Katzung clinical pharmacology
Qbank

1st lecture of #renal pharmacology at
1:38:10

من دقيقة الاولة لحد دقيقة 17 كلش خوش شرح Edema وحيل راح يفيدنا بالباثو الباقي كنسلوه😁😁

Na channel blockers like Triametran and Amiloride

#Renal pharmacology mcqs
من اسئلة المصدر مال كليتنا و اسئلة كليتنا وراح اضيف اسئلة همين

A 78-year-old man with a history of heart disease has difficulty breathing and is diagnosed with acute pulmonary edema. Which drug is contraindicated?
A. Furosemide
B. demeclocycline
C. Mannitol
D. Eplerenone

A 70-year-old retired businessman with a history of chronic heart failure has been taking digoxin and furosemide. He is now admitted with a history of vomiting, acute decom- pensated heart failure, and metabolic derangements. He has marked peripheral edema and metabolic alkalosis (pH, 7.50; pCO2, 45; HCO3, 36; Na+, 140). Which of the following drugs is most appropriate for the treatment of his edema? (A) Acetazolamide
(B) Digoxin
(C) Eplerenone
(D) Hydrochlorothiazide (E) Tolvaptan

A 50-year-old man has a history of frequent episodes of renal colic with calcium-containing renal stones. A careful workup indicates that he has a defect in proximal tubular calcium reabsorption, which results in high concentrations of calcium salts in the tubular urine. The most useful diuretic agent in the treatment of recurrent calcium stones is
(A) Chlorthalidone (B) Diazoxide
(C) Ethacrynic acid (D) Mannitol
(E) Spironolactone

Which of the following is an important effect of chronic therapy with loop diuretics?
(A) Decreased urinary excretion of calcium (B) Elevation of blood pressure
(C) Elevation of pulmonary vascular pressure (D) Metabolic alkalosis
(E) Teratogenic action in pregnancy

Which of the following diuretics would be most useful in the acute treatment of a comatose patient with traumatic brain injury and cerebral edema?
(A) Acetazolamide
(B) Amiloride
(C) Chlorthalidone (D) Furosemide (E) Mannitol

A 62-year-old man with advanced prostate cancer is admit- ted to the emergency department with mental obtundation. An electrolyte panel shows a serum calcium of 16.5 (normal 8.5–10.5 mg/dL). Which of the following therapies would be most useful in the management of severe hypercalcemia?
(A) Acetazolamide plus saline infusion
(B) Furosemide plus saline infusion
(C) Hydrochlorothiazide plus saline infusion (D) Mannitol plus saline infusion
(E) Spironolactone plus saline infusion

A 60-year-old patient complains of paresthesias and occa- sional nausea associated with one of the drugs she is taking. She is found to have hyperchloremic metabolic acidosis. She is probably taking
(A) Acetazolamide for glaucoma
(B) Amiloride for edema associated with aldosteronism (C) Furosemide for severe hypertension and heart failure (D) Hydrochlorothiazide for hypertension
(E) Mannitol for cerebral edema

A 70-year-old woman is admitted to the emergency depart- ment because of a “fainting spell” at home. She appears to have suffered no trauma from her fall, but her blood pres- sure is 120/60 when lying down and 60/20 when she sits up. Neurologic examination and an ECG are within normal limits when she is lying down. Questioning reveals that she has recently started taking “water pills” (diuretics) for a heart condition. Which of the following drugs is the most likely cause of her fainting spell?
(A) Acetazolamide
(B) Amiloride
(C) Furosemide
(D) Hydrochlorothiazide (E) Spironolactone

A 58-year-old woman with lung cancer has abnormally low serum osmolality and hyponatremia. A drug that increases the formation of dilute urine and is used to treat SIADH is (A) Acetazolamide
(B) Amiloride
(C) Desmopressin
(D) Ethacrynic acid
(E) Furosemide
(F) Hydrochlorothiazide (G) Mannitol
(H) Spironolactone
(I) Triamterene
(J) Tolvaptan

A graduate student is planning to make a high-altitude climb in South America while on vacation. He will not have time to acclimate slowly to altitude. A drug that is useful in prevent- ing high-altitude sickness is
(A) Acetazolamide (B) Amiloride
(C) Demeclocycline (D) Desmopressin (E) Ethacrynic acid

The answer is E in both
الاول يعاني من Severe hypokalemia و HTN وماعنده edema ف نكدر ننطيه spiro لان اضرب عصفورين بحجارة وحدة هم اقلل من ضغطه وهم ازيد من K serum
الثاني عدها little knee edema و k serum is normal ف افضل شي تنطيه كذلك من عائلة K STAy مثل Triam.
صح راح يصير شوية Hyperkalemia لكن تكدر تسيطر عليه