data are becoming increasinglyβ¦
Molecular profiling and other tumor model characterization data are becoming increasinglyβ¦
π4β€1
π AI-Powered Single-Cell RNA-seq β 7-Minute Runtime Report
How can AI streamline end-to-end single-cell RNA analysis?
In this session, we demonstrate how Drylab enables:
π¬ End-to-end single-cell RNA workflow
β’ Data preprocessing
β’ Advanced analysis
β’ Automated reporting
π¬ Natural-language chat to explore and interpret results
π» Full code environment for transparency
π Clear, reproducible outputs ready for review and sharing
π Read the full case study:
https://thedrylab.com/use-case/comprehensive-multi-organ-endothelial-cell-atlas-analysis-and-liver-specific
π§ͺ Explore the full chat + code environment:
https://app.thedrylab.com/share/wLRjnJxzWVYz
π²Channel: @Bioinformatics
How can AI streamline end-to-end single-cell RNA analysis?
In this session, we demonstrate how Drylab enables:
π¬ End-to-end single-cell RNA workflow
β’ Data preprocessing
β’ Advanced analysis
β’ Automated reporting
π¬ Natural-language chat to explore and interpret results
π» Full code environment for transparency
π Clear, reproducible outputs ready for review and sharing
π Read the full case study:
https://thedrylab.com/use-case/comprehensive-multi-organ-endothelial-cell-atlas-analysis-and-liver-specific
π§ͺ Explore the full chat + code environment:
https://app.thedrylab.com/share/wLRjnJxzWVYz
π²Channel: @Bioinformatics
Thedrylab
Drylab Use Cases: Single-Cell RNA-sequencing to profile Endothelial cells across organs
Explore how biotech teams use Drylab for biomarker discovery, patient stratification, drug target ID, and single-cell analysis.
π6β€3
π Federated learning frameworks: quality and interoperability for biomedical research
π Journal: NAR Genomics and Bioinformatics (I.F.=2.8)
πPublish year: 2026
π§βπ»Authors: MarΓa Chavero-Diez, Carles Hernandez-Ferrer, Laia CodΓ³, ...
π’Universities: Barcelona Supercomputing Center (BSC) & University of Barcelona, Spain
π Study the paper
π²Channel: @Bioinformatics
#review #federated_learning
π Journal: NAR Genomics and Bioinformatics (I.F.=2.8)
πPublish year: 2026
π§βπ»Authors: MarΓa Chavero-Diez, Carles Hernandez-Ferrer, Laia CodΓ³, ...
π’Universities: Barcelona Supercomputing Center (BSC) & University of Barcelona, Spain
π Study the paper
π²Channel: @Bioinformatics
#review #federated_learning
π3
π Systematic review of transformers, graph neural networks, and federated learning in oncology: Applications, challenges, and pathways to clinical translation
Journal: Informatics in Medicine Unlocked
πPublish year: 2026
π§βπ»Authors: Sasan Shafiei, Atousa Saleknezhad, Erfan Hashemi , ...
π’Universities: Shiraz University of Medical Sciences & Babol University of Medical Sciences & Tehran University of Medical Sciences & Jahrom University of Medical Sciences, Iran
π Study the paper
π²Channel: @Bioinformatics
#review #transformers #oncology #deep_learning
Journal: Informatics in Medicine Unlocked
πPublish year: 2026
π§βπ»Authors: Sasan Shafiei, Atousa Saleknezhad, Erfan Hashemi , ...
π’Universities: Shiraz University of Medical Sciences & Babol University of Medical Sciences & Tehran University of Medical Sciences & Jahrom University of Medical Sciences, Iran
π Study the paper
π²Channel: @Bioinformatics
#review #transformers #oncology #deep_learning
π2
π Artificial Intelligence to Guide Repurposing of Drugs
π Journal: Annual Review of Medicine (π₯I.F.=22.1)
πPublish year: 2026
π§βπ»Authors: Zhimin Fu, Yuxin Yang, Mina K. Chung, ...
π’Universities: University Hospitals of Cleveland, Cleveland & Case Western Reserve University & Lerner Research Institute, USA
π Study the paper
π²Channel: @Bioinformatics
#review #repurposing #drug
π Journal: Annual Review of Medicine (π₯I.F.=22.1)
πPublish year: 2026
π§βπ»Authors: Zhimin Fu, Yuxin Yang, Mina K. Chung, ...
π’Universities: University Hospitals of Cleveland, Cleveland & Case Western Reserve University & Lerner Research Institute, USA
π Study the paper
π²Channel: @Bioinformatics
#review #repurposing #drug
π3β€1
π Cognition, Cytokines, BloodβBrain Barrier, and Beyond in COVID-19: A Narrative Review
πJournal: International Journal of Molecular Sciences (I.F.=4.9)
πPublish year: 2026
π§βπ»Authors: Ana Barajas, Gemma Riquelme-Alacid, AmΓ©rica Vera-Montecinos, and BelΓ©n Ramos
π’Universities: Universitat AutΓ²noma de Barcelona & Institut de Recerca Sant Joan de DΓ©u, Spain - Universidad San SebastiΓ‘n, Chile
π Study the paper
π²Channel: @Bioinformatics
#review #covid_19 #Cognition #Cytokines
πJournal: International Journal of Molecular Sciences (I.F.=4.9)
πPublish year: 2026
π§βπ»Authors: Ana Barajas, Gemma Riquelme-Alacid, AmΓ©rica Vera-Montecinos, and BelΓ©n Ramos
π’Universities: Universitat AutΓ²noma de Barcelona & Institut de Recerca Sant Joan de DΓ©u, Spain - Universidad San SebastiΓ‘n, Chile
π Study the paper
π²Channel: @Bioinformatics
#review #covid_19 #Cognition #Cytokines
β€3π1
π A Survey on Multimodal AI and Agent Systems for Biology: Perception, Reasoning, Generation, and Automation
πPublish year: 2026
π§βπ»Authors: Emily Johnson, Zihan Dong
π’University: University of Massachusetts Amherst, USA
π Study the paper
π²Channel: @Bioinformatics
#review #ai #multimodal
πPublish year: 2026
π§βπ»Authors: Emily Johnson, Zihan Dong
π’University: University of Massachusetts Amherst, USA
π Study the paper
π²Channel: @Bioinformatics
#review #ai #multimodal
π5
π AI-Based Prediction of Gene Expression in Single-Cell and Multiscale Genomics and Transcriptomics
π Journal:International Journal of Molecular Sciences (I.F.=4.9)
πPublish year: 2026
π§βπ»Authors: Ema Andreea PΔlΔΘtea, Irina-Mihaela Matache,Eugen Radu, ...
π’Universities: Genomics Research and Development Institute & Carol Davila University of Medicine and Pharmacy & Emergency University Hospital, Romania - Yale School of Medicine & Viron Molecular Medicine Institute, USA
π Study the paper
π²Channel: @Bioinformatics
#review #ai #gene_expression #single_cell
π Journal:International Journal of Molecular Sciences (I.F.=4.9)
πPublish year: 2026
π§βπ»Authors: Ema Andreea PΔlΔΘtea, Irina-Mihaela Matache,Eugen Radu, ...
π’Universities: Genomics Research and Development Institute & Carol Davila University of Medicine and Pharmacy & Emergency University Hospital, Romania - Yale School of Medicine & Viron Molecular Medicine Institute, USA
π Study the paper
π²Channel: @Bioinformatics
#review #ai #gene_expression #single_cell
π4β€1
π A Survey on Efficient Protein Language Models
πPublish year: 2025
π§βπ»Authors: Shouren Wang, Debargha Ganguly, Vinooth Kulkarni, ...
π’University: Case Western Reserve University, Cleveland Clinic, USA
π Study the paper
π²Channel: @Bioinformatics
#review #ai #llm #protein
πPublish year: 2025
π§βπ»Authors: Shouren Wang, Debargha Ganguly, Vinooth Kulkarni, ...
π’University: Case Western Reserve University, Cleveland Clinic, USA
π Study the paper
π²Channel: @Bioinformatics
#review #ai #llm #protein
π5β€2
π Gene regulatory networks: from correlative models to causal explanations
π Journal: Nature Reviews Genetics (I.F.=β‘οΈ52)
πPublish year: 2026
π§βπ»Authors: Rory J. Maizels & James Briscoe
π’ University: The Francis Crick Institute, London, UK
π Study the paper
π²Channel: @Bioinformatics
#review #grn #gene #regulatory
π Journal: Nature Reviews Genetics (I.F.=β‘οΈ52)
πPublish year: 2026
π§βπ»Authors: Rory J. Maizels & James Briscoe
π’ University: The Francis Crick Institute, London, UK
π Study the paper
π²Channel: @Bioinformatics
#review #grn #gene #regulatory
Nature
Gene regulatory networks: from correlative models to causal explanations
Nature Reviews Genetics - In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without...
β€3
π Registration is open for the One-Month Comprehensive International Bioinformatics Workshop by Decode Life
π₯ Generative AI for Bioinformatics - with Python π₯
π Duration: 14 March - 9 April 2026
π² Fees: βΉ1300 for Indian Participants / $30 for International Participants
π Registration Link:
https://decodelife.co.in/
β¨ Key Features:
β 21 sessions with approximately 35 hours of learning
β E-Certificate of Participation
β Video recordings and relevant material shared after each session
β FAQs: https://decodelife.co.in/faq/
π²Channel: @Bioinformatics
π₯ Generative AI for Bioinformatics - with Python π₯
π Duration: 14 March - 9 April 2026
π² Fees: βΉ1300 for Indian Participants / $30 for International Participants
π Registration Link:
https://decodelife.co.in/
β¨ Key Features:
β 21 sessions with approximately 35 hours of learning
β E-Certificate of Participation
β Video recordings and relevant material shared after each session
β FAQs: https://decodelife.co.in/faq/
π²Channel: @Bioinformatics
β€7
Forwarded from Network Analysis Resources & Updates
π Network pharmacology in the multi-omics era: uncovering novel therapeutic strategies
π Journal: Discover Chemistry (I.F.=4.6)
π Publish year: 2026
π§βπ»Authors: Kalyani Ramprasad Thombre, Vaishnavi Gabhane, Krishna Radheshyam Gupta, ...
π’University: Kishoritai Bhoyar College of Pharmacy, India
π Study the paper
π― Article summary:
Network pharmacology represents a transformative approach in drug discovery, moving away from the traditional "one-drug, one-target" model to a systems-oriented framework that acknowledges the complexity of diseases through the integration of multi-omics data and computational methodologies. This review synthesizes current advancements in network pharmacology, highlighting its potential to enhance drug repurposing, precision medicine, and multi-target therapeutic strategies while addressing challenges related to data quality, methodological biases, and the need for rigorous experimental validation.
β‘οΈChannel: @ComplexNetworkAnalysis
#review #pharmacology #omics
π Journal: Discover Chemistry (I.F.=4.6)
π Publish year: 2026
π§βπ»Authors: Kalyani Ramprasad Thombre, Vaishnavi Gabhane, Krishna Radheshyam Gupta, ...
π’University: Kishoritai Bhoyar College of Pharmacy, India
π Study the paper
π― Article summary:
Network pharmacology represents a transformative approach in drug discovery, moving away from the traditional "one-drug, one-target" model to a systems-oriented framework that acknowledges the complexity of diseases through the integration of multi-omics data and computational methodologies. This review synthesizes current advancements in network pharmacology, highlighting its potential to enhance drug repurposing, precision medicine, and multi-target therapeutic strategies while addressing challenges related to data quality, methodological biases, and the need for rigorous experimental validation.
β‘οΈChannel: @ComplexNetworkAnalysis
#review #pharmacology #omics
β€7π1
π Leveraging Natural Language Processing to Unravel the Mystery of Life: A Review of NLP Approaches in Genomics, Transcriptomics, and Proteomics
πPublish year: 2026
π§βπ»Authors: Ella Rannon, David Burstein
π’ University: Tel-Aviv University, Israel
π Study the paper
π²Channel: @Bioinformatics
#review #nlp
πPublish year: 2026
π§βπ»Authors: Ella Rannon, David Burstein
π’ University: Tel-Aviv University, Israel
π Study the paper
π²Channel: @Bioinformatics
#review #nlp
π₯5